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59 articles for “Tumors”
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Research ArticleOpen accessIn the abstractExplainable MedAttn-ResNet50 for Automated Kidney Tumor Classification from CT Images With Grad-CAM VisualizationD. Vetrithangam, Pramod Kumar, Shilpasree S. et al.Kidney tumor classification from CT imaging remains challenging due to CT-specific intensity variations, tumor heterogeneity, and limited clinically meaningful interpretability in existing deep learning models. To address these limitations, we propose an Explainable MedAttn-ResNet50 framework that integrates radiology-driven preprocessing, multi-scale feature extraction, and medical attention mechanisms within a unified architecture. The preprocessing pipeline applies radiology-inspired intensity normalization, contrast enhancement, and … …Journal of Computer Science, Vol. 22, Issue 8 · 13 Aug 2026 · 1,120 accessesView PDFCite
Research ArticleOpen accessIn the abstractTowards an Explainable Approach: Hybrid Residual Network and SVM for Automated Brain Tumor Detection and ClassificationKamini Lamba, Shalli RaniThe abnormal growth of brain cells leads to tumor formation, which can be fatal if not detected and treated promptly. Given the complexity of brain tumors, early detection is critical in healthcare. Traditional radiology-based tumor detection is prone to human error and delays. Hence, a computer- assisted method is needed for accurate and efficient diagnosis. With the rapid advancements in … …Journal of Computer Science, Vol. 22, Issue 1 · 11 Feb 2026 · 1,427 accessesView PDFCite
Research ArticleOpen accessIn the abstractCuckoo Search Optimized Random Forest for Breast Cancer PrognosisPrasad S. Sase, Debabrata Swain, Shailesh KumarBreast cancer remains a major global health concern due to its high mortality rate, particularly when diagnosis occurs at an advanced stage. Accurate and early differentiation between benign and malignant tumors is therefore critical for improving patient outcomes. Conventional diagnostic practices largely depend on manual assessment and clinical expertise, which may lead to subjective variability in decision-making. To overcome this … …Journal of Computer Science, Vol. 22, Issue 1 · 31 Jan 2026 · 2,098 accessesView PDFCite
Research ArticleOpen accessIn the abstractDeep Learning Approaches for Brain Tumor Diagnosis using Fused Layer AcceleratorMitrabinda Khuntia, Prabhat Kumar Sahu, Swagatika DeviDeep Convolutional Neural Networks (DCNNs) are an emerging field in biomedical processing. Tumor classification is a key stage in the pathology analysis process, and deep learning algorithms for brain tumor categorization have recently shown promising results. However, these approaches often require more storage and more expensive training procedures to input a large number of training variables. To address this issue, … …Journal of Computer Science, Vol. 19, Issue 2 · 19 Jan 2023 · 5,787 accessesView PDFCite
Research ArticleOpen accessIn the abstractLung Cancer Detection Using Regularized Extreme Learning Machine and PCA FeaturesK. Kavitha, Dr. V. Saravana Kumar, V. Bhoopathy et al.When finding abnormalities in target images is time-sensitive, as it is with many cancer tumors, image processing techniques have recently found widespread use across various medical industries to improve images for early detection and treatment stages. In the setting of cancer, where time is of the essence in detecting anomalies within medical imaging, our research takes on further urgency. In … …Journal of Computer Science, Vol. 20, Issue 10 · 5 Aug 2024 · 5,302 accessesView PDFCite
Research ArticleOpen accessIn the abstractEnhanced Postoperative Brain MRI Segmentation with Automated Skull Removal and Resection Cavity AnalysisSobha Xavier P., Sathish P. K., Raju G.Brain tumors present a significant medical challenge, often necessitating surgical intervention for treatment. In the context of postoperative brain MRI, the primary focus is on the resection cavity, the void that remains in the brain following tumor removal surgery. Precise segmentation of this resection cavity is crucial for a comprehensive assessment of surgical efficacy, aiding healthcare professionals in evaluating the … …Journal of Computer Science, Vol. 20, Issue 5 · 19 Mar 2024 · 5,697 accessesView PDFCite
Review ArticleOpen accessIn the abstractMicroRNA-92a: The Administrator of Certain DiseasesZhiyuan Sun, Qing Xu, Xiaoyi Tian et al.MicroRNA-92a (miR-92a) is an evolutionarily conserved noncoding small RNA that can regulate gene expression after transcription. Previous studies have found that miR-92a is overexpressed in many tumors and can regulate numerous tumor suppressor genes negatively, with relevant effects on the development of different tumors, by regulating the DUSP10/c-Jun N-terminal kinase (JNK), phosphatase and tensin homologs (PTEN)/AKT, Wnt and EP4/Notch1 signaling … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 21 May 2020 · 6,494 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Relevance of Bioinformatic Tools in the Study of Polymorphisms of the B4GALNT2 Gene and its Association with CancerEddaikra Atika, Haddouche Hayet, Touil-Boukoffa ChafiaThe human gene B4GALNT2 encodes an enzyme (β1,4-N-acetylgalactosaminyltransferase II) that controls the expression of the blood group Sda carbohydrate’s antigen. This gene is located in position 17q21,32 and consists of 11 exons. The characterization and understanding of genetic variation is a real challenge in human genetics, both for healthy individuals and diseased ones. The in silico study of the B4GALNT2 … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 6,767 accessesView PDFCite
Research ArticleOpen accessIn the abstractIsolation and Identification of Oral Cancer Stem Cells (CSC) within Commercially Available Cell LinesRobert Chauncey, Kai Hatch, Toni Jilka et al.Previous studies have demonstrated some tumors develop or maintain a small sub-population of cells with stem cell-like properties. This Cancer Stem Cells (CSC) may exhibit differential properties that allow their escape from traditional radiation or chemotherapy treatments and may therefore be responsible for cancer recurrence. Few studies have explored this phenomenon among oral cancer cell lines, therefore the objective of … …Current Research in Dentistry, Vol. 9, Issue 1 · 2 Jun 2018 · 12,719 accessesView PDFCite
EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,281 accessesView PDFCite