5 results for “super-oxide”

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Research ArticleOpen accessIn the keywordsDihydrobiopterin (BH2): Key Determinant in Influencing Arginine Mediated Endothelial Tolerance and DysfunctionSrinidi Mohan, Harsh Patel, Jorge Bolinaga et al.The redox-sensitive tetrahydrobiopterin (BH4) is an essential cofactor that is required by endothelial Nitric Oxide Synthase (eNOS) for L-arginine (ARG) mediated Nitric Oxide (NO) generation. Oxidation of BH4 causes cofactor insufficiency and uncoupling of eNOS, resulting in product switching from NO to O2⋅– production. Here we tested the hypothesis that eNOS uncoupling is not simply a consequence of BH4 insufficiency, … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 8,348 accessesView PDF Cite

Research ArticleOpen accessIn the abstractTHE IMPACT OF ANTIOXIDANTS ON INFLAMMATION AND OXIDATIVE STRESS MARKERS IN OSTEOARTHRITIS RAT MODEL: SCANNING ELECTRON MICROSCOPE INSIGHTSEl Hassan Heidar, FareedF Al Faya, Waleed N. Hassan et al.Osteoarthritis (OA) is characterized by degradation of matrix and destruction of articular cartilage. Articular chondrocytes are solely responsible for the production and maintenance of the extracellular matrix. Therefore, chondrocyte disruption is implicated in cartilage degeneration. Numerous studies have shown that antioxidant treatments are promising therapeutics in cases of OA. This study was designedto examine whether vitamin E protects rat articular … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 19 May 2014 · 7,616 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEVALUATION OF THE ANTI-ARTHRITIC EFFECT OF STERCULIA TRAGACANTHA (LINDL.) LEAF EXTRACT IN RATSUdegbunam Rita Ijeoma, Nwaehujor Chinaka Onyebuchi, Udegbunam Sunday OsitadimmaSterculia tragacantha leaves for years have been used by traditional healers in eastern Nigeria in the treatment of arthritis, edema, gout, whitlow and cold. The aim of this study was to evaluate the folkloric claims of Sterculia tragacantha leaf extract in relieving arthritic conditions. The effects of Sterculia Tragacantha methanol leaf Extract (STEX) on formaldehyde and adjuvant-induced arthritis were studied … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 11 Mar 2014 · 7,588 accessesView PDF Cite

Research ArticleOpen accessIn the abstractProtective Effect of Enicostemma littorale Blume on Rat Model of Diabetic NeuropathyNiraj Mukundray Bhatt, Suparna Barua, Sarita GuptaProblem statement: Poor glycemic control and oxidative stress is implicated as a common pathway in the development of diabetic neuropathy. Approach: In the present study, we investigated the protective effects of Enicostemma littorale Blume (EL) (2.5 g kg-1), a hypoglycemic and antioxidant herbal medicine in alloxan-induced diabetic neuropathy in male Charles foster rats. Results: Tail flick latency in hot immersion … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,838 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordSynthesis and Charaterization of Magnesium Zinc Ferrites as Electromagnetic SourceNoorhana Yahya, Ami Salwani Mohamad Nor Aripin, Azizuddin A. Aziz et al.Fabrication of Mg1-XZnXFe2O4 (where x = 0.2, 0.3, 0.4 and 0.5) samples using a conventional technique is reported. Oxides of magnesium, zinc and iron with purity of about 99.99% were mixed with distilled water in a milling machine for 12 hours. They were then filtered and presintered at 1250°C and sintered at 1350°C for 10 h in air. The phase … …American Journal of Engineering and Applied Sciences, Vol. 1, Issue 1 · 31 Mar 2008 · 8,998 accessesView PDF Cite