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74 articles for “Cardiovascular diseases”
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Research ArticleOpen accessIn the abstractRandom Forest-Based Genome Analysis for Disease Association and SNP Marker IdentificationXiangdong LiuAt present, genomic data analysis has the problems of insufficient model interpretation and limited computational efficiency in disease association research. As a powerful machine learning algorithm, Random Forest has demonstrated excellent ability in processing complex and multi-dimensional data sets and has gradually become a popular tool in the field of bioinformatics. The purpose of this paper is to explore how … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Jul 2025 · 5,536 accessesView PDFCite
Literature ReviewOpen accessIn the abstractUnraveling Sterile Inflammation in Atherosclerosis: Mechanisms, Implications and Therapeutic StrategiesAnastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Anton Yuvenalievich Postnov et al.Atherosclerosis, a leading factor in the development of cardiovascular diseases, is a complex and multifaceted condition with inflammation emerging as a pivotal determinant of its pathogenesis. This review comprehensively investigates the role of sterile inflammation in atherosclerosis and deliberates on potential therapeutic interventions targeting this underlying mechanism. Despite advancements in the understanding of atherosclerosis, diagnosing, preventing, and choosing effective treatment … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 4 Mar 2025 · 3,973 accessesView PDFCite
Literature ReviewOpen accessIn the abstractThe Benefits of Selected Nutritional Compounds Towards Atherosclerosis ManagementAnastasia Vladimirovna Poznyak, Mariam Bagheri Ekta, Vasily Nikolaevich Sukhorukov et al.Globally, the prevalence of obesity, type 2 diabetes, and metabolic syndrome is steadily rising, potentially giving rise to the most extensive non-communicable health crisis ever recorded blocking the flow are able to break and cause a blood clot. The possible consequence is a significant increase in atherosclerotic cardiovascular disease rate. The atherosclerotic cardiovascular disease largely depends on modifiable factors, however, … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 2 Nov 2023 · 5,036 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Association of Blood Serum Atherogenicity with Risk Factors for Cardiovascular DiseaseTatiana Vladimirovna Kirichenko, Igor Alexandrovich Sobenin et al.Cardiovascular Diseases (CVD) caused by atherosclerosis are the most frequent cause of mortality worldwide, so the identification of new biomarkers of atherosclerosis development is quite actual. The atherogenicity of blood serum is considered as the potential of human serum to cause cholesterol accumulation in primary culture macrophages. The current study aimed to evaluate the association of the atherogenicity of blood … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 30 Oct 2023 · 4,921 accessesView PDFCite
Review ArticleOpen accessIn the abstractBrief Overview of Specific Features of Cancer in Atherosclerosis Patients and Therapeutic StrategiesAnastasia Vladimirovna Poznyak, Varvara Alexandrovna Orekhova, Vasily Nikolaevich Sukhorukov et al.Cardiovascular Conditions (CVD) as well as cancer are the main death causes globally. Characteristically, there are numerous interrelations and intersections between these two groups of diseases. So, in particular, cardiovascular disease is one of the main comorbidities and death causes in cancer patients. The development of atherosclerosis is promoted by aggressive anticancer therapy regimens and various risk factors, including hypertension, … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 22 Sep 2023 · 4,526 accessesView PDFCite
Research ArticleOpen accessIn the abstractEarly Responses of Neural Cells (U87) to Particulate Matter Exposure: Cell Viability and Cytokine ConcentrationJae-Sik Jeon, Eun Ju Oh, Qian-Wen Wang, Jae Kyung KimParticulate Matter (PM) has a significant impact on human health and increases the risk of respiratory diseases. PM exposure is linked to various illnesses, including cardiovascular diseases, cancer, neurological diseases, and pregnancy complications, and contributes to both mortality and morbidity globally. PM can also influence the autonomic nervous system. The evidence suggests that the likelihood of developing lung cancer continually … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 20 Feb 2023 · 5,451 accessesView PDFCite
Literature ReviewOpen accessIn the abstractAtherosclerosis and Alzheimer’s Disease Interconnection: Inflammation, Aβ and MoreAnastasia Vladimirovna Poznyak, Victoria Khotina, Roghayyeh Vakili-Ghartavol et al.Despite being the leading cause of CVD and cardiovascular mortality globally, Atherosclerosis (ATH) remains underdiagnosed and undertreated. The reasons behind Alzheimer’s Disease (AD) also remain unclear and there is currently no cure for it. At present, at least 55 million people are believed to be suffering from the disorder and the figures are expected to grow. At the same time, … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 26 May 2024 · 4,764 accessesView PDFCite
Review ArticleOpen accessIn the abstractLong Way of Evaluating Niacin for Atherosclerosis TreatmentAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Elizaveta Mikhailovna Pleshko et al.Atherosclerosis is a significant public health challenge, as it is closely associated with a wide range of cardiovascular diseases and complications. Despite its grave implications, the timely detection and treatment of atherosclerosis remain complex tasks due to the intricate pathogenesis involved, which encompasses numerous processes and mechanisms. Extensive research has been conducted to investigate various therapeutic methods and drugs aimed … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 24 Feb 2024 · 5,123 accessesView PDFCite
Review ArticleOpen accessIn the abstractFemale Sex Hormones Contribute to Vulnerability to Athero-Sclerosis: Overview of Mechanisms and Specific Risk FactorsAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Alexandra Alexandrovna Melnichenko et al.Atherosclerosis poses a significant challenge to the general population, with its prevalence particularly prominent among older individuals. Age, however, is not the sole determinant of risk, as gender also plays a crucial role. Sex-related disparities exist not only in the incidence of atherosclerosis but also in its progression and development. The intricate interplay of hormones in the female reproductive system … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 11 Jan 2024 · 4,635 accessesView PDFCite
Research ArticleOpen accessIn the abstractCardiovascular Disease Prediction through Ensembled Transfer Learning on Cardiac Magnetic Resonance ImagingSibu Cyriac, Sivakumar R., Nidhin RajuCardiovascular Diseases (CVD) cause more deaths worldwide than most of the other diseases. The diagnosis of cardiovascular disease from Magnetic Resonance Imaging plays a major role in the medical field. The technological revolution contributed a lot to increase the effectiveness of CVD diagnosis. Many Artificial Intelligence methods using Deep Learning models are available to assist the cardiologist in the diagnosis … …Journal of Computer Science, Vol. 18, Issue 11 · 2 Nov 2022 · 6,171 accessesView PDFCite