76 articles for “toxic effects”

Research ArticleOpen accessPhrase in the titleEvaluation of the Toxic Effects of Dihydroartemisinin on the Vital Organs of Wistar Albino RatsA. U. Utoh-Nedosa, P. A. Akah, T. C. Okoye, C. O. OkoliProblem statement: The current surge in the use of Artemisinin based Combination Therapy (ACT) in the treatment of falciparium resistant malaria in the tropics and the potentials of Dihydroartemisinin (DHA), a member of the artemisinin family, to produce toxic effect in the vital organs (such as the liver, heart, lungs, intestine, spleen kidney and blood cells) necessitated this research. Approach: … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 9,181 accessesView PDF Cite

Research ArticleOpen accessPhrase in the titleAssessment of the Toxic Effects of Chitosan-Coated Magnetite Nanoparticles on Drosophila melanogasterDoris Vela, Jonathan Rondal, Sofía Cárdenas et al.Nanoparticles are a cause for concern because of their potential toxic effects on human health and the environment. The aim of this study was to assess the toxic effect of chitosan-coated magnetite nanoparticles (11.00±4.7 nm) on Drosophila melanogaster through the observation of hemolymph composition, DNA damage, larval survival and lifespan of flies. Chitosan-coated magnetite nanoparticles were synthesized by co-precipitation method. … …American Journal of Applied Sciences, Vol. 17, Issue 1 · 25 Sep 2020 · 7,882 accessesView PDF Cite

Research ArticleOpen accessPhrase in the titleAssessing the Toxic Effects of Topik80ec on Rabbit Testicular Morphometry and HistologySamia Rebahi, Alouani Abdelouahab, Meguini Mohamed Nadir et al.This study aimed to investigate the toxic impact of Topik80ec on rabbit testes through morphometric and histological analyses. Twenty-four adult male domestic rabbits (Oryctolagus cuniculus) were used, where three experimental groups, G1, G2, and G3, were assigned and provided escalating dosages of Topik80 EC for a duration of four weeks, while one group served as the control group and received … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 14 Sep 2024 · 5,015 accessesView PDF Cite

Research ArticleOpen accessPhrase in the titleABSENCE OF VISIBLE TOXIC EFFECTS ACCOMPANYING THE SHORT-TERM ADMINISTRATION OF AN AQUEOUS EXTRACT OF ALLIUM SATIVA LINN. IN MALE SPRAGUE-DAWLEY RATSJ. Asiedu-Gyekye Isaac, Awortwe Charles, A. Antwi DanielAllium sativum is cultivated in the northern part of Ghana and has gained widespread use as chemoprotective, in curing hypertension, impotence and erectile dysfunction. The multipurpose use together with its aphrodisiac activity has resulted in the widespread use of this plant medicine both in meals and as herbal medications. Safety assessment of this plant however is rare. The present study … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 30 Jan 2014 · 7,577 accessesView PDF Cite

Research ArticleOpen accessPhrase in the titleDose-Dependent Neurotoxic Effects of Monosodium Glutamate and its Potential Genetic Transmission in MiceYanan Zou, Qiong Liang, Lu Liu et al.This study aimed to preliminarily investigated the neurotoxic effects of monosodium glutamate on mice and their pups, and the potential possibility of a genetic mechanism influencing the pups. In this study, mice were given different doses of Monosodium Glutamate (MSG) at doses of 2.0 or 4.0 g/kg body weight for 10 continuous days, and its impacts on both the mice … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 14 Nov 2025 · 3,031 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleTherapeutic Effects of Turnera diffusa Extract Against Amitriptyline-Induced Toxic Hepatic InflammationAhmed F. Hasan, Thulfiqar F. Mutar, Ehab Moustafa Tousson, Shatha Ghazi FelembanTricyclic Antidepressants Including Amitriptyline (AMI), stop the reabsorption of norepinephrine and serotonin, so the levels of transmitters is elevated in the brain to lead to several side effects. Therefore, current study aimed to assay liver dysfunction that attended by AMI administration and monitoring of damiana Turnera diffuse role as adjuvant therapy to improving amitriptyline hepatic effects in male rats. 60 … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 29 Jun 2021 · 8,286 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleThe Health and Toxic Adverse Effects of Fusarium Fungal Mycotoxin, Fumonisins, on Human PopulationW. M. Wan Norhasima, A. S. Abdulamir, F. Abu Bakar et al.Problem statements: Fumonisin was a mycotoxin produced mainly by fungi belonging to the genus Fusarium in various foods and feeds. They occurred worldwide and were found predominantly in corn and in corn-based animal feeds and also can be found in other crops. Contamination of food and feed with fumonisins has been implicated in and associated with a number of diseases … …American Journal of Infectious Diseases, Vol. 5, Issue 4 · 31 Dec 2009 · 9,030 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleIndications of Potential Toxic/Mutagenic Effects of World Trade Center Dust on Human Lung Cell CulturesConstantino G. Lambroussis, Barbara D. Soares, Sergio Perez et al.Problem statement: Respiratory complications have been linked with exposure to dust particulates after the tragedy of September 11th, 2001 at the World Trade Center (WTC) site. Approach: The purpose of these experiments was to investigate the extent of cellular damage resulting from WTC dust exposure. Results: This research project was conducted with human lung fibroblast cells exposed to WTC dust. … …OnLine Journal of Biological Sciences, Vol. 9, Issue 3 · 30 Sep 2009 · 7,394 accessesView PDF Cite

Research ArticleOpen accessIn the abstractToxicity of Dinoflagellate (Gonyaulax verior) from Makassar Strait Waters on Medaka Fish (Oryzias javanicus) Embryo DevelopmentNita Rukminasari, Khusnul Yaqin, Jamaluddin Fitrah AlamThis study investigates the toxic effects of the dinoflagellate Gonyaulax verior on the embryonic development of medaka fish (Oryzias javanicus) sourced from four distinct aquatic environments in the Makassar Strait. Given the increasing presence of harmful algal blooms in marine ecosystems, understanding the impact of toxic dinoflagellates is crucial for assessing risks to fish populations. Embryos were exposed to varying … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 20 Nov 2025 · 2,123 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAntiproliferative Potential of Pomegranate Peel Extract in MDA-MB Breast Cancer Cell LinesManal Asif Hamdulay, Fatema Yusuf Singaporewala, Grisilda Vidya Bernhardt et al.Nutraceuticals have gained recognition as adjuvant therapies in cancer treatment due to their non-toxic and protective properties. Among various natural products, pomegranate peel with high antioxidant capacity and rich polyphenol content suggest potential anticancer properties. Previous studies have shown promising anticancer effects of other parts of the pomegranate. The purpose of this research is to compare the effectiveness of Pomegranate … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 1 · 13 May 2025 · 5,582 accessesView PDF Cite