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64 results for “bioinformatics”
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Research ArticleOpen accessEvery word in the titleBioInfoKnowledgeBase: Comprehensive Information Resource for Bioinformatics ToolsRatna Prabha, D. P. Singh, Anil RaiBioinformatics is revolutionizing biological sciences and facilitating every area of biology. Right from the start of any biological project, information regarding availability of resources or databases appropriate for the analysis of data repository are becoming essentially required. Biological scientists use to browse across the web for searching tools/softwares and to identify most appropriate one for analysis purpose. Time of any … …Current Research in Bioinformatics, Vol. 4, Issue 2 · 24 Aug 2015 · 7,034 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleTen Bioinformatics Tools for Single Nucleotide Polymorphisms DetectionMahin Ghorbani, Hamed KarimiSingle Nucleotide Polymorphisms (SNPs) as unique genetic variations are widely used as biomarkers for drug designing and development for individualized therapy. SNP genotyping techniques such as SBE with MS detection, SBE with fluorescence intensity detection, The FP-TDI, Pyrosequencing and The TaqMan 5’ nuclease assay are low-speed, time consuming and very expensive. To overcome such disadvantages, bioinformatics tools are emerged as … …Current Research in Bioinformatics, Vol. 3, Issue 2 · 10 Apr 2015 · 17,728 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAn Efficient Distributed Bioinformatics Computing System for DNA Sequence Analysis on Encoding SystemMohammad Ibrahim Khan, Chotan SheelThis study provides an effective design of search technique of a distributed bioinformatics computing system for analysis of DNA sequences using OPTSDNA algorithm. This system could be used for disease detection, criminal forensic analysis, gene prediction, genetic system and protein analysis. Different types of distributed algorithms for the search and identification for DNA segments and repeat pattern in a given … …Current Research in Bioinformatics, Vol. 2, Issue 2 · 20 Dec 2013 · 6,931 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBioinformatics-Assisted Microbiological Research: Tasks, Developments and Upcoming ChallengesDhananjaya P. Singh, Ratna Prabha, Anil Rai, Dilip K. AroraProblem statement: Bioinformatics in the present day microbiological research is an inevitable subject area that encompasses biological resources and high end computational skills to unravel the coded and encrypted information within the life. We have produced a brief account of the developments and tasks in the subject and upcoming challenges in the subject. The area has seen tremendous developmental pattern … …Current Research in Bioinformatics, Vol. 1, Issue 1 · 23 Jan 2012 · 14,793 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleUPLC-QTOF-MS/MS and Bioinformatics Association Analysis Reveals the Pharmacodynamic Flavonoids in Scutellaria barbata and the Underlying Anti-Colorectal Cancer MechanismYi-Jie Cheng, Xin-Yun Du et al.Colorectal Cancer (CRC) is one of the most common and deadly malignancies worldwide, with no safe and effective drugs. The flavonoid in Scutellaria Barbata D. Don (SB) showed a good therapeutic effect on CRC. However, the pharmacodynamic substances and underlying mechanisms have not been elucidated which limited its development and application. This study aimed to identify the main flavonoid in … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 14 Nov 2023 · 5,398 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBioinformatics Analysis of Some Functional Genes and Proteins Involved in Obesity-Induced Type 2 DiabetesEhab M. Abdella, Rasha R. Ahmed, Mohamed B. Ashour et al.The incidence of type-2 diabetes is rising rapidly worldwide, mainly because of the increase in the incidence of obesity, which is an important risk factor for this condition. Both obesity and type-2 diabetes are complex genetic traits but they also share some nongenetic risk factors. Differences among individuals in their susceptibility to both these conditions probably reflect their genetic constitutions. … …Current Research in Bioinformatics, Vol. 1, Issue 2 · 6 May 2013 · 12,601 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBioinformatics Analysis of Xyloglucan Endotransglycosylase/Hydrolase (XTH) Gene from Developing Xylem of a Tropical Timber Tree Neolamarckia CadambaTiong Shing Yiing, Ho Wei Seng, Pang Shek Ling, Ismail JusohThis study reported the isolation and in silico characterization of a full-length Xyloglucan endotransglycosylase/Hydrolase (XTH) cDNA from Neolamarckia cadamba, an important tropical light hardwood plantation tree species. XTH is considered as a key agent to regulate cell wall expansion and is believed to be responsible for the incorporation of newly synthesised xyloglucan into the wall matrix. The full-length of NcXTH … …Current Research in Bioinformatics, Vol. 3, Issue 1 · 6 Jan 2015 · 7,426 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIdentification of SBP Gene Family and Analysis of Expression Patterns Under Salt Stress in QuinoaWeihai Hou, Jianlin Wang, Zongyu Zhang et al.This study aimed to identify the Squamosa promoter Binding Protein (SBP) transcription factor from the whole genome of quinoa by analyzing its phylogenetic relationship, gene structure, chromosome location, gene replication, upstream cis-regulatory elements, tissue expression, and construction of the SBP protein interaction network, as well as the characteristics of its tissue expression pattern under salt stress. The researchers found that … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 21 Mar 2023 · 5,503 accessesView PDFCite
Review ArticleOpen accessIn the keywordsBig Data and its Future in Computational Biology: A Literature ReviewIman Ahmed ElSayed, Kamal ElDahshan, Hesham Hefny, Eman Karam ElSayedBig data technologies are used majorly for computational biology research nowadays due to the emerge of massive amounts of biological data that have been generated and collected at an unprecedented speed and scale and with different structures. As an example, the processing of billions of DNA sequence data per day represents the new generation of sequencing technologies. It is expected … …Journal of Computer Science, Vol. 17, Issue 12 · 31 Dec 2021 · 6,598 accessesView PDFCite