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20 results for “Xiao Zhang”

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Research ArticleOpen accessIn the author namesEffect of Metformin Treatment on Inflammatory Factors and Gut Microbial Diversity in Patients with Type II Diabetes MellitusLei Tong, Jingjing Zhang, Li Xiao Yue et al.With the persistent rise in the prevalence of Type 2 Diabetes Mellitus (T2DM), traditional treatment evaluations have primarily focused on glycemic control, often overlooking the multidimensional effects of medications. As a first-line therapeutic agent, the anti-inflammatory effects and gut microbiota regulation mechanisms of metformin remain incompletely elucidated. This prospective cohort study established a metformin treatment group and a T2DM control … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 20 Jul 2026 · 785 accessesView PDFCite
Research ArticleOpen accessIn the author namesParameter-Expanded Data Augmentation for Analyzing Nominal Data With Missing Values Using Multinomial Probit ModelsSuwash Silwal, Xiao ZhangNominal data occur in many scientific fields, such as health-related studies, transportation, and econometrics. Due to the ubiquitousness of missing data, it is inevitable to analyze nominal data with missing values. As is well known, statistical methods for analyzing nominal variables are quite limited. The Multinomial Probit (MNP) model has been an essential tool for analyzing nominal categorical data, but … …Journal of Mathematics and Statistics, Vol. 22, Issue 1 · 23 May 2026 · 1,814 accessesView PDFCite
Research ArticleOpen accessIn the author namesOptimization of Preparation Procedures of Phlorizin-Zn (Ⅱ) Complex and Its Antioxidant Activity Study in vitroYuqing Zhang, Yaping Li, Guorui Yang et al.Flavonoid metal complexes possess more effective antioxidant properties than flavonoids. However, the preparation of the phlorizin-Zn (Ⅱ) complex and its antioxidant activity has not been reported. In this research, the preparation procedures of the phlorizin-Zn (Ⅱ) complex were enhanced using by single factor test and Response Surface Methodology (RSM). The optimal preparation procedures of the phlorizin-Zn (II) complex were as … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 3 Apr 2024 · 4,761 accessesView PDFCite
Research ArticleOpen accessIn the author namesThe Effect of Trilobatin on Bovine Serum Albumin: Interaction Mechanism and Molecular DockingYuhan Zhai, Yuqing Zhang, Yaping Li et al.Understanding the transport and distribution of small molecules in vivo is aided by studying their interactions with proteins. As a natural sweetener, trilobatin possesses several biological activities. However, uncertainty surrounds the trilobatin and Bovine Serum Albumin (BSA) interaction mechanism. In this study, the binding types, number of binding sites and binding constants of trilobatin interaction with BSA were studied by … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 1 · 29 Mar 2024 · 4,846 accessesView PDFCite
Research ArticleOpen accessIn the author namesTrilobatin Possesses Protective Potentials on H2O2-Induced HepG2 Cells by Suppressing Oxidative Stress: Involvement of Nrf2/Keap1 Signal PathwayYuhan Zhai, Yuqing Zhang, Yaping Li et al.Trilobatin, a natural dihydrochalcone compound, possesses various biological activities. However, few investigations have been carried out on the mechanisms of trilobatin against oxidative stress. To comprehend the effects and mechanism of trilobatin on oxidative stress after hepatic injury, H2O2-induced HepG2 cells were used in this research. The results indicated that trilobatin enhanced the viability and improved the apoptosis morphology of … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 22 Dec 2023 · 5,089 accessesView PDFCite
Research ArticleOpen accessIn the author namesAntioxidant Activity of Trilobatin and Its Inhibitory Effects on Oxidative Damage of Biological MacromoleculesYuhan Zhai, Yuqing Zhang, Yaping Li et al.Excessive levels of free radicals in the body cause oxidative damage to macromolecules by injuring DNA, proteins, and lipids, which leads to structural and functional defects and ultimately results in a number of illnesses. The antioxidation of trilobatin and its inhibitory activity of trilobatin on oxidative damage of biological macromolecules have not been thoroughly investigated. In this research, the effects … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 28 Oct 2023 · 5,470 accessesView PDFCite
Research ArticleOpen accessIn the author namesBayesian Analysis of Longitudinal Ordinal Data Using Non-Identifiable Multivariate Probit ModelsXiao ZhangMultivariate probit models have been explored foranalyzing longitudinal ordinal data. However, the inherent identification issuein multivariate probit models requires the covariance matrix of the underlyinglatent multivariate normal variables to be a correlation matrix and thushinders the development of efficient Bayesian sampling methods. It is knownthat non-identifiable models may produce Markov Chain Monte Carlo (MCMC)samplers with better convergence and mixing than … …Journal of Mathematics and Statistics, Vol. 18, Issue 1 · 14 Nov 2022 · 6,047 accessesView PDFCite
Research ArticleOpen accessIn the author namesPreparation of Rosemary Collagen Chitosan Blend Membrane Using Response Surface Methodology (RSM)Ming He, Yuhan Zhai, Yuqing Zhang et al.The present research provided a formula for the optimization of rosemary/collagen/chitosan blend membrane. Rosemary Extract (RE) was used as additive and membrane was prepared using tensile strength, elongation at break and elongation length as the indexes. The results of single factor experiment showed that the addition ratio of collagen to chitosan, additive content, glycerol content and drying temperature all affected … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 4 · 22 Nov 2021 · 6,244 accessesView PDFCite
Research ArticleOpen accessIn the author namesCharacterization of Crude Polyphenol Oxidase Activity in Buckwheat SproutsYuedong Song, Yangfang Zhang, Yilin Wang et al.Buckwheat sprouts can not only effectively reduce the trypsin inhibitor in buckwheat grain, but also improve the content of bioactive ingredients such as flavonoids and other effective components. However, Polyphenol Oxidase (PPO) in buckwheat sprouts causes browning of food, which limits the application of buckwheat sprouts in food. In addressing this problem, studying the characteristics of PPO in buckwheat sprouts … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 2 · 25 Jun 2021 · 6,487 accessesView PDFCite