82 results for “resistant strain”

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Research ArticleOpen accessPhrase in the titleDetermination of Optimum Values of Descriptors to Set Filters for Synthetic Tri-Pyrrole Derivatives (Prodiginines) Against Multi Drug Resistant Strain of Plasmodium FalciparumVijay H. Masand, Devidas T. Mahajan, Eslam Pourbasheer et al.In the present study, we have carried out extensive non-linear Quantitative-Structure Activity Relationship (QSAR) analysis to correlate in vitro anti-malarial activity against multi drug resistant strain of Plasmodium falciparum. Forty-three synthetic prodiginines with different structural features were used for their potential antimalarial activity. Linear, bilinear, biexponential and parabolic equations were developed. These equations were compared to determine the optimum values … …Current Research in Drug Discovery, Vol. 1, Issue 2 · 26 Jan 2015 · 14,141 accessesView PDF Cite

Research ArticleOpen accessPhrase in the titlePrevalence of Drug-Resistant Strains of Streptococcus Pneumoniae in AbakalikiIroha Ifeanyichukwu Romanus, Okafor Florence Njideka, Nwakaeze Emmanuel Amobi et al.Streptococcus pneumoniae is a major cause of illness such as pneumonia, meningitis, bacteremia and otitis media in children and the elderly. The emergence of drug-resistant strains threatens to complicate the management of these diseases. We conducted a hospital-based surveillance for drug-resistant Strep. Pneumoniae in outpatients with pneumococcal infection in Abakaliki Ebonyi State Nigeria. Between 2003-2005 from January through December, a … …American Journal of Infectious Diseases, Vol. 8, Issue 3 · 26 Nov 2012 · 7,677 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleCharacterization of a Multi-Metal Resistant Bacillus cereus Strain TWSL_5 and it’s Bioremediation Potential for Cr, Pb, Zn and FeWeerasingha Mudiyanselage Nilmini Hasintha Kumari, Naduviladath Vishvanath Chandrasekharan, Champika Dilrukshi WijayarathnaAn effluent sample collected from a textile dyeing factory was screened to isolate metal resistant endogenous bacteria using standard microbiology techniques. A bacterium with the highest metal resistance was characterized by 16S rRNA gene sequencing and the bacterial genome was screened for any possible metal resistant genes using the Polymerase Chain Reaction (PCR). The bioremoval ability of the isolate was … …American Journal of Environmental Sciences, Vol. 17, Issue 3 · 15 Jul 2021 · 6,443 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleEvaluation of Different Drugs in Down-Regulation of Efflux Pump Genes expression in Methicillin-Resistant Staphylococcus aureus StrainsManu Chaudhary, Santosh Kumar Patnaik, Anurag PayasiAntimicrobial resistance caused by efflux systems is not widely studied in Staphylococcus aureus. In the present study, prevalence of NorA and NorB efflux pumps was studied in thirteen Methicillin-Resistant Staphylococcus aureus (MRSA) strains using a pair of primers with Polymerase Chain Reaction (PCR). Antibiotic susceptibility study in NorA and NorB efflux positive isolates was carried out according to the Clinical … …American Journal of Infectious Diseases, Vol. 10, Issue 4 · 7 Jan 2015 · 7,451 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleCirculation of Multidrug-Resistant (MDR) and Extensively Drug-Resistant (XDR) Mycobacterium Tuberculosis Strains in MexicoCarlos A. Vazquez-Chacon, Armando Martinez-Guarneros, Susana Balandrano Campos et al.Emergence of Extensively Drug-Resistant (XDR) Tuberculosis (TB) is an important public health problem worldwide. In Mexico, the extent of circulation of XDR-TB strains is unknown. Here, the drug-resistance patterns of TB isolates collected in Mexico between 2006 and 2008 were analyzed. Among 137 TB isolates, (58%) were classified as MDR exclusively, (33%) were Pre-XDR and (9%) were assigned as XDR. … …American Journal of Infectious Diseases, Vol. 10, Issue 4 · 7 Jan 2015 · 7,422 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleDifferential Activities of Glutathione S-Transferase Isoenzymes in Strains of Fasciola Hepatica Susceptible and Resistant to TriclabendazoleV. Fernández, P. Ortiz, M.V. Solana, H. SolanaFasciolosis, a parasitic zoonosis of intrahepatic location, is caused by the trematode Fasciola hepatica. Its control is mainly based on the use of the anthelminthic Triclabendazole (TCBZ). The indiscriminate use of this drug has favored the development of anthelmintic resistance. The Glutation S-Transferases (GSTs) are multifunctional enzymes involved in the detoxification of xenobiotics and endogenous compounds using conjugation with endogenous … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 10 Dec 2014 · 7,574 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsUse of Enterobacterial Repetitive Intergenic Consensus PCR in Detecting Target(s) of Hapalindole-T, From a Cyanobacterium, in Escherichia Coli: In Silico ValidationManoj K. Tripathi, Maheep Kumar, Vinay K. Singh et al.Problem statement: Identification of newer biomolecule as well as targets are a rising concern because of increasing drug resistance in bacteria. We have isolated a broad spectrum antibiotic biomolecule Hapalindole-T from a cyanobacterium, Fisherella sp. growing on local Azadirachta indica tree bark. A model bacterium E. coli was screened spontaneously for Hap-T resistance. These resistant strains of E. coli were … …Current Research in Bioinformatics, Vol. 1, Issue 1 · 3 Mar 2012 · 13,777 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsGlass Strength for Impact and Blast LoadingMatthias Förch, Frank WellershoffGlass strength is highly influenced by strain rate. This material behaviour is well known in structural glass design and implemented in various standards. The strength of architectural glass is determined by component tests with a defined strain rate of 2 N/(mm2s), providing favourable terms for testing. As typical effects of actions on facades result in lower or higher strain rates, … …International Journal of Structural Glass and Advanced Materials Research, Vol. 5, Issue 1 · 7 May 2021 · 8,115 accessesView PDF Cite

Research ArticleOpen accessIn the abstractDistribution and Risk Factors of Carbapenem-Resistant Enterobacterales in General Hospitals in South KoreaMijin Kang, Bokyeung Jung, Jaekyung KimThe emergence of Carbapenem-Resistant Enterobacterales (CRE) presents a significant global health challenge due to its high resistance to broad-spectrum β-lactam antibiotics. CRE infections are increasingly common in hospital settings and are associated with high mortality rates. In South Korea, the increase in CRE infections necessitates a detailed investigation into their distribution and risk factors to inform effective management and prevention … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 1 · 27 Mar 2025 · 5,759 accessesView PDF Cite

Research ArticleOpen accessIn the abstractBioremediation Potential of Heavy Metal-Resistant Bacteria in Koto Panjang Reservoir, Riau, IndonesiaIrda Sayuti, Darmadi, Adrian Hartanto et al.Koto Panjang Reservoir serves as a vital water resource supporting the social well-being of the local community in the Riau Province. The flow of the Kampar River, acting as the riverine zone and water inlet to the reservoir, provides environmental support for the construction of hydroelectric power plants (PLTA) and the aquaculture practice of Floating Net Cages (FNC). Over the … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 10 Feb 2025 · 4,534 accessesView PDF Cite