5 results for “renal metabolism”

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Research ArticleOpen accessIn the keywordsKidney Function Indices in Mice after Long Intake of Agaricus brasiliensis Mycelia (=Agaricus blazei, Agaricus subrufescens) Produced by Solid State CultivationDalla Santa Herta Stutz, Rubel Rosália, Vitola Francisco Menino Destéfanis et al.Problem statement: Agaricus brasiliensis (=Agaricus blazei, Agaricus subrufescens) or Sun mushroom has widespread use for potential health benefits such anti-tumor and immunomodulatory effects. Studies detected that others edible mushrooms affected renal metabolism and despite the widespread use of A. brasiliensis there are no studies that address biological effects on the renal function indices after their oral administration. Therefore, this study … …OnLine Journal of Biological Sciences, Vol. 9, Issue 1 · 31 Mar 2009 · 8,149 accessesView PDF Cite

EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDF Cite

EditorialOpen accessIn the abstractImpact of Quantitative Pharmacology on Drug DevelopmentAna Ruiz-Garcia, Kourosh ParivarThesuccess of drug development rests over two well defined pillars, a goodunderstanding of the drug’s clinical pharmacology and the appropriate targetpopulation for whom the clinical use is intended. The label for human prescription drugsrequires a good understanding of the pharmacological effects (pharmacodynamicsor PD) and the mechanism of action of the drug as well as detailed informationof the drug’s Pharmacokinetics (PK): … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 24 Apr 2015 · 7,158 accessesView PDF Cite

Research ArticleOpen accessIn the abstractGynaecologic NephrologyNaheed Ansari, Jolina Santos, Fuad Spath, Srujana PolsaniRenal issues are commonly encountered in females. They can occur both in pregnant and nonpregnant females. Many physiologic changes occur during pregnancy to accommodate the growing fetus. Pregnancy is characterized by changes in blood pressure and expansion of total body volume which results in high glomerular filtration rate. The common renal problems seen in pregnant females are hypertension, proteinuria with … …Current Research in Medicine, Vol. 3, Issue 2 · 4 Aug 2012 · 7,314 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAdiponectin mRNA Expression in the Cat (Felis domesticus)Angela L. Lusby, Stephen A. Kania, Joseph W. Bartges, Claudia A. KirkProblem statement: Adiponectin is a hormone expressed from adipose tissue in people, rodents and dogs. Adiponectin has anti-inflammatory action with beneficial effects on cardiovascular health and insulin sensitivity. With increasing fat mass, adiponectin concentrations paradoxically decrease. Adiponectin’s role in metabolism and diabetes mellitus is of interest in feline medicine because cats are susceptible to developing type II diabetes with weight … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 4 · 27 Dec 2010 · 7,784 accessesView PDF Cite