Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

64 results for “bioinformatics”
Set a search alert
Research ArticleOpen accessIn the keywordsThe Relevance of Bioinformatic Tools in the Study of Polymorphisms of the B4GALNT2 Gene and its Association with CancerEddaikra Atika, Haddouche Hayet, Touil-Boukoffa ChafiaThe human gene B4GALNT2 encodes an enzyme (β1,4-N-acetylgalactosaminyltransferase II) that controls the expression of the blood group Sda carbohydrate’s antigen. This gene is located in position 17q21,32 and consists of 11 exons. The characterization and understanding of genetic variation is a real challenge in human genetics, both for healthy individuals and diseased ones. The in silico study of the B4GALNT2 … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 6,773 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPerformance Improvement of SNP Search Using Multithread ProgrammingGeraldo Francisco Donegá Zafalon, Álvaro Magri Nogueira da Cruz, Anderson Rici Amorim et al.Pattern recognition is an important field in Bioinformatics and a well-known task is the search for Single Nucleotide Polymorphism (SNP). It is possible to search for a known SNP position and analyze it using patterns of DNA bases, called masks. Nonetheless, this process becomes computationally expensive as the amount of available genomic data increases. Thus, in this study, we have … …Journal of Computer Science, Vol. 14, Issue 11 · 7 Nov 2018 · 7,738 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIn silico Analysis of 4CL Family in Scutellaria baicalensis through Biocomputational Tools and ServersGuoming Li, Xiaozhong Lan, Xiaorong Shui et al.The gene sequences of 4-coumarate:coenzyme A ligase (4CL) family of Scutellaria baicalensis came from the GenBank Database. With help of some bioinformatics tools such as Vector NTI Suite 8, ProtParam and SWISS-MODEL and so on, a series of biological information of their nucleic acid sequences and amino acid sequences were predicted and analyzed and the results were revealed as following: … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 1 · 15 Feb 2017 · 7,866 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA Survey of Compute Intensive Algorithms for Ribo Nucleic Acids Structural DetectionRa’ed Al-Khatib, Rosni Abdullah, Nur’Aini Abdul RashidProblem statement: Finding an accurate RNA structural alignment from primary sequence due to it is time consuming and computationally NP-hard problem is a major bioinformatics challenge. According to our investigation majority of current researches were concerned on achieving faster execution time, improving space complexity and better cache management. Recently one research introduced cache-efficient Chip Multiprocessor (CMP) algorithms with good speed-up … …Journal of Computer Science, Vol. 5, Issue 10 · 31 Oct 2009 · 6,463 accessesView PDFCite
Research ArticleOpen accessIn the keywordsTaxonomically Clustering Organisms Based on the Profiles of Gene Sequences Using PCAE. Ramaraj, M. PunithavalliThe biological implications of bioinformatics can already be seen in various implementations. Biological taxonomy may seem like a simple science in which the biologists merely observe similarities among organisms and construct classifications according to those similarities[1], but it is not so simple. By applying data mining techniques on gene sequence database we can cluster the data to find interesting similarities … …Journal of Computer Science, Vol. 2, Issue 3 · 31 Mar 2006 · 6,753 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA Selection-based MCL Clustering Algorithm for Motif DiscoveryChunxiao Sun, Zhiyong Zhang, Jinglei Tang, Shuai LiuAs motif discovery plays an important role in the understanding of the relationship of gene regulation, this paper puts forward a selection-based MCL clustering refinement algorithm (SMCLR) aiming at solving the planted (l, d) motif search (PMS) problem. Firstly, we divide the DNA dataset into different subsets through selection of reference sequence and screen parts of eligible subsets by setting … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 4 · 1 Jan 2019 · 8,830 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHomology Modeling of Buffalo (Bubalus bubalis) Interferon-Tau ProteinIndu Joshi, Sunil Kumar, Arminder Kaur et al.Interferon-Tau (IFNt) contributes towards maternal recognition of pregnancy in ruminants (like, cattle, buffalo, goat, giraffe). IFNt has been extensively studied in most of the ruminants except for buffalo Bubalus bubalis). The present study has been undertaken to predict the secondary structure of Interferon-tau in buffalo. The available amino acid sequence of bubaline IFNt (sequence database of SwissProt) was subjected to … …Current Research in Bioinformatics, Vol. 2, Issue 1 · 2 Jan 2018 · 7,526 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIn silico Analysis of three Committed-Steps Involved in Triterpenoid Biosynthesis from Ganoderma lucidumXiaorong Shui, Xiaozhong Lan, Wei LeiGanoderma lucidum is widely considered as one of the most valuable Traditional Chinese Medicines, with various bioactive constituents and pharmaceutical effects. Triterpenoids are important effective ingredients of G. lucidum, which are synthesized mainly through the mevalonate pathway. In this study, we aimed to characterize and analyze three committed-step enzymes of the mevalonate pathway, 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGR), Farnesyl Diphosphate Synthase … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 3 · 15 Aug 2016 · 7,349 accessesView PDFCite
Research ArticleOpen accessIn the keywordsApplying Information Theory Analysis for the Solution of Biomedical Data Processing ProblemsDavid Blokh, Ilia StamblerThe use of information-theoretical methods can be highly valuable for the solution of biomedical data processing problems. Some of the problems that can be solved by those methods include: The assessment of the influence of diagnostic parameters, biomarkers and risk factors, on the emergence of disease; the discretization of diagnostic parameters; the analysis of a combined influence of a group … …Current Research in Bioinformatics, Vol. 3, Issue 1 · 13 Jan 2015 · 9,638 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHomology Modeling of Buffalo (Bubalus bubalis) Interferon-Tau ProteinIndu Joshi, Sunil Kumar, Arminder Kaur et al.Interferon-tau (IFNt) contributes towards maternal recognition of pregnancy in ruminants (like, cattle, buffalo, goat, giraffe). IFNt has been extensively studied in most of the ruminants except for buffalo Bubalus bubalis). The present study has been undertaken to predict the secondary structure of Interferon-tau in buffalo. The available amino acid sequence of bubaline IFNt (sequence database of SwissProt) was subjected to … …Current Research in Bioinformatics, Vol. 1, Issue 2 · 17 Apr 2013 · 7,008 accessesView PDFCite