35 results for “SNP”

Set a search alert

Review ArticleOpen accessIn the keywordsVascular Endothelial Growth Factor: An Overview Across Multiple Disease ConditionsMiriam CanaveseVascular Endothelial Growth Factor (VEGF) is the major player in the regulation of physiological angiogenesis as well as it has also been implicated in pathological angiogenesis, associated with cancers and other conditions, among which psoriasis, autoimmune diseases and visual loss in macular degeneration. Interestingly, three regulatory Single Nucleotide Polymorphisms (rSNPs) in the promoter region of VEGF-A gene have been significantly … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 6 May 2015 · 7,099 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsDistribution of Alleles and Genotypes of ACE2 Gene Polymorphisms (rs2285666 and rs35803318) and Association with COVID-19 Among Populations in KazakhstanAnar Bisseneva, Konstantin Li, Gayane Pogossyan, Valeriya ProtasThere is still no definitive confirmation regarding the association between ACE2 gene polymorphisms and COVID-19. This study was conducted to analyze the distribution of alleles and genotypes of the ACE2 gene rs2285666 and rs35803318 two polymorphisms and their possible association with COVID-19 among two ethnic groups, namely, the Kazakhs and Eastern Slavs, residing within the same geographic area in the … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 31 Oct 2023 · 4,942 accessesView PDF Cite

Literature ReviewOpen accessIn the abstractPhenotypic, Reproductive and Genomic Perspectives on the Status and Research Gaps of South African Bosvelder SheepNhlakanipho Sam Zulu, Khoboso Christine Lehloenya, Khanyisile Hadebe et al.The South African Bosvelder sheep is an emerging composite sheep developed from indigenous Bapedi and commercial White Dorper and Van Rooy sheep. Despite its reported adaptability and production potential under bushveld conditions, the sheep remains scientifically under-characterized and is not formally recognized within national breeding frameworks. This narrative review evaluates the current state of knowledge regarding phenotypic, reproductive, and genomic … …American Journal of Animal and Veterinary Sciences, Vol. 21, Issue 2 · 1 Jul 2026 · 1,242 accessesView PDF Cite

Research ArticleOpen accessIn the abstractBreeding Progress in Mugalzhar Horses: The Irtysh Type as a Model for Meat Production EfficiencyAkimbekov Amin, Uskenov Rashit, Nurgulsim Kaster et al.The Mugalzhar horse breed holds significant value for meat production in Kazakhstan. Developed through targeted selection, the new Irtysh stud type demonstrates outstanding adaptation and productivity, with stallions reaching an average live weight of 486.1 kg and mares 463.4 kg, an increase of up to 73 kg compared to the original group. The coefficient of variation for live weight and … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 3 · 29 Nov 2025 · 2,613 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAlcohol Intubation and Synergistic Effect of Folic Acid and Egg Yolk Powder Solution on Alcohol Dehydrogenase [ADH] Class I Gene Expression and Single Nucleotide Polymorphism Frequency in Parent and Prenatal Alcohol Exposed Wistar RatsAdejoke Olukayode Obajuluwa, Oluyinka Ajibola Iyiola, Joseph Akintade Morakinyo et al.Point mutation detections in alcohol metabolizing genes could unravel molecular targets of gestational alcohol and epigenetic remodeling capacity of maternal nutrition, which underscores growth and health endpoints in Prenatal Alcohol Exposed (PAE) fetuses. gene expression was assayed using sequenced target and internal control gene primers in a two-step thermal cycling process from isolated RNA in purely bred alcohol male and … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 22 Nov 2023 · 4,857 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAssociation Between Cancer Screening Results Using Single Nucleotide Polymorphism and Cancer Incidence Rate in Korean WomenKyung Bae Lee, Jae Kyung KimIn this study, we investigated the usefulness of Single Nucleotide Polymorphism (SNP) testing in assessing cancer susceptibility in women by evaluating correlations between SNP testing results and cancer incidence rates. SNP testing was conducted on blood samples of women who underwent health examinations commissioned by medical institutions in the Republic of Korea in 2017 using real-time polymerase chain reaction with … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 25 Sep 2023 · 4,956 accessesView PDF Cite

Research ArticleOpen accessIn the abstractIdentification of Novel Mutations of AMH Gene in Iraqi Women with Premature Ovarian FailureFarah Amer Abed, Raya E. Maroof, Ulfat Mohammed Ali Al-NakkashAn over all of thirty females experiencing idiopathic POF and thirty controls have been studied and among them only six patients and four control were sent to sequence. The AMH gene fragments AMH1, AMH2 and AMH5 generates 530 bp, 288 bp and 1080 bp respectively were amplified. Fragments were sequenced and the results show six out of eight observed SNPs … …OnLine Journal of Biological Sciences, Vol. 18, Issue 4 · 11 Dec 2018 · 7,250 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Investigation of Organelle Genomes of Extra Nuclear Sunflower Mutants with Variegated PhenotypeIrina Dremuk, Nikolay Kozel, Mariya Logacheva et al.The comparative analysis of complete chloroplast and mitochondrial DNA sequences of the original inbred line 3629 and three extra nuclear mutant lines variegated-1, variegated-15, variegated-17, obtained by the N-nitroso-N-methylurea induced mutagenesis, was done. The studied mutant lines were presented two different phenotypes with diverse chlorophyll content: Pale/green mutant line variegated-17 with 1.8% relative (to 3629 line) chlorophyll content in mutant … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 24 Oct 2017 · 7,633 accessesView PDF Cite

Research ArticleOpen accessIn the abstractComparative Genomics of Domesticated and Wild Sunflower: Complete Chloroplast and Mitochondrial GenomesM. S. Makarenko, A. V. Usatov, N. V. Markin et al.The entire chloroplast and mitochondrial genomes of domesticated and wild type sunflower were sequenced. The comparative analysis of chloroplast genomes revealed 43 variant sites, including 21 polymorphic SSR loci and 22 SNPs. About 14 variant sites were found by collation of mitochondrial DNA (mtDNA), among them 4 SSRs, 8 SNPs and 2 deletions. About 9 SNPs were located in coding … …OnLine Journal of Biological Sciences, Vol. 16, Issue 1 · 29 Feb 2016 · 7,775 accessesView PDF Cite

Research ArticleOpen accessIn the abstractStructural Consequences of the Polymorphism Q223R in the Human Leptin Receptor: A Molecular Dynamics StudyJonathan P. Carrillo-Vázquez, Brenda Chimal-Vega, Beatriz Zamora-López et al.Leptin Receptor (LEPR) is a component of a signaling pathway related to appetite and energy expenditure. Single Nucleotide Polymorphisms (SNP) of Leptin receptor gene (lepr) have been proposed as possible modulator of adipose tissue and body weight. The main phenomenological consequence reported of these SNPs is the modulation of the LEP-LEPR interaction promoting the weight gain. Particularly, Q223R polymorphism has … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 3 · 23 Sep 2013 · 7,835 accessesView PDF Cite