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132 articles for “toxic effect”
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Research ArticleOpen accessIn the abstractBioaccumulation of Arsenic by FungiAdemola O. AdeyemiProblem statement: Arsenic is a known toxic element and its presence and toxicity in nature is a worldwide environmental problem. The use of microorganisms in bioremediation is a potential method to reduce as concentration in contaminated areas. Approach: In order to explore the possible bioremediation of this element, three filamentous fungi-Aspergillus niger, Serpula himantioides and Trametes versicolor were investigated for … …American Journal of Environmental Sciences, Vol. 5, Issue 3 · 30 Jun 2009 · 7,890 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of D- and L-Glucose and Mannitol on Retinal Capillary Cells: Inhibition by Nanomolar AminoguanidineYongxin Yu, Wei Li, Barbara Wojciechowski et al.Hyperglycemia may contribute directly to pericyte loss and capillary leakage in early diabetic retinopathy. To elucidate relative contributions of glycation, glycoxidation, sugar autoxidation, osmotic stress and metabolic effects in glucose-mediated capillary damage, we tested the effects of D-glucose, L-glucose, mannitol and the potentially protective effects of aminoguanidine on cultured bovine retinal capillary pericytes and endothelial cells. Media (containing 5 mM … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 4 · 31 Dec 2007 · 7,749 accessesView PDFCite
Research ArticleOpen accessIn the abstractSorbitol-Induced Diabetic-Like Retinal Lesions in Rats: Microscopic StudyGaber A. RamadanThe present study investigated the sorbitol toxicity on the retinas of normal albino rats and founded by the light microscope that intra-peritoneal injection of Sorbitol (10-mg/kg-body weight per day) for 24 weeks produced similar diabetic like retinal lesions in these rats. The retinopathic effects of sorbitol injection affect retinal microvessels, pigment epithelium, neural retina and glial cells. Cytoplasmic vacuolation of … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 2 · 30 Jun 2007 · 7,630 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of Genotoxic Activity of Para-nitrophenol in Higher Plant Using Arbitrarily Primed- polymerase Chain Reaction (AP-PCR)Mohamed R. EnanParanitrophenol is a common toxic environmental pollutant; the aim of this study was to evaluate the potential of the DNA fingerprinting by AP-PCR assay to detect the DNA damage in the common bean (Phaseolus vulgaris) exposed to different concentrations of paranitrophenol (4.0-720 nM). The changes occurring in the fingerprint patterns were likely to be the result of paranitrophenol-induced DNA damage. … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 2 · 30 Jun 2007 · 7,064 accessesView PDFCite
Research ArticleOpen accessIn the abstractControl of Anthracnose Caused by Colletotrichum musae on Curcuma alismatifolia Gagnep. Using Antagonistic Bacillus spp.Supuk Mahadtanapuk, Mondhon Sanguansermsri, Robert W. Cutler et al.Over 400 bacterial strains, isolated from leaf surfaces of Curcuma alismatifolia Gagnep. and hot springs in the Chiang Mai province of northern Thailand, were screened in vitro for antagonistic activity against Colletotrichum musae, an anthracnose fungus. Three isolates provided greater than 75% growth inhibition of the fungus in vitro and were identified as Bacillus licheniformis, B. amyloliquefaciens and B. subtilis. … …American Journal of Agricultural and Biological Sciences, Vol. 2, Issue 2 · 30 Jun 2007 · 9,005 accessesView PDFCite
Research ArticleOpen accessIn the abstractCharacteristics of Nitrogen Removal from Old Landfill Leachate by Sequencing Batch Biofilm ReactorLong Tengrui, Anas F. Al-Harbawi, Lin Ming Bo et al.Municipal landfill leachate is a high strength wastewater characterized by high concentrations of organics and ammonia and potentially containing toxic materials. The paper reports the results of a laboratory scale investigation aimed at evaluating the effectiveness of mature municipal landfill leachate treatment by a biological stage (used SBBR as a biological treatment) to study the nitrogen removal capabilities for treatment … …American Journal of Applied Sciences, Vol. 4, Issue 4 · 30 Apr 2007 · 8,039 accessesView PDFCite
Research ArticleOpen accessIn the abstractPharmacological Screening of Arceuthobium oxycedri (Dwarf Mistletoe) of Juniper Forest of PakistanMudassir Asrar Zaidi, Ahsan Huda, Sidney A. CrowThe local population of Balochistan, Pakistan considers the Juniperus excelsa an important medicinal plant. The species is facing a grave threat by a parasitic and epiphytic angiosperm, dwarf mistletoe, Arceuthobium oxycedri (DC) M. Bieb (Viscaceae). The methanolic extract of A. oxycedri was studied for its chemical composition and biologically active compounds for the first time. The extract was assayed for … …OnLine Journal of Biological Sciences, Vol. 6, Issue 2 · 31 Dec 2006 · 7,001 accessesView PDFCite
Research ArticleOpen accessIn the abstractRetinoids Chemosensitize Ovarian Cancer Cell Lines to Cisplatin Independent of Nuclear Receptors and p53Suresh Guruswamy, Doris M. BenbrookTreatment of ovarian cancer with cisplatin-based chemotherapy is highly toxic and is often followed by cancer recurrence. Repeated treatments with cisplatin frequently result in the development of resistance to this drug. Drugs with low toxicity that could enhance the tumor cell killing effects of cisplatin could potentially reduce the toxicity and enhance the efficacy of cisplatin. The mechanism of cell … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 6,958 accessesView PDFCite
Research ArticleOpen accessIn the abstractRapamycin Inhibits Cystogenesis by Cystic Epithelial Cells Derived from Human Autosomal Dominant Polycystic KidneysGerard Elberg, Teresa V. Lewis, Lijuan Chen, Martin A. TurmanAutosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic disorders and carries a high health burden since it progresses to renal failure in half of the afflicted individuals by the 6th decade of life. Currently, there is no effective treatment to slow the progression of ADPKD. Rapamycin, a drug most commonly used as an immunosuppressive agent … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 7,101 accessesView PDFCite
Case ReportOpen accessAll words, across the recordEffects on the Immune System of a Three-Month Consumption of an Extremely Diverse Probiotic Yogurt: Decrease of Serum Alpha-N-Acetylgalactosaminidase Activity, Detoxification and Gut Microbiota NormalizationJerry Blythe, Marco RuggieroIn this study, we describe the changes associated with the consumption of an extremely biodiverse probiotic yogurt in a 55-year-old female from South Vietnam. In August 2019, the subject voluntarily embarked on a three-month nutritional experience and decided to share her results with the goal of advancing scientific knowledge in the field of nutritional health. Consumption of this biodiverse probiotic … …American Journal of Immunology, Vol. 16, Issue 1 · 22 Oct 2020 · 9,697 accessesView PDFCite