Research ArticleOpen accessIn the abstractRandom Forest-Based Genome Analysis for Disease Association and SNP Marker IdentificationXiangdong LiuAt present, genomic data analysis has the problems of insufficient model interpretation and limited computational efficiency in disease association research. As a powerful machine learning algorithm, Random Forest has demonstrated excellent ability in processing complex and multi-dimensional data sets and has gradually become a popular tool in the field of bioinformatics. The purpose of this paper is to explore how … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Jul 2025 · 5,533 accessesView PDFCite
Research ArticleOpen accessIn the abstractAdvancing Digital Forgery Detection: A Comparative Analysis of U-Net, Buster Net, Efficient B0+ U-Net, and VGG 16+ U-Net ModelsPreeti Dhiman, Usha ChauhanForgery Detection in the area of digital images is indispensable for insuring authenticity, particularly in detecting Copy-Move, Splicing. In this research, a meticulous analysis of latest learning architectures i.e. U-Net, Buster Net, Efficient B0+U-Net and VGG16+U-Net are compared for the detecting these types of forgeries. U-Net is popular due to its potent segmentation capabilities to provide pixel-level forgery localization while … …Journal of Computer Science, Vol. 22, Issue 10 · 8 Oct 2026 · 383 accessesView PDFCite
Research ArticleOpen accessIn the abstractDual-Branch Shape Texture Learning With Pyramid Residual and Sobel Edge Layers for Rice Variety ClassificationM Pradeep, M SiddappaAutomated rice variety classification categorizes rice types based on features, such as grain texture, shape, color, and size. Traditional handcrafted feature-based models fail at rice classification due to lighting variations, background noise, and environmental conditions, leading to overlapping visual characteristics and frequent misclassification. To address these challenges, this research proposes a novel Dual-Branch Convolutional Neural Network with Pyramid Residual Units … …Journal of Computer Science, Vol. 22, Issue 9 · 24 Sep 2026 · 627 accessesView PDFCite
Research ArticleOpen accessIn the abstractUMPM-Net: A Multimodal Deep Learning Framework for Colorectal Cancer PrognosisK. Muthuchamy, S K. Piramu PreethikaColorectal cancer (CRC) is one of the most common cancers worldwide, for which early prediction of patient outcomes is important for personalised treatment planning and to improve survival. However, current prediction systems are limited in the fact that they are based on single-modality data and cannot capture the complex interactions between clinical, imaging, and genomic factors. To overcome these shortcomings, … …Journal of Computer Science, Vol. 22, Issue 9 · 20 Sep 2026 · 613 accessesView PDFCite
Research ArticleOpen accessIn the abstractExplainable MedAttn-ResNet50 for Automated Kidney Tumor Classification from CT Images With Grad-CAM VisualizationD. Vetrithangam, Pramod Kumar, Shilpasree S. et al.Kidney tumor classification from CT imaging remains challenging due to CT-specific intensity variations, tumor heterogeneity, and limited clinically meaningful interpretability in existing deep learning models. To address these limitations, we propose an Explainable MedAttn-ResNet50 framework that integrates radiology-driven preprocessing, multi-scale feature extraction, and medical attention mechanisms within a unified architecture. The preprocessing pipeline applies radiology-inspired intensity normalization, contrast enhancement, and … …Journal of Computer Science, Vol. 22, Issue 8 · 13 Aug 2026 · 1,120 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Metformin Treatment on Inflammatory Factors and Gut Microbial Diversity in Patients with Type II Diabetes MellitusLei Tong, Jingjing Zhang, Li Xiao Yue et al.With the persistent rise in the prevalence of Type 2 Diabetes Mellitus (T2DM), traditional treatment evaluations have primarily focused on glycemic control, often overlooking the multidimensional effects of medications. As a first-line therapeutic agent, the anti-inflammatory effects and gut microbiota regulation mechanisms of metformin remain incompletely elucidated. This prospective cohort study established a metformin treatment group and a T2DM control … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 20 Jul 2026 · 774 accessesView PDFCite
Research ArticleOpen accessIn the abstractApplication of Machine Learning for the Detection of Depression and Mindfulness as a Mitigation MethodSantiago Domingo Moquillaza Henriquez, Liliana Ruth Huamán Rondón et al.Depression is a global mental health problem with various causes. Nowadays, with Artificial Intelligence, it can be predicted in order to take preventive measures, whether at a psychotherapeutic or pharmacological level. This research, based on a survey conducted, detects depression using logistic regression with a 91% fit to the ROC-AUC model, accuracy of 0.839188, precision 0.851354. In addition, a study … …Journal of Computer Science, Vol. 22, Issue 6 · 16 Jun 2026 · 1,216 accessesView PDFCite
Research ArticleOpen accessIn the abstractHybrid CNN-Based Transformer Pipeline With Radiomic Fusion for Multi-Class Lung Cancer DetectionAanchal Vij, Kuldeep Singh Kaswan, Anand NayyarEarly detection of lung cancer remains challenging due to high intra-class variation and inter-class similarity in Computed Tomography (CT) images. In this paper, we propose a hybrid deep learning model that combines convolutional, attention-based, and transformer-guided representations to address these challenges in multi-class lung cancer classification. For deep feature extraction, we use the EfficientNetV2-S architecture augmented with a Convolutional Block … …Journal of Computer Science, Vol. 22, Issue 6 · 3 Jun 2026 · 1,528 accessesView PDFCite
Research ArticleOpen accessIn the abstractUncertainty-Aware Ensemble Models for Improved Defect Detection in Noisy DataMadhavi Perla, Gadi Lava Raju, A Radha Krishna et al.Software defect prediction plays a crucial role in ensuring software quality and reliability, especially as modern systems become more complex and data rich. This study introduces an uncertainty-aware ensemble learning framework aimed at improving defect classification performance in noisy and imbalanced datasets, particularly those from the PROMISE and NASA KC1 repositories. The proposed model integrates multiple classifiers in a multi-learner … …Journal of Computer Science, Vol. 22, Issue 4 · 27 Apr 2026 · 1,542 accessesView PDFCite
Research ArticleOpen accessIn the abstractHybrid Deep Learning Model for Evaluating Subjective Answers Based on Semantic Textual SimilaritySiddhesh Kudtarkar, Kavita ShirsatSubjective answer evaluation requires accurately identifying semantic similarities between student and reference responses. This study introduces a Hybrid Deep Learning Model (HDLM) that integrates CNN, GRU, and LSTM architectures to assess Semantic Textual Similarity (STS) more effectively. The HDLM employs two parallel branches-CNN-GRU and CNN-LSTM to capture both local syntactic features and long-range contextual dependencies, followed by Manhattan distance for … …Journal of Computer Science, Vol. 22, Issue 4 · 7 Apr 2026 · 1,690 accessesView PDFCite