38 articles for “inhibitory compounds”

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Research ArticleOpen accessIn the abstractEvaluation of Antioxidant and Antibacterial Activities of the Polysaccharides from Mycelium and the Culture Medium of Pleurotus Eryngii Strain UN-1Qing Liu, Haodong Wu, Ying Wu et al.Pleurotus eryngii was one of the most precious and ordinary edible mushrooms, and its polysaccharides were the major active substances. In this study, P. eryngii strain UN-1 was cultured in a liquid medium at 25℃ under a shaking of 80 rpm for 7 days. Two crude polysaccharides named CPN and CPNM were obtained from the mycelium of P. eryngii UN-1 … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 3 · 19 Jul 2022 · 6,176 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAntibacterial Activity of Aqueous and Ethanol Extracts of Caesalpinia Sappan L. against Coagulase-Negative Staphylococci Isolated from Subclinical Bovine and Caprine MastitisDuangjai Boonkusol, Janejira Detraksa, Kansuda DuangsrikaewThis study aimed to investigate the effect of Caesalpinia sappan L. hearth wood extract against Coagulase-Negative Staphylococci (CNS) causing subclinical mastitis in dairy cows and goats. Seventeen and thirty CNS isolates were isolated from bovine and caprine mastitis samples, respectively. The phytochemicals tests performed on aqueous and ethanol extracts of C. sappan heartwood presented total phenolic (150 and 187 mg … …OnLine Journal of Biological Sciences, Vol. 22, Issue 2 · 30 May 2022 · 5,705 accessesView PDF Cite

Research ArticleOpen accessIn the abstractOptimization of Ultrasonic-Assisted Total Flavonoids Extraction from Flower of Albizia Julibrissin Durazz. by Response Surface Methodology for Characterization of Chemical Profile and Evaluation of Antioxidant and Tyrosinase Inhibitory ActivitiesYijie Cheng, Yuwen Zhang, Hanzhang Sun et al.To investigate the flavonoids in flower of Albizia julibrissin (‘He Huan Hua’ in Chinese), the ultrasonic-assisted extraction of total flavonoids from ‘He Huan Hua’ was optimized by response surface methodology and the chemical profile was characterized by HPLC- QTOF-MS/MS. What’s more, the antioxidant and tyrosinase inhibitory activities of ‘He Huan Hua’ were also evaluated in this study. The extraction time, … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 14 Mar 2022 · 6,733 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAqueous Extracts of Bay Leaf (Laurus nobilis) and Rosemary (Rosmarinus officinalis) Inhibit Iron-Induced Lipid Peroxidation and Key-Enzymes Implicated in Alzheimer’s Disease in Rat Brain-in VitroAyodeji O. Falade, Goodness I. Omolaiye, Kayode E. Adewole et al.Neurological disorders remain a global health challenge, with Alzheimer’s Disease (AD) as the most famous cause of dementia in old people. Nevertheless, culinary spices and herbs have shown promising potentials in the management of neurological diseases. This study aimed at investigating the neuroprotective property of aqueous extracts of bay leaf (Laurus nobilis) and rosemary (Rosmarinus officinalis) by assessing the antioxidant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 25 Jan 2022 · 7,955 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAnalysis of Constituents and Bacteriostatic Activity of Essential Oil Extracted from Sea Buckthorn Seeds by Different MethodsHepeng Zhao, Fuyin Zhao, Qian Xiao et al.Sea buckthorn is a homologous plant listed in Chinese pharmacopoeia. The Essential Oils (EOs) of Sea Buckthorn Seeds (SBTS) are widely used in medicine and health products in China, Russia and other countries. The extraction methods of SBTS with advantages of low cost, high yield and high activity have attracted considerable attention. In this study, the extraction rate, chemical compositions … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 2 · 4 Jun 2021 · 7,480 accessesView PDF Cite

Research ArticleOpen accessIn the abstractChemical Constituents, Antibacterial and Coagulation Activity of the Essential Oil from the Stem of Artemisia argyle H. Lév.Jiale Shan, Hongli ZhouArtemisia argyle H. Lév. (A. argyle) is a plant of historical importance known as the "mother of herbs" in the Middle Ages. As the leaves of A. argyle have been studied more, but the stems has not been reported. This paper explores the chemical constituents, antibacterial and coagulation activities of the Essential Oil from the Stems of A. argyle (EOSAA) … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 2 · 31 May 2021 · 6,428 accessesView PDF Cite

Research ArticleOpen accessIn the abstractQSAR Modeling of Thirty Active Compounds for the Inhibition of the Acetylcholinesterase EnzymeNour El Houda Hammoudi, Yacine Benguerba, Widad SobhiThis work aims at developing a reliable and predictive QSAR model which allows, on one hand, an exploration of the main molecular descriptors responsible for the inhibitory activity towards the Acetylcholinesterase enzyme and, on the other hand, predict the inhibitory activity of new compounds before testing them experimentally. This study involves a series of DL0410 and its 29 DL0410 derivatives. … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 2 Mar 2020 · 11,426 accessesView PDF Cite

Research ArticleOpen accessIn the abstractHighlight of New Phosphodiesterase 10A Inhibitors Using Molecular DockingHalla Belhoula, El Hassen Mokrani, Abderrahmane Bensegueni, Djihane BioudPhosphodiesterase 10A (PDE 10A) is an effective therapeutic approach for treatments of Schizophrenia (SCZ). In order to identify in silico new potent PDE 10A inhibitors, molecular docking approach was used. In this context, the compound S235 was predicted to exhibit a high potential PDE 10A inhibitory activity among 369 compounds tested. The predicted binding energy of this compound was improved … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 6,701 accessesView PDF Cite

Research ArticleOpen accessIn the abstractTotal Phenolic, Resveratrol Content, Antioxidant and Antimicrobial Activity in Five Cultivars of Peanut SproutsQing Liu, Shaoqi Li, Yao Zhang et al.Peanut sprout is one of the potential natural sources of bioactive substances. In this study, five different peanut cultivars were conducted to germination, the change in total phenolic compounds, resveratrol content, antioxidant and antimicrobial activity were investigated. The sprouts of five peanut cultivars (Fuhua, Silihong, Dabaisha, Xiaobaisha and Huayu) were extracted using 75% ethanol for 3 h and the crude … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 1 · 12 Feb 2020 · 8,546 accessesView PDF Cite

Research NotesOpen accessIn the abstractThe Phytol-rich Essential Oil from Fresh Medicago hispida Exerts Significant Inhibitory Activity against Escherichia coliLixue Zheng, Leijie Ben, Zhumei Cui et al.Medicago hispida is one of the most widely distributed and commonly cultivated plants of the genus Medicago in China. It is mainly consumed as a vegetable. In this paper, the extraction, chemical composition and antimicrobial potential of the essential oil from fresh M. hispida (EOFMH) were conducted and evaluated for the first time. The extraction yield of EOFMH was found … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 4 · 28 Dec 2019 · 7,355 accessesView PDF Cite