Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

109 articles for “specific target”
Set a search alert
Research ArticleOpen accessIn the keywordsMolecular Medicine-Prospects and ChallengesC. N. Ramchand, R. Sripathy, N. Somashekara et al.Drug discovery and development is a process that rationally leads to instigation of compound or formulation for the treatment of particular disease/diseased condition by acting on its specific target (s). Most of the drugs identified by conventional drug discovery process were as a result of unsystematic, random and serendipitous approach. Enhancement of knowledge in the field of biotechnology, molecular biology … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 23 Feb 2012 · 7,473 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Transformer Based Model to Detect Environmental Related Distress on Online Social MediaUtkarsh Sharma, Prateek Pandey, Shishir KumarOnline social media has been recently employed as the source of data for the detection of traffic-related activities and to control the flow of traffic in smart cities all over the world. Till now an ample amount of research work has been done in identification of traffic-related incidents with the help of online social media platforms (mostly Twitter). Along with … …Journal of Computer Science, Vol. 22, Issue 11 · 9 Oct 2026 · 462 accessesView PDFCite
Research ArticleOpen accessIn the abstractMorphological Diversity of Isolated Mycobacterial Cultures in the Republic of Kazakhstan: Implications for Diagnostics and TreatmentAssiya Borsynbayeva, Kairat Turgenbayev, Gulzhauhar Sarsenova et al.The study of mycobacterial morphology in the Republic of Kazakhstan is relevant due to the increasing burden of tuberculosis and other mycobacterial diseases. The aim of this study was to comprehensively describe the morphological characteristics of different mycobacterial species identified in Kazakhstan, which will help to improve diagnostic methods and develop new approaches to treatment. Comparative and cross-cultural analyses were … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 1 Dec 2025 · 2,203 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Drug-Target Interaction Prediction Based on Supervised Probabilistic ClassificationManmohan Singh, Susheel Kumar Tiwari, G. Swapna et al.Bayesian ranking-based drug-target relationship prediction has achieved good results, but it ignores the relationship between drugs of the same target. A new method is proposed for drug-target relationship prediction based on groups by Appling Bayesian. According to the reality that drugs interacting with a specific target have similarities, a grouping strategy was introduced to make these similar drugs interact. A … …Journal of Computer Science, Vol. 19, Issue 10 · 1 Sep 2023 · 5,454 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Toolkit Approach for Carbon Capture and Storage in Offshore Depleted Gas FieldRaj Deo Tewari, Tan Chee Phuat, Mohd Faizal SedaralitFossil fuels are considered a dependable, cost-effective, and efficient energy source and their utilization has resulted in tremendous growth for humanity. However, it has its downside also. Experts are of the view that present energy systems are unsustainable due to their detrimental impacts on the environment. Oil and gas producers are charged that their infrastructure, utilization of materials and technologies … …American Journal of Environmental Sciences, Vol. 19, Issue 1 · 17 May 2023 · 6,196 accessesView PDFCite
Review ArticleOpen accessIn the abstractChallenges in Healthcare Waste Management of the UN 2030 Agenda in the COVID-19 EraGabriella Marfe, Stefania Perna, Arturo HermannToday, the COVID-19 pandemic has caused a remarkable and sudden increase in global demand for Personal Protective Equipment (PPE), such as masks, gloves, gowns. The growing biomedical and municipal streams of potentially infectious waste is a new challenge for every country since an inadequate waste management might have serious public health consequences and significant impact on the environment. In this … …American Journal of Environmental Sciences, Vol. 18, Issue 1 · 7 Mar 2022 · 7,576 accessesView PDFCite
Research ArticleOpen accessIn the abstractA GUI-Enabled, Automated LSTM-Based Inverse Kinematics Pipeline for 6-DOF Robotic Arms Using MATLAB and CoppeliaSimWaleed Abdulrahman Saleh Al-Akwa, Mohammed Abdulwahab Ahmed DabaExisting deep learning-based inverse kinematics (IK) solutions often target specific robotic arms and require significant modifications when applied to different configurations. To support early-phase design and testing of 6-degree-of-freedom (6-DOF) robotic arms, this study presents a fast and adaptable IK solution through a user-friendly interface. Unlike traditional numerical methods that are computationally intensive, sensitive to initial conditions, and may not … …Journal of Mechatronics and Robotics, Vol. 9, Issue 1 · 26 May 2025 · 8,252 accessesView PDFCite
Literature ReviewOpen accessIn the abstractUnraveling Sterile Inflammation in Atherosclerosis: Mechanisms, Implications and Therapeutic StrategiesAnastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Anton Yuvenalievich Postnov et al.Atherosclerosis, a leading factor in the development of cardiovascular diseases, is a complex and multifaceted condition with inflammation emerging as a pivotal determinant of its pathogenesis. This review comprehensively investigates the role of sterile inflammation in atherosclerosis and deliberates on potential therapeutic interventions targeting this underlying mechanism. Despite advancements in the understanding of atherosclerosis, diagnosing, preventing, and choosing effective treatment … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 4 Mar 2025 · 3,965 accessesView PDFCite
Literature ReviewOpen accessIn the abstractThe Relationship between Obesity, Insulin Resistance and Hypertension: A ReviewMasah Mardini, Lana Dardari, Maher Taha et al.Obesity is considered a global epidemic with detrimental health effects. It is linked to the development of conditions such as diabetes mellitus, hypertension, hyperlipidemia, coronary heart disease, atherosclerotic cerebrovascular disease, and higher mortality rates, among other conditions. This review elucidates the pathophysiology linking obesity, insulin resistance, type 2 diabetes, and hypertension and includes clinical trials that demonstrate these relationships. Electronic … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 16 Aug 2024 · 5,076 accessesView PDFCite
Research ArticleOpen accessIn the abstractUltrastructural Morphology of the Muscle System Organization in the Trematode Typhlocoelium cucumerinumIrina Yurievna Chidunchi, Ainagul Balgauovna Kaliyeva, Natalya Petrovna Korogod et al.Trematodes, also known as flatworms, are a diverse group of parasitic organisms that live in a variety of ecosystems, from freshwater to marine habitats. Their complex life cycle often involves intermediate and definitive hosts and multiple developmental stages. Trematodes have unique morphological features that allow them to adapt, move and parasitize within host tissues and organs. The parasitic lifestyle of … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 1 Jun 2024 · 5,112 accessesView PDFCite