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28 results for “Mutagen”
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Research ArticleOpen accessIn the keywordsChanges in Flower Development, Chlorophyll Mutation and Alteration in Plant Morphology of Curcuma alismatifolia by Gamma IrradiationThohirah Lee Abdullah, Johari Endan, B. Mohd NazirProblem statement: Curcuma alismatifolia Gagnep., commonly known as 'Thai tulip' or pathumma is a member of the family Zingiberaceae. This herbaceous perennial which can be grown from rhizomes have a great potential for use as a cut flower, flowering potted plant and as a garden plant for tropical landscaping. Unlike other bulbous floral crops, research on C. alismatifolia using gamma … …American Journal of Applied Sciences, Vol. 6, Issue 7 · 31 Jul 2009 · 8,437 accessesView PDFCite
Research ArticleOpen accessIn the keywordsStudy of pH and Cellular Response in Pulmonary Fibroblasts After Exposure to Market Street World Trade Center Particulate MatterMichelle Hernandez, Sung Choi, Ann Marie DiLorenzoChronic health conditions have been noted among first responders and residents exposed to the dust generated from the World Trade Center (WTC) collapse on September 11, 2001. This study sought to isolate a single factor thought to play a substantial role in the decreased lung function of World Trade Center (WTC) workers and victims. Human pulmonary fibroblasts were exposed to … …OnLine Journal of Biological Sciences, Vol. 12, Issue 4 · 8 Feb 2013 · 7,322 accessesView PDFCite
Research ArticleOpen accessIn the keywordsGenotoxicity through Exposure to Particulate Matter (PM10) at two Sites in the Valle de Aburrá, ColombiaVerónica Estrada-Vélez, Lucelly López-López, Lina María Martínez-Sánchez et al.To establish differences in the genotoxic effect of particulate matter (PM10) in exposed individuals at two sites in the Valle de Aburrá (VA). This was a descriptive cross-sectional study of 2 groups of individuals exposed to 67.7 and 45 µg/m3 of PM10 for a minimum of 8 hours/day. The frequency of Chromosomal Abnormalities (CAs) and the mitotic index were evaluated … …OnLine Journal of Biological Sciences, Vol. 19, Issue 1 · 19 Mar 2019 · 8,368 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIn silico Modeling of α1A-Adrenoceptor: Interaction of its Normal and Mutated Active Sites with Noradrenaline as well as its Agonist and AntagonistRamchandran Vijayan, Naidu Subbarao, Birendra Nath MallickNoradrenaline, like most other neurotransmitters, acts through various adrenoceptor subtypes. The structure and active site of adrenoceptors for the binding of noradrenaline were unknown, however, such information are crucial for understanding the molecular mechanism of action of neurotransmitters, including noradrenaline, in health and disease as well as for drug designing. In this in silico study, we modeled the α1A-adrenoceptor; a … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 7,140 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntioxidant and Antimutagenic Activities of Taif Grape (Vitis vinifera) CultivarsAbdelmegid Ibrahim Fahmi, Mohamed Ahmed Nagaty, Ahmed Mohamed El-ShehawiExtract of grape Vitis vinifera has been reported to exhibit antioxidant and antimutagenic activities and the phenolic compounds play a vital role in determining these activities. Therefore; the objective of the present study was to evaluate the antioxidant and anti-mutagenic activities as well as the phenolic composition of different grape cultivar extracts collected from Taif region. The grape cultivars namely; … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 2 · 20 Jun 2013 · 8,010 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessIn the abstractColor Doppler Evaluation of Isovolumetric Relaxation Time and of Signals Arising from Axons of the Median Nerve as a Means to Evaluate Mitochondrial Functionality in the Context of Immunotherapy of Cancer and Chronic Conditions Associated with Mitochondrial DysfunctionStefania Pacini, Marco RuggieroReactive Oxygen Species (ROS) arising from the disruption of mitochondrial respiration act as endogenous mutagens and tumor promoters. When production of ROS exceeds the capacity of DNA repair mechanisms, random mutations and aneuploidy ensue, thousands of genes become unbalanced and genetic/epigenetic chain reactions lead to progressive aneuploidy with only two outcomes: karyotypes so altered that are not viable or karyotypes … …American Journal of Immunology, Vol. 15, Issue 1 · 12 Oct 2019 · 9,690 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Cadmium on Worker Ovary Morphology of Bombus morio (Hymenoptera: Bombini)Fábio Camargo Abdalla, Marina Pedrosa, Caio Eduardo da Costa Domingues, Paulo José BalsamoBees are valuable bioindicators, providing information regarding environmental conditions through different kinds of analyses. Therefore, the effect of cadmium on the morphology of ovaries of Bombus morio workers was used to study a concentration considered environmentally safe (1 ppb) in Brazil. Workers of the same estimated age exposed for 48 h to 1 ppb cadmium showed extensive morphological changes in … …American Journal of Agricultural and Biological Sciences, Vol. 13, Issue 1 · 10 Apr 2018 · 9,140 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Investigation of Organelle Genomes of Extra Nuclear Sunflower Mutants with Variegated PhenotypeIrina Dremuk, Nikolay Kozel, Mariya Logacheva et al.The comparative analysis of complete chloroplast and mitochondrial DNA sequences of the original inbred line 3629 and three extra nuclear mutant lines variegated-1, variegated-15, variegated-17, obtained by the N-nitroso-N-methylurea induced mutagenesis, was done. The studied mutant lines were presented two different phenotypes with diverse chlorophyll content: Pale/green mutant line variegated-17 with 1.8% relative (to 3629 line) chlorophyll content in mutant … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 24 Oct 2017 · 7,633 accessesView PDFCite
EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDFCite