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Research ArticleOpen accessIn the abstractProgressive LDL Reduction to Very Low Levels Improves Dimeric Nitric Oxide Synthase, Nitric Oxide Bioavailability and Reduces Peroxynitrite in Endothelial Cells during HyperglycemiaR. Preston Mason, Hazem Dawoud, Samuel C.R. Sherratt et al.Circulating levels of glucose and LDL influence Endothelial Cell (EC) function in a highly interactive manner as evidenced by nitric oxide production and coupling of endothelial Nitric Oxide Synthase (eNOS) dimer. Here, we report on the status of eNOS function in Human Umbilical Vein Endothelial Cells (HUVECs) cultured under normo- and hyperglycemic (250 mg/dL) condition followed by exposure to increasing … …American Journal of Pharmacology and Toxicology, Vol. 14, Issue 1 · 2 May 2019 · 8,363 accessesView PDFCite