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39 articles for “bioassay”
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Research ArticleOpen accessIn the abstractAcaricidal Activity of Azadirachta indica (Neem Tree) and Carica papaya (Papaya) Leaf Extracts against Rhipicephalus sanguineus (Dog Ticks) Using Spray MethodAlfredo Vita Corpuz, Carmela Montoya Florentino, Paul Erman Tabuloc Quilana et al.Ticks pose a serious threat to dogs, with synthetic acaricides leading to environmental impact and resistance concerns. While Azadirachta indica and Carica papaya have shown acaricidal potential against Rhipicephalus sanguineus, their efficacy against dog ticks has not been thoroughly investigated. This study determined the acaricidal activity of A. indica and C. papaya leaf extract against R. sanguineus, both individually and … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 22 Apr 2025 · 8,409 accessesView PDFCite
Research ArticleOpen accessIn the abstractGadolinium at Low Concentration Suppresses both Osteoclastic and Osteoblastic Activities in the Scales of GoldfishNobuo Suzuki, Kazuki Watanabe, Aika Sekimoto et al.For determining the effect of environmental pollutants on fish bone metabolism, we have developed an in vitro bioassay system using teleost scales that has osteoclasts, osteoblasts and bone matrix as markers: alkaline phosphatase (ALP) for osteoblasts and tartrate-resistant acid phosphatase (TRAP) for osteoclasts. Using this bioassay, the influence of gadolinium (Gd) on osteoclasts and osteoblasts of goldfish scales was examined … …American Journal of Environmental Sciences, Vol. 15, Issue 4 · 20 Sep 2019 · 8,451 accessesView PDFCite
Research ArticleOpen accessIn the abstractLarvicidal Activity of Bruceine A against Aedes aegypti and Toxicity on Vero CellsDwi Sutiningsih, Mustofa, Tri Baskoro Tunggul Satoto, Edhi MartonoVector control is still based on the use of chemical insecticides, which can cause death of nontarget animals, pollution and the emergence of vector resistance. This study aims to assess the larvicidal activity of bruceine A against larvae of Aedes aegypti and its cytotoxic activity against Vero cells. Extraction and isolation of bruceine A from the seeds of Brucea javanica … …OnLine Journal of Biological Sciences, Vol. 18, Issue 3 · 4 Sep 2018 · 7,912 accessesView PDFCite
EditorialOpen accessIn the abstractAMYOTROPHIC LATERAL SCLEROSIS: HOW TO UNDERSTAND SUCH DIVERSE AND SO ENTANGLED PHYSIOPATHOLOGY?Carlos Henrique Melo Reis, Marco Orsini, Marco Antônio Araujo Leite et al.When in 1865, JeanMartin Charcotreported patients with progressive muscular atrophysuperimposedwith spasticity of inexorable evolution as result of combinedlesions of the anterior horn and lateral column of the spinal cord, hecertainly inaugurated an attempt on the comprehension of one of the mostcomplexes neurological clinical conditions, which until today persists withimmense voids on their comprehension, regardless of the enormous advancesachieved. Astime went … …Current Research in Medicine, Vol. 5, Issue 2 · 16 Feb 2015 · 7,149 accessesView PDFCite
Research ArticleOpen accessIn the abstractDEVELOPMENT OF A BACTERIAL CULTURE SYSTEM USING A PAPER PLATFORM TO ACCOMMODATE MEDIA AND AN INK-JET PRINTING TO DISPENSE BACTERIATithimanan Srimongkon, Takuya Ishida, Kiyohiko Igarashi, Toshiharu EnomaeGenerally, bacterial culture is performed manually and is subject to error. Here, we created a novel, well-ordered and reliable system for dispensing bacteria microscopically by using paper and an ink-jet printer for controlled patterning. For paper to accommodate a culture medium, hydrophobic/hydrophilic patterns were incorporated onto the paper by immersing paper in a toluene solution of polystyrene and drying for … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 1 · 26 Apr 2014 · 7,939 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn-Vivo Evaluation of Hexavalent Chromium Induced DNA Damage by Alkaline Comet Assay and Oxidative Stress in Catla catlaKantha Deivi Arunachalam, Sathesh Kumar Annamalai, Jaya Krishna KuruvaIn the present study, the acute toxicity of Chromium in fingerlings of Catla catla, an Indian major carp, was evaluated with renewal bioassay method. In vivo studies were designed to assess the extent of Micronucleus Assay, Comet Assay under the exposure of common heavy-metal compounds, namely, Chromium Nitrate, using Catla catla (2n = 20), as a test model. The laboratory … …American Journal of Environmental Sciences, Vol. 9, Issue 6 · 15 Jan 2014 · 7,196 accessesView PDFCite
Research ArticleOpen accessIn the abstractBio-Guided Study on Melastoma malabathricum Linn Leaves and Elucidation of its Biological ActivitiesMourouge Saadi Alwash, Nazlina Ibrahim, Wan Yaacob AhmadThe present study aimed to isolate and identify constituents with antibacterial activity from the Methanol extract of Melastoma malabathricum leaves (MMML) through bioassay guided fractionation. Furthermore, the study scoped to evaluate the cytotoxic effects of M. malabathricum leaves fractions for possible protective effect of antoxidative constituents present in the fractions. The MMML extract was fractionated by Vacuum Liquid Chromatography (VLC) … …American Journal of Applied Sciences, Vol. 10, Issue 8 · 24 Jul 2013 · 9,513 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification and Characterization of Antibiotic-Producing Actinomycetes IsolatesMeera Kumari, Bat-Erdene Myagmarjav, Birendra Prasad, Madhusudan ChoudharyActinomycetes are a gram-positive, filamentous subgroup of bacteria most known for antibiotic production. In fact, most of the antibiotics available today have originated from actinomycetes, namely from the genus Streptomyces. Novel bacteria with antimicrobial activities have been discovered from bacterial screen studies for decades and there is still much more yet to be unearthed. One hundred seventy five strains of … …Current Research in Microbiology, Vol. 4, Issue 1 · 25 Jun 2013 · 15,437 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification and Mode of Action of Antibacterial Components from Melastoma malabathricum Linn LeavesMourouge Saadi Alwash, Nazlina Ibrahim, Wan Yaacob AhmadThe present study aimed to assess the antibacterial activity of the methanol extract of Melastoma Malabathricum Leaves (MMML), active fraction of M. Malabathricum Leaves (ML5) and isolated kaempferol-3-O-(2",6"-di-O-p-trans-coumaroyl)-β-glucopyranoside (Kf) and to describe the preliminary mode of action against Gram-positive and Gram-negative bacteria. The MMML extract was fractionated by Vacuum Liquid Chromatography (VLC) to afford M. malabathricum Leaves fractions (ML1-ML6) of … …American Journal of Infectious Diseases, Vol. 9, Issue 2 · 18 Jun 2013 · 12,621 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effectiveness of Organotin (IV) Benzylisopropyldithiocarbamate Compounds as Insecticide Against Aedes Aegypti Linn (Diptera: Culicidae) in LaboratoryHidayatulfathi Othman, Nor Atikah Kosnon, Normah Awang, Nurul Farahana KamaludinProblem statement: The widespread use of insecticides had resulted in insecticide resistance of vectors of dengue as well as polluting the environment. Organotin (IV) compounds had the potential to be developed as the insecticides to overcome the existing problem. Approach: The aim of this study was to examine the insecticidal effects which were larvicidal and adulticidal effects of organotin (IV) … …American Journal of Applied Sciences, Vol. 9, Issue 8 · 25 Jun 2012 · 6,980 accessesView PDFCite