2 results for “retinal pigment epithelium”

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Research ArticleOpen accessIn the keywordsAttenuated Superoxide Dismutase Induction in Retinal Cells in Response to Intermittent High Versus Continuous High GlucoseMichael A. Ihnat, Ronald C. Kaltreider, Jessica E. Thorpe et al.High glucose, particularly in oscillating conditions, produces an increase in oxidative stress and has been shown to result in an increase in diabetic complications, retinopathy in particular. The hypothesis of this work was that chronic exposure to intermittent high glucose results in an attenuated induction of an antioxidant response as compared to continuous high glucose exposure in isolated retinal cells … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 1 · 31 Mar 2007 · 7,453 accessesView PDF Cite

Research ArticleOpen accessIn the abstractSorbitol-Induced Diabetic-Like Retinal Lesions in Rats: Microscopic StudyGaber A. RamadanThe present study investigated the sorbitol toxicity on the retinas of normal albino rats and founded by the light microscope that intra-peritoneal injection of Sorbitol (10-mg/kg-body weight per day) for 24 weeks produced similar diabetic like retinal lesions in these rats. The retinopathic effects of sorbitol injection affect retinal microvessels, pigment epithelium, neural retina and glial cells. Cytoplasmic vacuolation of … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 2 · 30 Jun 2007 · 7,630 accessesView PDF Cite