Research ArticleOpen accessIn the author namesUltrasonic Microwave Assisted Extraction, Chemical Characterization and Antioxidant Activity of Polysaccharides from Fig LeavesBaikangzhe Zheng, Yang Miao, Yi Zhou et al.This study employed ultrasonic-microwave-assisted extraction (UMAE) to isolate water-soluble polysaccharides from fig (Ficus carica L.) leaves (FLPs). Polysaccharide yield was used as the primary index to evaluate extraction efficiency. The effects of material-liquid ratio, microwave power, extraction temperature, and extraction time on polysaccharide yield were systematically investigated through single-factor experiments, followed by response surface methodology optimization. Structural characterization and antioxidant … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 3 Mar 2026 · 1,671 accessesView PDFCite
Research ArticleOpen accessIn the author namesAn AI-Powered Integrated Care Model Combining Traditional Chinese Medicine and Western Medicine for Personalized Alzheimer’s Disease ManagementShurong Li, Yiming Chen, Jin Xu et al.Alzheimer's Disease (AD) gradually reduces memory and cognition. While Western medicine focuses on pharmacological treatments, it frequently ignores holistic factors such as mood and digestion. Traditional Chinese Medicine (TCM) addresses these issues through a wellness-oriented approach. However, the combination of both systems in patient care is uncommon. Current Alzheimer's disease treatments are often siloed, relying solely on Western or alternative … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 16 Feb 2026 · 2,063 accessesView PDFCite
Research ArticleOpen accessIn the author namesExploring the Relationship Between Skin Barrier Function, Sensitivity, and Repair MechanismsXiaoqing Yan, Yusong Shi, Jiguang YangFor healthy skin, the skin's barrier function must remain maintained. Many different molecular while immunological signaling mechanisms are involved in skin barrier control. The control of a healthy skin barrier, particularly acid mantle maintenance and proper amounts of ceramides, may help dermatologists develop remedies for skin barrier disruption disorders. In contrast, new medicines could focus on signaling pathways to offer … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,893 accessesView PDFCite
Research ArticleOpen accessIn the author namesEpigenetic Regulation of Extracellular Matrix Remodeling in Skin Aging: Mechanisms and InteractionsJiguang Yang, Yusong Shi, Xiaoqing YanSkin aging results from complex interactions between genetic factors, environmental stressors, and epigenetic modifications that regulate extracellular matrix (ECM) remodeling. Accumulation of senescent cells impairs tissue regeneration through mechanisms including telomere shortening, reactive oxygen species accumulation, and ultraviolet (UV) radiation exposure. While epigenetic pathways regulate skin homeostasis, regeneration, and senescence, the specific epigenetic changes occurring during UV exposure, chronological aging, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,458 accessesView PDFCite
Research ArticleOpen accessIn the author namesOptimization of α-Glucosidase Inhibitors Recovery from Rainbow Trout Hydrolysate Using GA-BP Neural NetworkYingke Chu, Yanling Dong, Qingfeng Rong et al.To enhance the value of by-products from rainbow trout processing, the inhibition rate of α-glucosidase (AGIR) is used as indicators. Optimization of rainbow trout hydrolysate extraction by comparing Response Surface Methodology (RSM) and BP Neural Network (BPNN) models. The RSM results: the AGIR is 55.02%. BPNN models predicted the optimal extraction conditions: 51℃ for temperature,1:2.3 for solid-liquid ratio, 4.15 h … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 28 Jan 2026 · 1,734 accessesView PDFCite
Research ArticleOpen accessIn the author namesEffects of Different Extraction Methods on the Quality of Peony Seed Oil and Its Emulsion PropertiesKang Li, Chao Du, Shuxian Pang et al.Peony seed oil, as a functional oil rich in ω-3 polyunsaturated fatty acids and natural antioxidant components, has its extraction process directly affecting the maintenance of bioactive substances and the added value of the product. In this analysis, the effects of wet milling-micronized continuous leaching method (MCI), solvent extraction (SE), soxhlet extraction (SOXE) and ethanol-assisted enzymatic hydrolysis (EAH) on the … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 28 Jan 2026 · 1,955 accessesView PDFCite
Research ArticleOpen accessIn the author namesA Design Method of SPEM-based Feature Methodology FrameworkChee-Yang Song, Eun-Sook ChoExisting feature methodologies have been presented primarily at the research level, lacking generalized frameworks suitable for commercial application. Critically, the absence of SPEM (Software & Systems Process Engineering Metamodel) standard compliance limits their standardization and systematization, hindering practical adoption. Furthermore, work-product-based feature methodology frameworks that facilitate methodological structuring are needed to address the evolving complexity of software development processes. This … …Journal of Computer Science, Vol. 21, Issue 11 · 26 Dec 2025 · 1,719 accessesView PDFCite
Research ArticleOpen accessIn the author namesExpression and Induction Optimization of Mucor Circinelloides Lipase in Escherichia ColiYueping Yang, Yao Zhang et al.Microbial lipases serve as versatile biocatalysts for modifying lipid substrates, enabling diverse biotechnological applications spanning food technology, renewable energy production, and pharmaceutical sectors. Genomic analysis of Mucor circinelloides WJ11 revealed multiple lipase-encoding genes, with WJ_23 successfully cloned and heterologously expressed in Escherichia coli. Since the lipase expression was mainly concentrated in the cell pellets, appropriate induction strategies had been investigated … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 13 Jun 2025 · 5,982 accessesView PDFCite
Research ArticleOpen accessIn the author namesStudy on the Enhancement of Hypoglycemic and Antioxidant Activities of Compound Herbal Tea through Solid-State FermentationQing Liu, Xiaowen Que, Yueping Yang et al.This study utilized Aspergillus niger KY2295 for the Solid-State Fermentation (SSF) of a compound tea made from Cinnamomum cassia bark, Glycyrrhiza glabra, Morus abla L. leaf, and Crataegus oxyacantha L. to enhance its hypoglycemic effects. The fermentation process was optimized using single-factor experiments and a Central Composite Design (CCD), with α-amylase and α-glucosidase inhibitory activities as evaluation indices. Following fermentation, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 1 · 20 May 2025 · 5,473 accessesView PDFCite