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27 articles for “surface protein”
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Research ArticleOpen accessIn the abstractDIFFERENT APPROACHES TO CRYSTALLIZATION OF MEMBRANE PROTEINSPrakash G. Doiphode, Vivek Pratap SinghCrystallography is more like an art than science. Crystallizing membrane proteins are a big challenge; membrane proteins are present in the cell membrane and serve as cell support. The most important feature of membrane protein is that it contains both hydrophobic and hydrophilic regions on its surface. They are generally much more difficult to study than soluble proteins. The problem … …OnLine Journal of Biological Sciences, Vol. 12, Issue 3 · 18 Dec 2012 · 7,291 accessesView PDFCite
Research ArticleOpen accessIn the abstractCharacteristic Study of the Marine Algae Sargassum sp. on Metal AdsorptionA. Saravanan, V. Brindha, Soundarajan KrishnanProblem statement: Biomass of brown marine macro algae is a biological resource that is available in large quantities and can form a good base for the development of biosorbent material. Approach: Algae have been found to be potentially suitable biosorbents because of its cheap availability, both in fresh or salt water, relatively high surface area and high binding affinity. Results: … …American Journal of Applied Sciences, Vol. 8, Issue 7 · 24 Jun 2011 · 7,666 accessesView PDFCite
Research ArticleOpen accessIn the abstractRal-Binding Protein is Required for the Maturation and Function of Dendritic CellsJozef Borvak, Mukesh Sahu, Varun Joy et al.Problem statement: Dendritic Cells (DCs) integrate responses of innate and adaptive immune system via transmitting pro-inflammatory and regulatory signals to naïve cells within draining lymph nodes. DCs have high capacity for endocytosis, both Clathrin-Dependent (CDE) and Caveolin-Dependent (CvDE). Approach: We have recently shown that ATP-hydrolysis by the multifunctional transporter protein RLIP76 is the primary determinant of the rate of CDE. … …American Journal of Immunology, Vol. 6, Issue 3 · 13 Sep 2010 · 8,098 accessesView PDFCite
Research ArticleOpen accessIn the abstractSurface Modification of Polystyrene Beads by Ultraviolet/Ozone Treatment and its Effect on Gelatin CoatingA. N. Yusilawati, M. Maizirwan, M. S. Hamzah et al.Problem statement: Polystyrene failed to provide any reactive functionality of surface hydrophilicity that is capable of binding proteins. It is known that polystyrene must be chemically modified to make its surface amenable to covalent crosslinking with protein. Approach: The aim of this study was to investigate the effects of UV/ozone treatment on gelatin coating. The surfaces of microsize polystyrene beads … …American Journal of Applied Sciences, Vol. 7, Issue 6 · 30 Jun 2010 · 8,852 accessesView PDFCite
Research ArticleOpen accessIn the abstracttNOX (ENOX2) Target for Chemosensitization-Low-Dose Responses in the Hormetic Concentration RangeD. James Morre, Sara Dick, Elena Bosneaga et al.An emerging concept of cancer chemotherapy is that of chemosensitization. Most often applied to the treatment of drug-resistance cancers, chemosensitization has utility when such cancers are rendered drug sensitive through treatment with the sensitizing agent. A particularly striking example of chemosensitization is that encountered with the synthetic isoflavene phenoxodiol where patients with taxane- and/or platinum-resistant ovarian carcinoma once again become … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,573 accessesView PDFCite
Research ArticleOpen accessIn the abstractC-Terminal Region of Dengue Virus Nonstructural Protein 1 Is Involved in Endothelial Cell Cross-Reactivity via Molecular MimicryShu-Wen Wan, Chiou-Feng Lin, Mei-Chun Chen et al.Infection with dengue virus (DV) causes diseases ranging from self-limited dengue fever to life-threatening dengue hemorrhagic fever and dengue shock syndrome. Vascular leakage, thrombocytopenia and bleeding are the clinical manifestations associated with dengue hemorrhage. We previously showed that anti-DV nonstructural protein 1 (NS1) antibodies (Abs) cross-reacted with endothelial cells. The potential target proteins on endothelial cell surface recognized by anti-DV … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,564 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptimization of Hydrolysis Conditions for the Production of Iron-Binding Peptides from Scad (Decapterus maruadsi) Processing ByproductsWenting Zhang, Yanan Li, Jie Zhang, Guangrong HuangThe scad (Decapterus maruadsi) processing byproduct (SPB) was hydrolyzed by four commercial enzymes, namely, trypsin, flavourzyme, protamex and alcalase, for preparing high Iron-Binding Capacity (IBC) hydrolysate. Alcalase was the best choice for obtaining high IBC hydrolysate from SPB. Response surface methodology using a central-composite design was employed to optimize the enzymatic hydrolysis conditions with alcalase to obtain a maximum hydrolysate … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 4 · 17 Oct 2016 · 7,591 accessesView PDFCite
Research ArticleOpen accessIn the abstractIgG Subclass Variation of a Monoclonal Antibody Binding to Human Fc-Gamma ReceptorsRekha Patel, Krista K. Johnson, Bruce A. Andrien, Paul P. TamburiniThe importance of human Fc receptors in immune regulation is well known. Their role is critical not only in the recruitment of cellular effector functions but also in regulating the balance in the periphery between autoimmunity and tolerance. Despite their central importance, there is a dearth of literature on controlled numeric comparisons in affinities of antibody subclasses for gamma receptors. … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 8,070 accessesView PDFCite
Research ArticleOpen accessIn the abstractHydroxyl Radical-Scavenging Activity-Guided Extraction of Peptides from Oviductus ranaeJieyang Shen, Yihui Liu, Jiahao Xu et al.Oviductus Ranae (OR) is a traditional Chinese medicinal material that is listed in Chinese Pharmacopeia with proteins the most abundant ingredients. In present work, pepsin/trypsin-based stepwise hydrolysis was applied to extract Antioxidant Peptides from OR (APOR) using hydroxyl radical-scavenging capacity as evaluation index. After single-factor experiment, response surface method coupled with Box-Behnken design were used for optimizing process parameters and … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 4 · 18 Oct 2021 · 6,614 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification a Novel Raw-Starch-Degrading-α-Amylase from a Tropical Marine BacteriumZeily Nurachman, Alfredo Kono, Ocky Karna Radjasa, Dessy NataliaProblem statement: Bacteria from the surface of the tropical marine hard coral Acropora sp. were screened for producing raw-starch-degrading-α-amylase. Approach: Based on its 16s rDNA sequence, a bacterium that produced the highest amylolitic activity was identified as Bacillus amyloliquifaciens ABBD. The bacterial isolate secreted a α-amylase extracellularly and then the enzyme was partially purified by ammonium sulfate precipitation followed by … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 4 · 31 Dec 2010 · 9,337 accessesView PDFCite