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584 results for “relationship study”
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Research ArticleOpen accessPhrase in the titleTheoretically Predicted Descriptors Based Quantitative Structure Activity Relationship Study of the Activity of Acridines Against B-16 MelanomaBahjat A. Saeed, Rita S. Elias, Sadiq M-H. Ismael, Kawkab A. HussainProblem statement: The probability of success and reducing time and coast in drug discovery process could be increased on the basis of QSAR techniques. The study involves the QSAR investigation of 20 bioactive acridines that have activity against Approach: Molecular descriptors, total energy, van der Waals volume, molecular volume, HOMO energy, HOMO-LUMO energy gap, polarizability, refractivity, bond angle of C8-N9-C2 … …American Journal of Applied Sciences, Vol. 8, Issue 8 · 18 Jul 2011 · 7,695 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleDesign, Synthesis, Biological Screening and Structure Activity Relationship Study of 4, 6-Dimethyl-2-(Substituted) Mercapto-3-(Substituted) Pyridines as Anti Tubercular AgentsMehul M. Patel, Mahesh T. ChhabriyaProblem statement: Tuberculosis is a leading global mortality factor which has not been effectively controlled, with 1.7 million deaths per year and 8.9 million new cases. Aerobic microbe Mycobacterium tuberculosis H37Rv (MTB) is the causative agent of tuberculosis. Although many active antitubercular agents have since been developed, drug resistance will continue to be a problem. Therefore, there is a clear … …American Journal of Infectious Diseases, Vol. 7, Issue 3 · 3 Nov 2011 · 7,432 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleDensity Functional Theory Based Quantitative Structure Activity Relationship Study of 2,5-Bis(1-Aziridinyl)-p-Benzoquinones with Lymphoid LeukemiaBahjat A. Saeed, Rita S. EliasProblem statement: QSAR techniques increase the probability of success and reduce time and coast in drug discovery process. The study presented QSAR investigation on 32 bioactive aziridinylbenzoquinones that have activity against lymphoid leukemia. Approach: Molecular descriptors, molecular weight, total energy, hardness, chemical potential, electrophilicity index, HOMO and LUMO energies were calculated. Initial geometry optimizations were carried out with the AM1 … …American Journal of Applied Sciences, Vol. 7, Issue 7 · 31 Jul 2010 · 7,216 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleAntiviral and Quantitative Structure Activity Relationship Study for Dihydropyridones Derived from CurcuminBahjat A. Saeed, Kawkab Y. Saour, Rita S. Elias, Najim A. Al-MasoudiProblem statement: Pyridones are known to have variety of biological activities like antitumor, antibacterial, anti-inflammatory and antimalarial activities. This study presents antiviral evaluation of dihydropyridones derived from curcumin, as well as curcumin for comparison. Approach: The compounds evaluated for their in vitro antiviral activities against the viruses: HIV-1, Bovin viral Diarrhea, Yellow Fever, Reovirus 1, Herpesvirus 1, Vaccinia, Vescular Stomatitis, … …American Journal of Immunology, Vol. 6, Issue 2 · 30 Jun 2010 · 8,154 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleAntitumor and Quantitative Structure Activity Relationship Study for Dihydropyridones Derived from CurcuminBahjat A. Saeed, Kawkab Y. Saour, Rita S. Elias et al.Problem statement: Pyridones are known to have variety of biological activities like antitumor, antibacterial, antiinflamatory and antimalarial activities. This study presented antitumor evaluation of dihydropyridones derived from curcumin, as well as curcumin for comparison. Approach: The compounds evaluated for a preliminary estimation of the in vitro tumor inhibiting activity against 11 of tumor cell lines by using Microculture Tetrazolium assay … …American Journal of Immunology, Vol. 6, Issue 1 · 31 Mar 2010 · 8,265 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Study of Relationship Marketing on Customer SatisfactionSheng Chung LoProblem statement: Developing a sound knowledge on the customers’ necessities and preferences and producing accordingly the companies can lower the chances of losing customers as well as remove negative attitude towards foreign attitudes towards foreign brands. Approach: The research works of different authors have been analysed for performing present a research work on this topic. The study compiles many research … …Journal of Social Sciences, Vol. 8, Issue 1 · 30 Jan 2012 · 10,344 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleRelationship between Architectural Outer Shape and Function of Buildings: Behaviour Study on Building Constructed in ChinaISSA. A.M. Al-Kahtani, Suhaib Yahya Kasim Al-DarziThe present study attempted to investigate the behaviour of some projects designed and constructed in China during the last decades from an architectural view point and their compatibility with respect to the relationship between the outer shape and function of the building. The study includes different groups of architectural works including; Culture architecture, Education architecture, Office architecture and Hotel architecture … …American Journal of Applied Sciences, Vol. 5, Issue 9 · 30 Sep 2008 · 7,085 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Study of the Relationship Between Schooling and Enterprises' Demands for TalentsChien-Hua WangProblem statement: In this study, job vacancies in accountancy were used as examples to explore the relationship between schooling and enterprises’ demands for talents. Data of job vacancies and demands in accountancy from 2005-2009 were obtained from the well-known 1111 Job Bank. Approach: The grey prediction of the grey theory was applied to predict possible number of job vacancies in … …Journal of Social Sciences, Vol. 6, Issue 3 · 30 Sep 2010 · 7,713 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleRelationship Between Blood Fibrinogen Concentration and Pathological Features of Cancer Patients: A 139-case Clinical StudyDa-Yong Lu, Xue-Liang Chen, Min Huang et al.Angiogenesis and coagulation are among the most consistent host responses to the presence of a malignant tissue. Pathological angiogenesis and coagulation are often occurred in patients with solid tumors, especially in the occurrence of neoplasm metastasis and as targets for anti-metastatic drugs such as antiangiogenesis agents, coagulation-mediated agents and anticancer drugs. Since fibrinogen (Fib) is the most abundant and key … …OnLine Journal of Biological Sciences, Vol. 7, Issue 1 · 4 Sep 2010 · 7,871 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePreliminary Study of Phylogenetic Relationship of Rice Field Chironomidae (Diptera) Inferred From DNA Sequences of Mitochondrial Cytochrome Oxidase Subunit ISalman A. Al-Shami, M.N. Siti Azizah, Che Salmah Md Rawi, Abu Hassan AhmadProblem statement: Chironomidae have been recorded in rice fields throughout the world including in many countries such as India, Australia and the USA. Although some studies provide the key to genera level and note the difficulty of identifying the larvae to species level. Chironomid researches have been hindered because of difficulties in specimen preparation, identification, morphology and literature. Systematics, phylogenetics … …American Journal of Applied Sciences, Vol. 6, Issue 5 · 31 May 2009 · 7,524 accessesView PDFCite