The Effectiveness of Organotin (IV) Benzylisopropyldithiocarbamate Compounds as Insecticide Against Aedes Aegypti Linn (Diptera: Culicidae) in Laboratory

Problem statement: The widespread use of insecticides had resulted in insecticide resistance of vectors of dengue as well as polluting the environment. Organotin (IV) compounds had the potential to be developed as the insecticides to overcome the existing problem. Approach: The aim of this study was to examine the insecticidal effects which were larvicidal and adulticidal effects of organotin (IV) benzylisopropyldithiocarbamate compounds against Aedes Aegypti Linn. In laboratory larvicidal bioassay test of a series of three organotin (IV) benzylisopropyldithiocarbamate compounds on third instar larvae of Aedes Aegypti had been carried out. Results: The study was found that compound B showed the best larvicidal effect with the LC₅₀ and LC₉₀ values of 0.004 ppm and 0.007 ppm, respectively. Compound C was also displayed good larvicidal effect with the LC₅₀ and LC₉₀ values of 0.029 ppm and 0.108 ppm, respectively. While, compound A was shown the least larvicidal effect with the LC₅₀ and LC₉₀ values of 0.404 ppm and 0.749 ppm, respectively. Further testing was conducted on compound B on adults of Aedes ageypti female to investigate its adulticidal property. The result showed that compound B displayed good adulticidal activity with LC₅₀ dan LC₉₀ of 4.277 ppm and 27.653 ppm, respectively. Conclusion: Compound B is the most effective compound among three organotin (IV) benzylisopropyldithiocarbamate compounds tested against the dengue vector Aedes Aegypti and has potential to be explored as an insecticide to control the spread of dengue fever.