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9 results for “pharmacological investigations”

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Research ArticleOpen accessIn the keywordsAntimicrobial and Wound Healing Potentials of Vitis Vitigenia LeavesKrishna Murti, Manish Kaushik, Aditi Kaushik, Deepika PaliwalProblem statement: The investigation for possible antimicrobial and wound healing activity of ethanolic and aqueous extracts of V. Vitigenia L. leaves were performed. The antimicrobial activity of extract was studied against the 8 bacterial and 2 fungal strains using agar cup plate method. Approach: The wound healing effect of both the extract of V. Vitigenia L. leaves were evaluated by … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 4 · 21 Feb 2012 · 7,476 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Phytochemical Analysis of Hydrodistilled Essential Oils of Scots Pine (Pinus Sylvestris L.) Needles From Central KazakhstanKuralay Tuleshova, Margarita Ishmuratova, Asanali Aynabayev et al.This study presents a detailed phytochemical investigation of hydrodistilled essential oils extracted from the needles of Pinus sylvestris (Scots pine), collected from fifteen natural populations located in the Karaganda and Ulytau regions of Central Kazakhstan. The extraction was performed using hydrodistillation with hexane as a co-solvent, and the chemical composition of the oils was subsequently analyzed using gas chromatography–mass spectrometry … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 28 Nov 2025 · 2,696 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioactive Goniothalamin from Goniothalamus tapis with Cytotoxic PotentialKallaya Sangrueng, Saksri Sanyacharernkul, Sirinapa Nantapap et al.Goniothalamus (Annonaceae) is well known for the rich of styryllactone contents and these plants are famous for the potential to be applied as alternative biological activities. The chemical and biological investigations of Goniothalamus tapis is tested for anticancer activities. The research was processioned to extract, isolate, purify and elucidate structure from the leaves and twigs of G. tapis. The isolated … …American Journal of Applied Sciences, Vol. 12, Issue 9 · 4 Oct 2015 · 7,226 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn Vivo Neutralization of Naja nigricollis Venom by Uvaria chamaeOmale James, Ebiloma Unekwuojo Godwin, Idoko Grace OtiniUvaria chamae is a well known medicinal plant in Nigerian traditional medicine for the management of many diseases, but investigations concerning its pharmacological characteristics are rare. In this study, we evaluate its venom neutralizing properties against Naja nigricollis venom in rats. Freshly collected Uvaria chamae leaves were air dried, powdered and extracted in methanol. To study the antivenom properties, albino … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 8,421 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Dietary Kaempferia parviflora on Ischemic Brain Injury in the ratWathita Phachonpai, Sinthuporn Maharun, Supaporn Muchimapura et al.Problem statement: Stroke often causes irreversible neuronal damage and related behavioral deficits. The lack of effective and widely applicable pharmacological treatments for ischemic stroke patients may explain a growing interest in traditional plant medicines. We investigated the ability of consuming Kaempferia parviflora extract, a Thai medicinal plant reputed for neuroprotective effects against brain damage, reduced infarct volume and improve neurological … …OnLine Journal of Biological Sciences, Vol. 12, Issue 1 · 20 Mar 2012 · 9,088 accessesView PDFCite
Research ArticleOpen accessIn the abstractUterus-Relaxing Study of a Sudanese Herb (El-Hazha)Aimun Abdelgaffar Elhassan Ahmed, Robert Gaspar, Arpad Marki et al.Problem statement: The aim of this study is to investigate the pharmacological effects of the Methanolic-extract (AH2) of El-Hazha and its sub-fractions. Approach: These investigations were carried out on in vitro isolated uterus preparations from Non-Pregnant (NP) and Late-Pregnant rats (LP). In parallel displacement radio-ligand binding assay was performed for β-Adrenergic Receptors (β-ADR). Results: Showed that the herb and its … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 7,509 accessesView PDFCite
Research ArticleOpen accessIn the abstractA New Polyoxypregnane Glycoside from the Roots of Dregea volubilis (L.f) Benth. ex Hook. f and its Chondroprotective EffectSaksri Sanyacharernkul, Akanit Itghiarbha, Prachya Kongtawelert et al.Problem statement: Dregea genus (Asclepiadaceae) is well known for the rich of steroid pregnane contents and these plants are famous for the potential to be applied as alternative biological activities. Dregea volubilis is the only species of Dregea genus in Thailand. The chemical and biological investigations of this plant are interesting to bioassay-guided fractionation, particularly chondroprotective effect. Approach: The research … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 4 · 31 Dec 2009 · 7,455 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Intravenous Ketamine Administration on Blood Glucose Levels in Conscious RabbitsSuleiman I. Sharif, Hanan A. AbouazraProblem statement: The intravenous general anaesthetic ketamine has been shown to produce changes in blood glucose levels. It is important to study the pharmacological basis of such an effect. Approach: The influence of varying doses of ketamine administered intravenously was studied in conscious rabbits. Serum glucose was determined by blood glucose method using an enzymatic PAP250 kit. Results: Low doses … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 2 · 30 Jun 2009 · 9,945 accessesView PDFCite
Research ArticleOpen accessIn the abstractSerotonergic Properties of the Roots of Clerodendron capitatumSiddig Ibrahim Abdel Wahab, Abdel Wahab Hassan Mohamed, Osama Yousif Mohamed et al.The aim of this study is to investigate the pharmacological effects of the methanolic extract of Clerodendron capitatum, CC, (family verbenaceae). These investigations were carried out on isolated frog rectus abdominus muscle and rabbit aortic strips and jejunum and non-pregnant rat uterus pretreated with oestradiol. Results showed that CC did not demonstrate any contracting, relaxant or blocking effects on frog … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 4 · 31 Dec 2008 · 7,847 accessesView PDFCite