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34 results for “ulcer”
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InvestigationOpen accessEvery word in the titleRegularities of the Oxidative Stress Processes in Case of Bleedings from Acute and Chronic Ulcers of the Stomach and DuodenumEkaterina Vladimirovna Silina, Mukimdjon Ahmadzhonovich Sobirovz, Sergey Brankovich Bolevich, Victor Aleksandrovich StupinThe main aim of the study was to determine ways of improving the results of treating patients with ulcer bleeding of various nature and severity. It was provided by the system study of free radical processes and evaluation of the effectiveness of timely antioxidant therapy. Material and methods. The study included 153 patients aged 18-94 years with acute and chronic … …OnLine Journal of Biological Sciences, Vol. 18, Issue 2 · 4 May 2018 · 7,416 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Evaluation of Proton Pump Inhibitor Bioactive Fraction DLBS2411 from Cinnamomum burmannii (Nees & T. Nees) in Animal Model of Gastric Ulceration HealingFlorensia Nailufar, Raymond Rubianto TjandrawinataDLBS2411 is a bioactive fraction from Cinnamomum burmannii that is believed to possess anti-ulceration activity. In this study acetic acid was administered to induce gastric ulcer. Rats were divided into six groups: Healthy animals, untreated animals (acetic acid-induced), treatment group of BAF DLBS2411 25 mg kg-1 Body Weight (BW), BAF DLBS2411 50 mg kg-1 BW and positive control group of … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 4 · 28 Feb 2018 · 9,939 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePressure Ulcer Prevention: Optimizing a Temporally Redistributing Support InterfaceJoshua M. Peterson, Colleen P. Healey, G. Jacobus Visser et al.One of the most common complications from long-term wheelchair use or bed rest is pressure ulcers. Pressure ulcers have significant morbidity and are associated with high mortality. Prolonged sitting can cause high pressures in the skin and subcutaneous tissue which can lead to local ischemia and breakdown of skin. Rapid relief of pressure prevents ulcer formation. One prevention strategy is … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 22 Dec 2016 · 7,897 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePOST KALA-AZAR DERMAL LEISHMANIASIS WITH ULCERATION ON FOOT: AN ATYPICAL CASE PRESENTATION SUCCESSFULLY TREATED WITH MILTEFOSINEVidyanand Rabi Das, Dharmendra Singh, Krishna Murti et al.Visceral Leishmaniasis (VL) or Kala-Azar (KA) is highly endemic in the Indian subcontinent particularly in Bihar. Post Kala-azar Dermal Leishmaniasis (PKDL) is a known reservoir for leishmania parasites for transmission of VL. The kala-azar elimination program was launched by the government of three countries of the Indian subcontinent in the year 2005, which aims to eliminate kala-azar by 2015 and … …American Journal of Infectious Diseases, Vol. 10, Issue 2 · 2 Apr 2014 · 7,583 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSitagliptin Impairs Healing of Experimentally Induced Gastric Ulcers Via inhibition of iNOS and COX-2 ExpressionAmina Unis, Eman AbdelzaherGastric ulcer healing is a complex process that is regulated by several promoting factors including COX-2 and iNOS. Diabetes mellitus is usually associated with delayed gastric ulcer healing. Hence, the current study was designed to investigate the effect of sitagliptin (dipeptidyl peptidase-4 inhibitor) on gastric ulcer healing and expression of iNOS and COX-2 in rat stomach.The study was conducted on … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 3 · 4 Sep 2013 · 7,436 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnti-Microbial, Anti-Oxidant and Anti-Ulcerogenic Effects of Shilajit on Gastric Ulcer in RatsMohamed-I. Kotb El-Sayed, Hatem-K. Amin, Ali-G. Al-KafProblem statement: To evaluate the effects and mechanisms of action involved in anti-ulcer, antioxidant and antimicrobial activities of different native shilajit samples. Approach: Shilajit samples were collected in the mountain region of Yemen (Al-Jouf and Rayma), Russia (Tien-Shan) and India (Kumoan). Stomach ulcers were induced in rats by oro-gastric ingestion of ethanol/HCl. Pre-treatment with ranitidine (100 mg kg-1, p.o.) and … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 1 · 10 Mar 2012 · 8,996 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnti-Ulcer (Ulcer-Preventive) Activity of Ficus arnottiana Miq. (Moraceae) Leaf Methanolic ExtractMarslin Gregory, K. P. Vithalrao, G. Franklin, V. KalaichelavanProblem statement: In spite of being one of the well-known medicinal plants used in Indian traditional medicine to treat several ailments, studies pertaining to the pharmacological properties of Ficus arnottiana are very scarce. We studied the anti-ulcer activity and acute toxicity of Ficus arnottiana leaf methanolic extract for the first time. Approach: Freshly collected F. arnottiana leaves were dried, powdered … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 9,329 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCytoprotective Effect of UlGen, a Polyherbal Formulation against Physical and Chemical Factor Induced Gastric Ulcers in Wister Albino RatsT. S. Muralidhar, Anna Balaji, Chinmay Bandopadhyay, S. L. ShanthaProblem statement: UlGen, a Polyherbal formulation, was investigated for its possible Ulcero-protective activity in ulcerogen and Cold-restraint stress induced Wister rats (Rattus rattus). Oral administration of UlGen, at a dose of 800 mg kg-1 significantly protected the onset of cold-resistance stress induced ulcerations. Approach: It significantly inhibited gastric ulceration induced by alcohol and aspirin. Control group: Alcohol 80% induced ulcer … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 8,180 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleGastroprotective Effects of Melastoma malabathricum Aqueous Leaf Extract against Ethanol-Induced Gastric Ulcer Iin RatsFouad Hussain, Mahmood Ameen Abdulla, Suzita Mohd Noor et al.The gastro-protective effects of the aqueous leaf extract of Melastoma malabathricum was investigated against ethanol-induced gastric mucosal injuries in rats. There were four groups of adult sprague dawley rats, consisting of six rats per group. Macroscopically, oral administration of absolute ethanol to rats that had been pre-treated with only distilled water significantly produced extensive lesions of the gastric mucosa. Oral … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 4 · 31 Dec 2008 · 7,774 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleWound Healing Process of Uncomplicated “Rusterholz” Ulcer, Following Treatment by Wooden Block and Hoofgel® in Bovine Hoof: Histopathological AspectsH. Azarabad, I. Nowrouzian, E. Soleymani et al.A broad and very detailed histopathological knowledge on cutaneous wound healing particularly in human skin is available, but few studies have documented this event in bovine claw sole ulcers. It seems the mechanism of wound healing might be basically the same followed by second intention healing which is finished in a period of time by formation of granulation tissue in … …American Journal of Animal and Veterinary Sciences, Vol. 1, Issue 2 · 31 Dec 2006 · 7,847 accessesView PDFCite