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Review ArticleOpen accessIn the abstractRole of HDL in Atherogenesis: Cholesterol and AtheroprotectionAnastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Victor Yurievich Glanz et al.Atherosclerosis is a major global health burden, responsible for a significant proportion of cardiovascular morbidity and mortality worldwide. Its high prevalence and severe clinical consequences have made it a subject of extensive research. Despite considerable advances, the complexity of its pathogenesis continues to hinder the development of effective preventive strategies and therapeutic interventions. Current evidence implicates chronic inflammation, dysregulated lipid … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 3 Apr 2026 · 1,476 accessesView PDFCite
Research ArticleOpen accessIn the abstractAuto Weight Dilated Convolutional Ensemble Network for the Severity Analysis of Lung Cancer in CT ImagesL. Sandhya, K. MarimuthuLung cancer is one of the world's leading causes of morbidity and mortality; improving patient outcomes requires an early and precise diagnosis. Lesion and tumor segmentation remains a challenging task in CT images due to their inherent imaging limitations, such as the small size of nodules, heterogeneous textures, blurry boundaries, and adjacent structures, leading to misclassification and difficulty in delineating … …Journal of Computer Science, Vol. 22, Issue 1 · 9 Feb 2026 · 1,541 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of an IgY-Based Immunomodulatory Combo on the Internalization of Staphylococcus aureus by HC11 Cells: Preliminary in vitro Studies IIZarete Jatna Isha, Adu-Addai BenjaminInfectious mastitis is a common disease of cattle of economic significance. Clinical mastitis affects between 20 to 25% of dairy cows each year. Staphylococcus aureus (SA) causes an estimated 10-11.7% of bovine infectious mastitis cases in the US, reducing milk production, increasing morbidity, increasing antibiotic use and milk waste, and fueling premature culling. The SA mastitis cure rate varies from … …American Journal of Infectious Diseases, Vol. 21, Issue 1 · 1 Feb 2026 · 2,814 accessesView PDFCite
Research ArticleOpen accessIn the abstractEpidemiological Insights and Case Fatality Analysis of SARS-CoV-2 in Indian States During the First WaveRakesh Kaushik, Nikita et al.Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has globally spread, causing a significant health crisis. India, with over 157,000 fatalities, ranks third globally in mortality cases. While vaccine development has played a pivotal role in decelerating the virus's spread, understanding the specific factors influencing morbidity and mortality during the first wave remains essential. This retrospective study analyzes data from 28 Indian … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 21 Jan 2025 · 4,308 accessesView PDFCite
Research ArticleOpen accessIn the abstractBacterial Resistance in Primary Bloodstream Infections in the COVID-19 Pandemic: What has Changed at a Reference Hospital in Northeastern Brazil?Jonathan Da Silva Xavier, Jorge Luiz Nobre Rodrigues, Caroline Mary Gurgel Dias Florêncio et al.The increased use of central venous catheters due to the severity of COVID-19 cases and the difficulty in implementing preventive Healthcare-Associated Infection measures contributed to worsening an already challenging scenario of bacterial resistance. Characterizing the impact of these significant health crises on the bacterial resistance profile is necessary to strengthen antimicrobial control protocols in an effort to decrease morbidity. Our … …American Journal of Infectious Diseases, Vol. 20, Issue 2 · 4 Sep 2024 · 5,033 accessesView PDFCite
Literature ReviewOpen accessIn the abstractThe Relationship between Obesity, Insulin Resistance and Hypertension: A ReviewMasah Mardini, Lana Dardari, Maher Taha et al.Obesity is considered a global epidemic with detrimental health effects. It is linked to the development of conditions such as diabetes mellitus, hypertension, hyperlipidemia, coronary heart disease, atherosclerotic cerebrovascular disease, and higher mortality rates, among other conditions. This review elucidates the pathophysiology linking obesity, insulin resistance, type 2 diabetes, and hypertension and includes clinical trials that demonstrate these relationships. Electronic … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 16 Aug 2024 · 5,076 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Comparative Analysis of TSH Levels between Patients with Normal Sinus Rhythm and those with Atrial FibrillationJi Yeon Chang, Jae Kyung Kim, Seung Hee HongAtrial Fibrillation (AF) is the most prevalent persistent cardiac arrhythmia observed within the general population and is associated with increased morbidity and mortality. Despite the rising global prevalence of AF, the majority of existing studies have primarily focused on white populations. For that reason, we have used a Korean hospital patient's blood test results to examine the link between AF … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 3 · 30 Jul 2024 · 4,476 accessesView PDFCite
Review ArticleOpen accessIn the abstractOverview of the Most Popular Currently Used Murine Models of AtherosclerosisAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Alexandra Alexandrovna Melnichenko et al.Atherosclerosis is a widespread and serious problem. Every year it causes a huge number of deaths and morbidity. Many aspects of this disease remain not fully understood, which indicates the need to search for the most representative model of atherosclerosis in animal and cell culture models. Animal models resembling the pathophysiology in humans are needed to study the immunometabolic mechanisms … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 4 Jan 2024 · 4,669 accessesView PDFCite
Research ArticleOpen accessIn the abstractEarly Responses of Neural Cells (U87) to Particulate Matter Exposure: Cell Viability and Cytokine ConcentrationJae-Sik Jeon, Eun Ju Oh, Qian-Wen Wang, Jae Kyung KimParticulate Matter (PM) has a significant impact on human health and increases the risk of respiratory diseases. PM exposure is linked to various illnesses, including cardiovascular diseases, cancer, neurological diseases, and pregnancy complications, and contributes to both mortality and morbidity globally. PM can also influence the autonomic nervous system. The evidence suggests that the likelihood of developing lung cancer continually … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 20 Feb 2023 · 5,450 accessesView PDFCite
Research ArticleOpen accessIn the abstractNon-Antibiotic Immunomodulatory Combination Treatment for Staphylococcus aureus Infections: In vitro Preliminary Studies IJatna Isha Rivas Zarete, Dominique Lyles, Benjamin Adu-AddaiDespite advancements in prevention measures, infectious mastitis is a common disease of economic significance in cattle. Clinical mastitis affects 20 to 25% of cows each year. Staphylococcus aureus (S. aureus) causes an estimated 10-11.7% of clinical bovine infectious mastitis cases in the US. Antibiotic therapy tends to fail 50% of the time and nature and vaccine immunity usually fails, due … …American Journal of Infectious Diseases, Vol. 18, Issue 4 · 14 Feb 2023 · 5,677 accessesView PDFCite