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Research ArticleOpen accessIn the abstractγ-Aninobutyric acid (GABA) suppresses antigen-specific immune responses in ovalbumin γ(OVA)-immunized BALB/c miceTohru Sakai, Hiroko Okada, Mitsuo Kise et al.γ-Aminobutruic acid (GABA) is known to be a ubiquitous inhibitory neurotransmitter in the central nervous system. Furthermore, recent studies have shown that GABA modulates cardiovascular and respiratory functions. In this study, we examined the effect of GABA on antigen (Ag)-specific immune responses and elucidated the mechanisms underlying those effects in ovalbumin (OVA)-immunized BALB/c mice. OVA-specific proliferative responses were decreased in … …American Journal of Immunology, Vol. 1, Issue 3 · 30 Sep 2005 · 6,501 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordStudy on the Enhancement of Hypoglycemic and Antioxidant Activities of Compound Herbal Tea through Solid-State FermentationQing Liu, Xiaowen Que, Yueping Yang et al.This study utilized Aspergillus niger KY2295 for the Solid-State Fermentation (SSF) of a compound tea made from Cinnamomum cassia bark, Glycyrrhiza glabra, Morus abla L. leaf, and Crataegus oxyacantha L. to enhance its hypoglycemic effects. The fermentation process was optimized using single-factor experiments and a Central Composite Design (CCD), with α-amylase and α-glucosidase inhibitory activities as evaluation indices. Following fermentation, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 1 · 20 May 2025 · 5,473 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordPreparing and Antimicrobial Activity of Hydrogel with Biosynthesized Silver Nanoparticles Using Carex Meyeriana KunthQihui Shen, Henan Zhu, Hongli Zhou et al.In this study, a simple and environmentally stable method was developed to synthesize silver Nanoparticles (AgNPs). In addition, carex meyeriana kunth was used as a reducing and stabilizing agent with good bacterial inhibitory effects against Escherichia coli (E. coli) and Bacillus subtilis at very low doses. AgNPs were added to the Polyvinyl Alcohol (PVA) solution as an antibacterial agent and … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 2 · 4 May 2023 · 5,724 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordHydroxyl Radical-Scavenging Activity-Guided Extraction of Peptides from Oviductus ranaeJieyang Shen, Yihui Liu, Jiahao Xu et al.Oviductus Ranae (OR) is a traditional Chinese medicinal material that is listed in Chinese Pharmacopeia with proteins the most abundant ingredients. In present work, pepsin/trypsin-based stepwise hydrolysis was applied to extract Antioxidant Peptides from OR (APOR) using hydroxyl radical-scavenging capacity as evaluation index. After single-factor experiment, response surface method coupled with Box-Behnken design were used for optimizing process parameters and … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 4 · 18 Oct 2021 · 6,609 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordOptimization of Cellulase-Assisted Extraction of Total Flavonoids from Corn Bract and Evaluation of Antioxidant and Antibacterial AactivitiesYang Zhang, Jing Lu, Leijie Ben et al.Corn bract is a corn-based agricultural waste material that distributed worldwide. In present work, response surface methodology was applied to optimize the cellulase-assisted extraction of Total Flavonoids from Corn Bract (TFCB), the in vitro antioxidant and antibacterial as well as the in vivo antioxidant activities of TFCB were investigated. Results showed that the optimal conditions for TFCB extraction were as … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 2 · 18 May 2019 · 8,501 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordMicrowave Assisted Regioselective Synthesis and Biological Evaluation of Pyrano[2,3-c]Pyridine Derivatives Utilizing DMAP as a CatalystAsmaa M. FahimRegioselective facile production of pyrano[2,3-c]pyridine through multicomponent reaction of aromatic aldehydes, ethyl cyano acetate or malononitrile and C-H activated compound of 3-hydroxy picolinic acid in the occurrence of smaller amount of DMAP catalyst utilizing microwave apparatus, which is green and simple environmentally with high yield, recyclability catalyst. Totally the products were partitioned for antimicrobiogical action; it was detected that were … …OnLine Journal of Biological Sciences, Vol. 17, Issue 4 · 14 Dec 2017 · 8,019 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordRETRACTED: Evaluation of the Cytotoxic Activity of Aqueous Extract of Schinus terebinthifolius RaddiA. Arnóbio, O. N. Terra Jr., P. R.G. Lemos et al.Phytotherapy consists in all pharmaceutical preparation using certain part of plants as a feedstock with known pharmacological effects for medicinal purposes. In order to a better understanding of the biological effects associated with herbal medicines, many scientific studies have been conducted and developed in recent years. SchinusterebinthifoliusRaddi (Aroeira) is native from Peru and is also found in Europe, Asia and … …American Journal of Infectious Diseases, Vol. 8, Issue 4 · 8 Feb 2013 · 7,611 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordInhibitory Effect of Ginger Extract on Candida albicansZahra Atai, Manijeh Atapour, Maryam MohseniProblem statement:The fungal infections could be life-threatening in immunocompromised patients. Candida albicans is the most frequent fungi in the oral cavity. Approach: The first step for treatment could be done using topical antifungal agents. Nystatine is a choice for mentioned usage but there are some problems in its using including: unfavorite taste, frequency of usage, etc. Finding better replacements is … …American Journal of Applied Sciences, Vol. 6, Issue 6 · 30 Jun 2009 · 9,968 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordBacteriological Examination of Computer Keyboards and Mouse Devices and Their Susceptibility Patterns to DisinfectantsOnochie Charles Chimezie, Anyim Chukwudi, Alo Moses Nnaemeka et al.Computers are ubiquitous and have been shown to be contaminated with potentially pathogenic bacteria in some communities. There is no economical way to test all the keyboards and mouse out there, but there are common-sense ways to prevent bacterial contamination or eliminate it if it exists. In this study, swabs specimens were collected from surfaces of 250 computer keyboards and … …Current Research in Microbiology, Vol. 4, Issue 1 · 19 Jan 2013 · 13,509 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordZerumbone: A Natural Compound with Anti-Cholinesterase ActivityAhmad Bustamam, Siddig Ibrahim, Adel S. Al-Zubairi et al.Herbal dugs could be a new source for inhibitors of acetyl cholinesterase (anti-AChE), the key enzyme in the breakdown of acetylcholine and a new talented approach for the cure of elderly neurologically associated disorders such as Alzheimer’s disease (AD). Zerumbone (ZER) is sesquiterpene from the edible plant, Zingiber zerumbet which is known to possess tremendous biological activities. In this study, … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 3 · 30 Sep 2008 · 9,638 accessesView PDFCite