19 results for “Metabolic Disorders”

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Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDF Cite

Review ArticleOpen accessIn the abstractUnveiling the Impact of Endogenous Sialidases on Human Non-Infectious Disease PathogenesisRaisa Sergeevna Surkova, Anastasia Vladimirovna Poznyak, Dmitry Alexandrovich Kashirskikh et al.In our review, we have compiled existing information regarding the role of endogenous sialidases (neuraminidases) in the initiation and development of various non-infectious processes in humans. Precisely, pathologies of the cardiovascular system, tumor formations, neurological and metabolic disorders, and hereditary diseases. Sialidases appeared to be widely involved in a variety of human pathologies. An increase or decrease in the enzymatic … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 10 Feb 2024 · 4,546 accessesView PDF Cite

Review ArticleOpen accessIn the abstractCardiolipin in Pathology: Implications in AtherosclerosisAnastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Anton Yuvenalievich Postnov et al.Mitochondria are cell organelles whose main role is to generate the energy needed for cell biochemical reactions via oxidative phosphorylation. Cardiolipin is a phospholipid that is present in the inner mitochondrial membrane and other energy-transducing membranes. Mitochondrial structure largely depends on cardiolipin, as it is involved in the biogenesis of mitochondrial cristae, folds in the inner mitochondrial membrane designed to … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 23 Sep 2023 · 4,792 accessesView PDF Cite

Research ArticleOpen accessIn the abstractIn silico Assessment of the Arg85Trp Glucokinase Mutation EffectsFaiza Bouldjennet, Souhila Bouaziz-Terrachet, Malha Azzouz, Rachida RaacheMaturity Onset Diabetes of the Young (MODY) is a heterogeneous group of autosomal dominantly inherited, young-onset β-cell disorders that account for approximately 2% of non-insulin-dependent diabetics in Europe. MODY2 or GCK-MODY is caused by inactivating heterozygous mutations in the glucokinase. Linkage of MODY to the Arg85Trp GCK mutation, among Algerian diabetic patients has been established in our previous research. The … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 6,808 accessesView PDF Cite

Review ArticleOpen accessIn the abstractThe Duality of AIM2 Inflammasome: A Focus on its Role in Autoimmunity and Skin DiseasesMiriam CanaveseUnderstanding the inflammasome biology is one of the most exciting challenges in immuno-pharmacology. The role of the inflammasomes has been recognized in the host defense mechanism against invading pathogens and in the development of several conditions, such as cancer, auto-inflammatory, autoimmune, metabolic and neurodegenerative disorders. DNA recognition by the cells is a crucial immunological step leading to the initiation of … …American Journal of Pharmacology and Toxicology, Vol. 11, Issue 1 · 23 Apr 2016 · 7,369 accessesView PDF Cite

Research ArticleOpen accessIn the abstractInclusion of Molasses or Glucose Syrup in Starter Concentrate for Dairy Calves: Effects on Diarrheic CalvesMarcelo Cezar Soares, Carlos Eduardo Oltramari, Marília Ribeiro de Paula et al.Severity of metabolic acidosis and other clinical signs in diarrheic dairy calves fed a starter concentrate containing molasses or glucose syrup as a replacement for corn were evaluated. Thirty-two calves were blocked according to birth weight and were divided into four treatments according to starter concentrate composition: (1) Control, starter concentrate based on corn; (2) 5% of molasses as a … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 1 · 28 Mar 2016 · 7,254 accessesView PDF Cite

Research ArticleOpen accessIn the abstractCinnamon Extract Regulates Gene Expression of Lipid and Carbohydrate Metabolism in Streptozotocin Induced Diabetic Wistar RatsMohamed Mohamed Soliman, Mohamed Mohamed Ahmed, Samir Ahmed El-ShazlyCinnamon is a herbal medication plant used widely for many diseases in the Middle East and ancient countries. Cinnamon Extract (CE) contains many active substances that modulate insulin sensitivity and acts as anti-diabetic medication. Diabetes mellitus is a disease characterized by disturbance in carbohydrate and lipid metabolism. The aim of this study was to examine the effect of Cinnamon Extract … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 2 · 20 Jun 2013 · 8,043 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordFunctional Neuroimaging in Dementia and other Amnesic Disorders: A Radiological ReviewLeonardo Caixeta, Renata Teles Vieira, Sergio Machado et al.Problem statement: The structural and functional neuroimaging have much to contribute to the cognitive neuroscience. Approach: We describe a radiological review of the major dementia syndromes and Mild Cognitive Impairment (MCI), included Alzheimer's disease, Lewy body dementia, Vascular dementia, Front temporal Lobar degeneration, Dementia associated with parkinsonism and other amnesic syndromes. Results: The different syndromes and diseases presenting with dementia … …Neuroscience International, Vol. 2, Issue 1 · 23 Nov 2011 · 7,495 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordA Novel Rodent Model of Autism: Intraventricular Infusions of Propionic Acid Increase Locomotor Activity and Induce Neuroinflammation and Oxidative Stress in Discrete Regions of Adult Rat BrainDerrick F. MacFabe, Karina Rodríguez-Capote, Jennifer E. Hoffman et al.Innate neuroinflammatory changes, increased oxidative stress and disorders of glutathione metabolism may be involved in the pathophysiology of autism spectrum disorders (ASD). Propionic acid (PPA) is a dietary and gut bacterial short chain fatty acid which can produce brain and behavioral changes reminiscent of ASD following intraventricular infusion in rats. Adult Long-Evans rats were given intraventricular infusions of either PPA … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 12,613 accessesView PDF Cite