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180 articles for “human change”
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Research ArticleOpen accessIn the abstractEvaluating Web Usability from the User's PerspectiveHema Banati, Punam Bedi, P.S. GroverThe presence of multiple websites offering similar services has changed the user outlook. The user now prefers to visit those sites, which are easy to use. Many different methods have been proposed to measure usability of a website. The quantitative methods focus on the performance measurement of the website whereas the qualitative methods estimate the user's opinion of a website. … …Journal of Computer Science, Vol. 2, Issue 4 · 30 Apr 2006 · 8,430 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn vitro Effects of Beet Root Juice on Stimulated and Unstimulated Peripheral Blood Mononuclear CellsChristiana Winkler, Barbara Wirleitner, Katharina Schroecksnadel et al.Intake of fruits and vegetables rich in antioxidants is suggested to reduce the incidence of cancer and coronary heart disease in humans. Exceptional antioxidant activity of beet root extracts has been reported. Likewise in animal models, e.g., extracts of red beetroot Beta vulgaris var. rubra revealed significant tumor inhibitory effects. Red beetroot concentrate is universally permitted as a food ingredient. … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 4 · 31 Dec 2005 · 9,528 accessesView PDFCite
Research ArticleOpen accessIn the abstractImatinib Mesylate Inhibits Glucose Uptake in Gastrointestinal Stromal Tumor Cells by Downregulation of the Glucose Transporters Recruitment to the Plasma MembraneHans Prenen, Cristiana Stefan, Bart Landuyt et al.Imatinib mesylate, the inhibitor of the KIT protein tyrosine kinase that is constitutively activated in Gastrointestinal Stromal Tumors (GISTs), has been established as the first highly effective drug in the treatment of patients with advanced GISTs. Recent studies suggest that changes in the glucose metabolism could be an additional mechanism of the anti-proliferative action of imatinib. The aim of this … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 7,248 accessesView PDFCite
Research ArticleOpen accessIn the abstractExtracts of Pumpkin (Cucurbita pepo L.) Seeds Suppress Stimulated Peripheral Blood Mononuclear Cells in vitroChristiana Winkler, Barbara Wirleitner, Katharaina Schroecksnadel et al.In the traditional medicine in North America and Mexico, pumpkin seeds have been used as an anthelmintic agent and for supportive treatment in functional disorders of the bladder. Also anti-inflammatory and cardioprotective activity of pumpkin seeds is discussed. Three different extracts of pumpkin seeds were prepared and effects were investigated in unstimulated human peripheral blood mononuclear cells and in cells … …American Journal of Immunology, Vol. 1, Issue 1 · 31 Mar 2005 · 10,717 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordMan Invades Nature: Tracing the Dynamics and Trends of Anthropogenic Stressors Within a Coastal Wetland EnvironmentEmmanuel Yeboah Okyere, Kofi Adu-Boahen, Bismark MensahCoastal areas contain some of the most valuable resources on earth that are constantly under threat due to human development. Notable among these resources are wetlands, a delicate but beneficial asset to coastal dwellers. This study studied the growth of Winneba City into the Muni Lagoon catchment as well as its associated effects on the Ramsar Site. The study used … …Journal of Social Sciences, Vol. 19, Issue 1 · 16 Jun 2023 · 6,055 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordThe Impact of Air Pollution on Human Health: Focusing on the Rudnyi Altay Industrial AreaVitaliy G. Salnikov, Marat A. KaratayevProblem statement: Air pollution in Kazakhstan is significant environmental problem. The air pollution level of cities and industrial centers remains rather high. The highest level of air pollution is registered in Ridder, Ust-Kamenogorsk, Almaty, Zyryanovsk, Aktau, Atyrau, Shymkent, Taraz, Petropavlovsk and Temirtau. The enterprises of the Rudnyi Altay, Pavlodar Oblast and enterprises of oil and gas complex in West-Kazakhstan, Atyrau … …American Journal of Environmental Sciences, Vol. 7, Issue 3 · 21 Jul 2011 · 10,451 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordCytotoxicity and Apoptosis Prevailed by Tricyclohexyltin(IV) Dithiocarbamate Compounds Against Human Lung Carcinoma Cell Line (A549)Normah Awang, Nurul Amalina Abd Aziz, Nur Fatini Nordin, Nurul Farahana KamaludinIn Malaysia, lung cancer is a highly common kind of cancer and the leading cause of cancer-related deaths. This study examined the cytotoxicity of two new tricyclohexyltin(IV) dithiocarbamate compounds compounds, which are tricyclohexyltin(IV) N-methyl-N-benzyldithiocarbamate (C1) and tricyclohexyltin(IV) N-ethyl-N-benzyldithiocarbamate (C2), on lung carcinoma cell lines (A549) of humans. The cytotoxicity was assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay. Cell death mode … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 13 Jun 2024 · 4,627 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordHepato and Nephrotoxicity Caused by Sub-Chronic Exposure to Relevant Concentrations of Human Exposure to Glyphosate-Based Herbicide: An Experimental Study in RatsFernanda de Maria Serra, Letícia Rocha Magalhães, Beatriz Bertholace Magalhães Silva et al.Glyphosate's remarkable effectiveness in weed control has made it among the foremost widely employed herbicides globally. Several Glyphosate-Based Herbicides (GBHs) contain 1-4 dioxane, a compound known to induce cancer in animals and potentially contribute to liver and kidney damage in humans. The objective was to assess the liver and kidney toxicity resulting from sub-chronic exposure to GBH in rats. Eighty … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 26 Dec 2023 · 5,198 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordPassage Effect on Aging of Human Umbilical Cord Derived Mesenchymal Stem CellDian Mediana, Isabella Kurnia Liem, Jeanne Adiwinata Pawitan, Noviyanti GoeiTo be used in regenerative medicine, cells should be checked for various conditions, including cell aging. This study aimed to learn senescent profile and its relation to cell viability, proliferation and cell size in various passages, which were done in α-MEM-10% PRP medium, until senescence-associated β-galactosidase (SA-β-Gal) positive cells were found. Stem cells were isolated from umbilical cord tissue by … …OnLine Journal of Biological Sciences, Vol. 15, Issue 3 · 31 Jul 2015 · 8,041 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordPreparedness in Implementing Action Plan for Reducing GHGs: The Case of Central JavaAgung SugiriThe Regional Action Plan for Reducing Greenhouse Gas Emissions (RAD-GRK) of Central Java Province 2020 was completed in 2012. This paper assesses the preparedness of the Central Java Provincial Government (CJPG) to implement the plan and identifies measures needed to ensure successful implementation based on the stakeholders' perceptions. In-depth interviews with key CJPG officials and a workshop with the extended … …American Journal of Environmental Sciences, Vol. 11, Issue 1 · 2 Apr 2015 · 8,102 accessesView PDFCite