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91 articles for “Genetic Potential”
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Research ArticleOpen accessIn the abstractAnalysis of the Cytogenetic Status, Genome Instability, and Adaptive Potential of the Kazakh Tobet DogOksana Cherednichenko, Anastassiya Pilyugina, Dinara Azizbekova et al.In recent years, interest in indigenous dog breeds has increased. The Tobet is a unique breed of Kazakh livestock guardian dogs adapted to nomadic pastoralism that developed over thousands of years across Central Asia and Turkestan. Currently, the Tobet breed faces critical endangerment. Its conservation and sustainable breeding require thorough analysis of hereditary characteristics, genome stability, and adaptive potential. In … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 4 · 19 Feb 2026 · 1,891 accessesView PDFCite
Review ArticleOpen accessIn the abstractGoats’ Litter Size Concerning Bone Morphogenetic Protein 15 Gene VariationsTebogo Letsukulo Percy Thepa, Thobela Louis Tyasi, Jones Ng’ambiBone morphogenetic protein 15 (BMP15), a member of the transforming growth factor-β (TGF-β) superfamily, plays essential roles in follicular development and ovulation. Single nucleotide polymorphisms (SNPs) in the BMP15 gene have been associated with litter size in multiple livestock species, yet no comprehensive systematic review has synthesized findings across goat breeds. This systematic review aimed to evaluate the association between … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 4 · 18 Feb 2026 · 1,405 accessesView PDFCite
Literature ReviewOpen accessIn the abstractPotential Therapies for Mitochondrial Diseases Caused by mtDNA MutationsAnastasia V. Poznyak, Nikolay A. Orekhov, Dmitry Felixovich Beloyartsev et al.Mitochondrial diseases, caused by mutations in mitochondrial DNA (mtDNA), present significant genetic and clinical complexities that challenge accurate diagnosis and treatment. This review examines the critical molecular mechanisms underlying these disorders, particularly the role of heteroplasmy, where mixtures of mutated and normal mtDNA influence disease severity, and the nuclear-mitochondrial DNA interactions that compound diagnostic and therapeutic challenges. The threshold effect, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,735 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenetic Testing for Inherited Thrombophilia in Women with Recurrent Pregnancy Loss: Prevalence and Risk Assessment of Factor V Leiden, Prothrombin, and MTHFR MutationsLina M. Al Momani, Manal A. AbbasGenetic testing for inherited thrombophilia in women with recurrent pregnancy loss (RPL) may play an important role in detecting high-risk subjects. DNA was extracted from peripheral blood leukocytes. The high pure polymerase chain reaction template preparation kit and Reverse hybridization technique were used to detect the presence of factor V (G1691A, Leiden) (FVL), Factor II (prothrombin, G20210A), and 5,10-methylenetetrahydrofolate reductase … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 29 Nov 2025 · 2,559 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Analysis on Prediction of Chronic KidneyDisease by various Machine Learning ModelsNikhil Verma, Tripti Sharma, Bobbinpreet Kaur, Ayush DograChronic Kidney Disease (CKD) is a prevalent global healthconcern, which is affecting a number of people in the whole world. Earlydetection & precise checking of CKD are really important for essentialsupervision & intervention to prevent disease progression and associatedcomplications. Machine learning (ML) models have emerged as favourabletools for CKD detection due to their ability to analyse complex data patternsand provide … …Journal of Computer Science, Vol. 21, Issue 6 · 24 May 2025 · 5,939 accessesView PDFCite
Review ArticleOpen accessIn the abstractUnraveling the Mechanisms of Plant Structural Defenses against Insect PestsAroni Preya Biswas, Roksana Al Nafiu Insha, Md. Khairul Mazed et al.Plants employ a variety of physical, chemical, and genetic strategies to defend against herbivore attacks. These biochemical defense mechanisms are complex and dynamic, encompassing both direct and indirect responses. Defense-related chemicals, whether constitutive or induced by herbivore damage, significantly influence herbivore feeding behavior, growth, and survival. Plant defense systems impact herbivore nutrition, development, and survival, highlighting the importance of chemical … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 7 Jan 2025 · 5,793 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Novel Optimized Machine Learning Approach for Early Prediction of Heart Disease Using Bio-Inspired AlgorithmsIndira Priyadarsini, I.S. Siva Rao, P. Swetha et al.This study presents a novel approach for early prediction of heart disease using bio-inspired optimization algorithms to select and optimize features. The proposed approach utilizes a Genetic Algorithm (GA), Bat Algorithm (BA), Bee Algorithm (BA), and Ant Colony Optimization (ACO) to optimize a set of four features for improved prediction accuracy. The optimization process aims to identify the most relevant … …Journal of Computer Science, Vol. 21, Issue 1 · 4 Dec 2024 · 5,227 accessesView PDFCite
Literature ReviewOpen accessIn the abstractSystematic Review of Single Nucleotide Polymorphisms of Cattle Beta-Lactoglobulin Gene and their Association with Milk Production TraitsThlarihani Cynthia Makamu, Thobela Louis TyasiThe application of molecular genetics technology to pinpoint certain DNA markers associated with commercially significant features is highly anticipated since it has the potential to enhance the effectiveness of breeding programs by selecting young animals early for use as future breeding stock. One of the main genes expressed in bovine milk is the Beta-Lactoglobulin Gene (βLG), and its polymorphism can … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 2 · 4 Mar 2024 · 5,811 accessesView PDFCite
Research ArticleOpen accessIn the abstractFirst Morphoanatomical and Cytogenetic Characterization of Picria fel-terrae Lour.: A Local Accession from Dairi Regency, IndonesiaElimasni, Deny Supriharti, HaryatiPoguntano (Picria fel-terrae Lour.) plant has been widely recognized for its medicinal properties due to its bioactive compounds. However, fundamental biological studies, particularly on its phenological and cytogenetic characteristics, remain limited. This study aimed to characterize the vegetative morphology and karyotypic features of P. fel-terrae from Dairi Regency, North Sumatra, to provide a comprehensive cytogenetic database for future study and … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 17 Jul 2026 · 745 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssociation Between Cancer Screening Results Using Single Nucleotide Polymorphism and Cancer Incidence Rate in Korean WomenKyung Bae Lee, Jae Kyung KimIn this study, we investigated the usefulness of Single Nucleotide Polymorphism (SNP) testing in assessing cancer susceptibility in women by evaluating correlations between SNP testing results and cancer incidence rates. SNP testing was conducted on blood samples of women who underwent health examinations commissioned by medical institutions in the Republic of Korea in 2017 using real-time polymerase chain reaction with … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 25 Sep 2023 · 4,956 accessesView PDFCite