Sign inSubmit
ArticleMetrics
Research Article · Open access · Published 16 February 2026

An AI-Powered Integrated Care Model Combining Traditional Chinese Medicine and Western Medicine for Personalized Alzheimer’s Disease Management

Shurong Li1, Yiming Chen2, Jin Xu1, Jiayu Zhang3 & Yuntong Yang1

American Journal of Biochemistry and Biotechnology, Volume 21, Issue 4, pp. 630–644 · doi.org/10.3844/ajbbsp.2025.630.644

2,063 accesses1,082 downloads0 citations (Crossref)Metrics
Cite Check for updates

Abstract

Alzheimer's Disease (AD) gradually reduces memory and cognition. While Western medicine focuses on pharmacological treatments, it frequently ignores holistic factors such as mood and digestion. Traditional Chinese Medicine (TCM) addresses these issues through a wellness-oriented approach. However, the combination of both systems in patient care is uncommon. Current Alzheimer's disease treatments are often siloed, relying solely on Western or alternative medicine. A unified, intelligent system is required to capitalize on the advantages of both methods.  This study aims to create an AI-powered model that combines TCM and Western medicine to offer personalized Alzheimer's care, allowing for early diagnosis and improved treatment plans that contain herbs, drugs, and lifestyle recommendations. The proposed AI-Powered Integrated Alzheimer's Care (AIP-IAC) model is based on patient data, including demographics, imaging, lab results, cognitive scores, and treatment history. After preprocessing the patient data, machine learning models such as Random Forest and XGBoost are employed to generate predictions, while clustering algorithms discover unique patient subgroups using similar features. A Long Short-Term Memory (LSTM) tracks symptom progression, and a rule-based TCM engine improves AI recommendations into personalized plans, which are continuously updated using patient feedback. AIP-IAC was tested on 1,200 patients and achieved 91.3% accuracy, with high precision (89.7%), recall (90.2%), and F1-score (89.9%). Over six months, it decreased trial-and-error by 32% while increasing patient quality-of-life metrics like sleep and mood by 25-30%.  Incorporating TCM and Western practices using AI results in more personalized and efficient Alzheimer's care. The AIP-IAC model enhances early detection, treatment precision, and patient well-being

Licence and reuse

Open access. This article is licensed under a Creative Commons Attribution 4.0 International Licence (CC BY 4.0), as printed on the article, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original authors and the source. No permission is needed.

How to reuse this article

Responses (0)

Have a comment on this research? Sign in to respond. Responses are moderated and published with your name and affiliation; the authors are invited to reply. How we use your dataWrite a response

About this article

Cite this article

Li, S., Chen, Y., Xu, J., Zhang, J. & Yang, Y. (2025). An AI-Powered Integrated Care Model Combining Traditional Chinese Medicine and Western Medicine for Personalized Alzheimer’s Disease Management. American Journal of Biochemistry and Biotechnology, 21(4), 630–644. https://doi.org/10.3844/ajbbsp.2025.630.644

Licence
CC BY 4.0
Issue
Volume 21, Issue 4
Policies
Editorial independenceUse of generative AIData availabilityAppeals and complaints
Version
Version of record
An AI-Powered Integrated Care Model Combining Traditional Chinese Medicine and Western Medicine for Personalized Alzheimer’s Disease ManagementAmerican Journal of Biochemistry and Biotechnology · Volume 21, Issue 4 · pp. 630–644 · CC BY 4.0Download