16 articles for “treatment of malaria”

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Research ArticleOpen accessIn the keywordsStimulatory Effects of Dihydroartemisinin on the Leucocyte Population of Wistar Albino RatsU. A. Utoh-Nedosa, P. A. Akah, C. O. Okoli et al.Problem statement: Five dosages of Dihydroartemisinin (DHA) which included 1 mg kg-1; a repeated dose of 1; 2; 60 and 80 mg kg-1 were administered orally to albino rats for 5 days. The results of the study showed that dihydroartemisinin treatment significantly elevated the total white cell count (p<0.01); the percentage neutrophil count (p<0.01) and the percentage lymphocyte count (p<0.05). … …American Journal of Infectious Diseases, Vol. 7, Issue 3 · 17 Nov 2011 · 7,350 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsRespiratory Tract-Widening Effects of Dihydroartemisinin in Wistar Albino RatsUtoh-Nedosa Uchechukwu, Njoku Goddy, S. Nedosa Kenechi et al.Problem statement: Artemisinin-based anti-malarials are currently widely used in Asia and Africa. Not much is known about the systemic effect of dihydroartemisinin. This study therefore examine the effect of dihydroartemisinin on the lungs of Wistar albino rats. Approach: Five dosages of Dihydroartemisinin (DHA) were administered by oral intubation for 5 days to 5 test and 4 control Wistar albino rats. … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 2 · 17 Aug 2011 · 7,515 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsMalaria and Climate Change: Discussion on Economic ImpactsMd. Shahin Mia, Rawshan Ara Begum, Ah-Choy Er et al.Problem statement: Climate change is a global environmental change that is adversely affecting human health by causing various health impacts in countries throughout the world. Climate is the most influential driving force of vector-borne diseases such as malaria. Changes in climate factors substantially affect reproduction, development, distribution and seasonal transmissions of malaria. Climate change increases the outbreak of malaria which … …American Journal of Environmental Sciences, Vol. 7, Issue 1 · 28 Feb 2011 · 6,584 accessesView PDF Cite

Case ReportOpen accessIn the abstractA Case Report of Severe Malaria Due to Plasmodium falciparum Malaria Complicated by Symmetrical Peripheral Gangrene (SPG) at the Matlaboul Fawzaini National Hospital Center, Touba, SenegalJules Yindoni Zande, Ndeye Fatou Ngom et al.Malaria remains a major public health problem worldwide, particularly in Africa. Symmetrical Peripheral Gangrene (SPG) is a distal ischemic lesion affecting at least two extremities in the absence of proximal arterial obstruction and vasculitis. It is a rare and severe clinical entity. Its association with malaria is rare, with approximately 27 cases reported worldwide, mostly in Asia. A 15-year-old male … …American Journal of Infectious Diseases, Vol. 21, Issue 1 · 22 Jan 2026 · 2,806 accessesView PDF Cite

Research ArticleOpen accessIn the abstractOptimal Control of a Malaria Transmission Model with Saturated IncidencePerpetual Appiah, Henry Amankwah, Francis BenyahWe present a vector-host deterministic model for the transmission and control of malaria, using prevention and treatment as controls. A novel addition to our model is a new prevention function that highlights the role of prevention in reducing vector populations; an essential arsenal in the fight against malaria. Another innovation is the use of a novel treatment function, which reflects … …Journal of Mathematics and Statistics, Vol. 20, Issue 1 · 29 Feb 2024 · 5,894 accessesView PDF Cite

Research ArticleOpen accessIn the abstractWhy Continue Studying HRP2 and HRP3 in Malaria?María Luz Gunturiz, Pablo Enrique Chaparro, Gabriel Carrasquilla, Mónica Marcela JiménezThe main malaria control strategy is rapid and accurate diagnosis followed by effective treatment. The quality of the diagnosis is relevant, since an erroneous diagnosis can generate an increase in morbidity and mortality significantly. The World Health Organization (WHO) has recommended that all patients with suspected malaria be diagnosed by microscopy or a Rapid Diagnostic Test (RDT) before treatment. Microscopy … …American Journal of Infectious Diseases, Vol. 16, Issue 3 · 24 Aug 2020 · 6,897 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEffect of GA3 and Shading on the Growth and Content of Artemisinin Compound in Leaf of Artemisia (Artemisia annua L.) Grown on the Medium Land of Karanganyar, IndonesiaYuni Kusumodewi, Usman Siswanto, Samanhudi, Ahmad YunusMalaria is still becomes a concern for the government of Indonesia, since this disease has affected many people. Artemisia annua L. is an aromatic plant that destroys malarial parasites, lowers fever and of which the secondary metabolite is artemisinin. Enhanced production of the artemisinin content in the whole plant is desirable. This experiment was conducted in Karanganyar, Indonesia 900m asl. … …American Journal of Applied Sciences, Vol. 14, Issue 10 · 1 Nov 2017 · 8,007 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEffects of Artemisinin-Based Combination Therapies on Lipids and Hepatorenal Circulating Indices in Guinea PigsAbaram Chesa Mankwe, Jonah Sydney Aprioku, Atuboyedia Wolfe ObianimeArtemisinin-based Combination Therapies (ACTs) are employed as first-line agents in malaria chemotherapy. In many malaria endemic areas, ACTs are frequently abused partly due to resistance, poor drug control and inadequate health facilities. This study investigated the effects of prolong administration of Artesunate-Sulfadoxine-Pyrimethamine (ATS-SP), Artesunate-Amodiaquine (ATS-Amod) and Artemether-Lumefantrine (ATM-Lum) on plasma levels of biochemical parameters (AST, ALT, ALP, urea and creatinine) … …American Journal of Pharmacology and Toxicology, Vol. 11, Issue 2 · 3 Apr 2017 · 7,282 accessesView PDF Cite

Research ArticleOpen accessIn the abstractIN VIVO ANTIPLASMODIAL ACTIVITY AND ACUTE TOXICITY OF STANDARDIZED EXTRACT OF EURYCOMA LONGIFOLIA JACK. ROOT TRADITIONALLY USED TO TREAT MALARIAEti Nurwening Sholikhah, Mahardika Agus Wijayanti, MustofaA series of studies has been conducted to prove the Eurycoma longifolia Jack. root as an antimalarial. However, the in vivo antiplasmodial activity of E. longifolia Jack. root standardized extract and its lethal dose 50% (LD50) values is unknown. In vivo antiplasmodial activity was conducted on Plasmodium berghei infected Swiss mice as malaria model with 4-day suppression methods. Sixty mice … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 27 Dec 2013 · 7,732 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAn Overview of Malaria ControlEmmanuel Chanda, Mulakwa Kamuliwo, Richard W. Steketee et al.Malaria remains a serious global public health problem and a leading cause of morbidity and mortality in sub Saharan Africa. In Zambia the disease is endemic with stable transmission, accounting for 40% of all out-patient attendances and is responsible for 20% deaths among children under five. Scaling up of scientifically proven high impact preventive, curative and supportive interventions and deploying … …Current Research in Medicine, Vol. 4, Issue 1 · 29 Apr 2013 · 7,960 accessesView PDF Cite