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26 results for “Neurodegenerative Disease”
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Research ArticleOpen accessIn the abstractWhale Optimized Deep Generative Adversarial Network Based Alzheimer's Stages Detection Using 3D MRI Brain NeuroimagingR. Sampath, M. BaskarAlzheimer's Disease (AD), a common, chronic neurodegenerative condition, is characterized by the loss of neurons and synapses in the cerebral cortex and specific subcortical regions. According to claims from a recent study, AD has a 20% misdiagnosis rate. Therefore, it is essential to create a useful tool to recognize the stages of AD with a lower prediction error rate to … …Journal of Computer Science, Vol. 19, Issue 8 · 4 Aug 2023 · 5,549 accessesView PDFCite
Research ArticleOpen accessIn the abstractApoptosis in Yeast is Modulated by Clove Leaf Extract and Eugenol Potentially by Interfering Caspase YCA1Septyani Amini, Rika Indri Astuti, Irmanida BatubaraApoptosis is a process of cell death important for preventing the development of diseases such as cancer, neurodegenerative disorders, autoimmune, and cardiovascular disease. Apoptosis is reported to be potentially induced by antioxidant compounds, including phytoextract. Thus in this study, we determined the potential of apoptotic modulation in yeast cells by clove extract, which was rich in eugenol. Apoptotic in yeast … …OnLine Journal of Biological Sciences, Vol. 22, Issue 3 · 15 Sep 2022 · 5,504 accessesView PDFCite
Research ArticleOpen accessIn the abstractImproved Classification Model using CNN for Detection of Alzheimer’s DiseaseRagavamsi Davuluri, Ragupathy RengaswamyAlzheimer’s Disease (AD) is commonly called a neurodegenerative disorder and it is a common form of dementia. There is no permanent cure for this brain disease hence the early diagnosis of such disease using medical imaging system is highly significant. Machine learning models play a vital role in the detection of AD. Since most of the conventional machine learning models … …Journal of Computer Science, Vol. 18, Issue 5 · 30 May 2022 · 6,258 accessesView PDFCite
Case ReportOpen accessIn the abstractA Unique Presentation of Creutzfeldt-Jakob Disease in a Patient Consuming Deer Antler VelvetJoseph Wiedemer, Yanely Sanchez Ceja, An Cao, Ibrahim MustafaCreutzfeldt-Jakob Disease (CJD) is a rare rapidly progressive neurodegenerative prion disorder that is usually sporadic but may also be acquired from exposure to infected sources, classically via infections of bovine or human etiology. Cervid transmission of CJD is of particular concern in North America given the rapid spread of Chronic Wasting Disease (CWD)- the Cervid version of CJD. We present … …American Journal of Infectious Diseases, Vol. 17, Issue 1 · 18 Mar 2021 · 7,560 accessesView PDFCite
Literature ReviewOpen accessIn the abstractPotential Pathomechanism of Neuro-COVID-19Abir Fguirouche, Nissrine Louhab, Mohamed Chraa et al.Gathered data about SARS-CoV-2 have shown strong evidence in terms of neuroinvasive and neurotropic capacities of the virus to reach and cause eventual damage to the Central Nervous System. The spread of the virus may occur through direct and indirect ways, leading to anosmia and/or ageusia. These signs have been observed in many COVID-19 patients and are then included in … …OnLine Journal of Biological Sciences, Vol. 20, Issue 4 · 7 Dec 2020 · 6,544 accessesView PDFCite
Research ArticleOpen accessIn the abstractTailoring the Ruggiero-Klinghardt Protocol to Immunotherapy of AutismNicola Antonucci, Dietrich Klinghardt, Stefania Pacini, Marco RuggieroHere, we describe the adaptation to the field of autism of an original procedure denominated the "Ruggiero-Klinghardt Protocol" (RK Protocol), a procedure that represents a paradigm change with significant implications for chronic conditions where immunotherapy may prove effective; that is from silent infections to neurodegenerative diseases, autism and cancer. In the context of autism, the modified RK Protocol that we … …American Journal of Immunology, Vol. 14, Issue 1 · 25 Apr 2019 · 11,211 accessesView PDFCite
InvestigationOpen accessIn the abstractDevelopment of Genetic Constructions for Exctocytosis ControlIrina Nikolaevna Dominova, Vitaly Anvarovich Kasymov, Ekaterina Vladimirovna Silina et al.A fragment of the research project devoted to the development of genetic control of exocytosis is presented in the work, which can further ensure the success of targeted therapy of various diseases, including neurodegenerative ones. For the purpose of specific transfection of intracellular cascades in astrocytes in vivo, we have developed an experimental sample of the reagent kit. The latter … …OnLine Journal of Biological Sciences, Vol. 18, Issue 2 · 29 Jan 2018 · 7,313 accessesView PDFCite
Clinical ProcedureOpen accessIn the abstractThe Ruggiero-Klinghardt (RK) Protocol for the Diagnosis and Treatment of Chronic Conditions with Particular Focus on Lyme DiseaseDietrich Klinghardt, Marco RuggieroHere we describe the Ruggiero-Klinghardt (RK) Protocol that is based on integration of Autonomic Response Testing (ART) with diagnostic ultrasonography and on application of therapeutic ultrasounds; the latter are used as a provocation tool and as an instrument to optimize drug uptake and utilization in specific areas of the body. This protocol consists of a precise sequence of diagnostic and … …American Journal of Immunology, Vol. 13, Issue 2 · 8 Mar 2017 · 37,252 accessesView PDFCite
EditorialOpen accessIn the abstractBig Data and Parkinson’s Disease - from Understanding of Disease to Personalised MedicineYen F. Tai, Nicola PaveseThe advancement of information technology in recent years has generated a huge amount of datasets in all areas of scientific research. This has led to new opportunities to harness the 'Big Data' to improve our understanding of diseases - from investigating disease mechanisms to monitoring treatment responses. The Big Data approach is a data-driven and often hypothesis-free, way of studying … …Neuroscience International, Vol. 7, Issue 1 · 27 Jul 2016 · 7,761 accessesView PDFCite
Research ArticleOpen accessIn the abstractStem Cells in Traumatic Brain InjurySamuel Dobrowolski, Guilherme LepskiTraumatic Brain Injury (TBI) is a devastating clinical condition that often causes permanent incapacity, especially in the younger population. The clinical relevant of TBI justifies the scientific interest in the pathophysiology of TBI, as well as in protective effects and development of treatment options. Stem cells have the ability to induce neuroprotection and neural repair inflammatory suppression, causing tissue reconstruction … …Neuroscience International, Vol. 4, Issue 1 · 12 Apr 2013 · 7,568 accessesView PDFCite