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14 articles for “pathological processes”
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Research ArticleOpen accessIn the keywordsAnti-Metalloproteinase-9 Activities of Selected Indonesian Zingiberaceae Rhizome Extracts in Lipopolysaccharide-Induced Human Vascular Endothelial Cells In VitroYantiProblem statement: Atherosclerosis is associated with chronic inflammation triggered by bacterial infection that activates the breakdown of extracellular matrix protein by matrix Metalloproteinases (MMPs). Zingiberaceae, a group of tropical food crops grown in Indonesia and other Southeast Asia regions, has been traditionally used for food coloring, seasoning, culinary and medicinal purposes. However, its efficacy as natural vascular protection has not … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 1 · 27 May 2011 · 7,869 accessesView PDFCite
Research ArticleOpen accessIn the abstractInverse Correlation Between α-Klotho and Diabetic Biomarkers in Type 2 Diabetes: A Cross-Sectional StudyYaser A.M Sulaiman, Moayad M. Al Anzy, Omeed Akbar Ali, Adnan M. IsmailEvidence suggests a link between diabetes and Klotho protein, demonstrated by reduced Klotho gene expression in individuals with diabetes, α- klotho the potential modulator of kidney health in DM. Klotho is primarily expressed in the kidneys and has an anti-inflammatory and antioxidant role, which may protect against the pathological processes that damage renal function in diabetes. Research conducted in Japan … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 2 Jul 2026 · 837 accessesView PDFCite
Research ArticleOpen accessIn the abstractCPF-Net: Cross-modal CT and Pathology Guided Feature Learning for CT-based Lung Cancer Subtype ClassificationPeizhi Tan, Debiao YanAccurate classification of lung cancer subtypes from CT images remains challenging due to the subtle radiological differences between adenocarcinoma (LUAD) and squamous cell carcinoma (LUSC). We propose CPF-Net, a deep learning framework that integrates CT and pathological information through a Linear Spatial Reduction Attention (LSRA) module. The framework processes whole slide images using a modified CTransPath architecture for pathological feature … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 23 Jan 2026 · 1,856 accessesView PDFCite
Review ArticleOpen accessIn the abstractFrom Health to Disease: Functional Insights of Scavenger Receptor Class B Type I in Lipid Metabolism and Disease PathogenesisSujina Simon Sailet, Poornima Ajay Manjrekar, Santosh Rai et al.Scavenger receptor class B type I (SR-B1) has caught considerable interest among the scientific community due to its pivotal role in several biological and pathological processes. It is a multifunctional integral membrane protein and multiligand receptor encoded by the SCARB1 gene. SR-B1 has a wide distribution, primarily in the liver as well as steroidogenic organs including the gonads and adrenal … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 11 Jul 2025 · 3,667 accessesView PDFCite
Research ArticleOpen accessIn the abstractAlgorithmization of Electrostatic Model for Solving the Direct Problem of ElectrographyTagirbek Gaidarbekovich Aslanov, Naur Zamirovich Ivanov, Shamil Shamil`evich Anudinov, Tatiana Vladimirovna KarlovaAn analysis of the creation and implementation of algorithms to control cardiological processes occurring in the cardiovascular system using software and hardware diagnostic systems is a required activity. This study considers ways to improve the methods of medical data processing using electronic diagnostic systems, relying on existing methods of mathematical simulation of human body states. This study describes the development … …Journal of Computer Science, Vol. 21, Issue 4 · 7 Mar 2025 · 5,330 accessesView PDFCite
Review ArticleOpen accessIn the abstractVLDL in Atherosclerosis: Variety of Mechanistic ImplicationsAnastasia Vladimirovna Poznyak, Victor Yurievich Glanz, Vasily Nikolaevich Sukhorukov et al.Very-Low-Density Lipoprotein (VLDL) particles play a pivotal role as precursors for Intermediate-Density Lipoprotein (IDL) and eventually transform into Low-Density Lipoprotein (LDL). These particles have been categorized based on size and particle charge. Various types of VLDL impact diverse physiological processes in the human body. The accumulation of VLDL, along with other triglyceride-rich lipoproteins, significantly contributes to the development of atherosclerotic … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 29 Jul 2024 · 4,308 accessesView PDFCite
Review ArticleOpen accessIn the abstractOverview of Vascular Smooth Muscle Cells, Endothelial Cells, and Macrophages Apoptosis During Atherosclerosis DevelopmentAnastasia Vladimirovna Poznyak, Varvara Alexandrovna Orekhova, Vasily Nikolaevich Sukhorukov et al.Atherosclerosis is a complex disease that has garnered significant attention from researchers studying its various aspects. Its pathogenesis involves a wide array of cellular and molecular components, as well as crucial mechanisms and processes crucial for cellular and organismal functioning. Atherosclerosis is considered a chronic inflammatory disease characterized by disrupted lipid metabolism, oxidative stress, and immune response. Apoptosis, a fundamental … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 5 Jul 2024 · 4,675 accessesView PDFCite
Review ArticleOpen accessIn the abstractCardiolipin in Pathology: Implications in AtherosclerosisAnastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Anton Yuvenalievich Postnov et al.Mitochondria are cell organelles whose main role is to generate the energy needed for cell biochemical reactions via oxidative phosphorylation. Cardiolipin is a phospholipid that is present in the inner mitochondrial membrane and other energy-transducing membranes. Mitochondrial structure largely depends on cardiolipin, as it is involved in the biogenesis of mitochondrial cristae, folds in the inner mitochondrial membrane designed to … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 23 Sep 2023 · 4,792 accessesView PDFCite
Research ArticleOpen accessIn the abstractMorphology and Histochemistry of the Corpus Luteum (CL) of Ovaries of Pregnant and Infertile CowsEvgeny Skovorodin, Svetlana Bogolyuk, George Bazekin et al.The purpose of our study is to study the functional morphology of the Corpus Luteum (CL) of the ovaries of pregnant and infertile cows in normal and pathological conditions. For that purpose, the ovaries of cows were examined after slaughter, histological and histochemical examination of the CL was carried out. For the antemortem examination of the ovary, the biopsy method … …American Journal of Animal and Veterinary Sciences, Vol. 15, Issue 4 · 23 Oct 2020 · 6,610 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Basic Elements of Life'sRaffaella Aversa, Victoria Petrescu, Antonio Apicella, Ion Tiberiu PetrescuThe four basic elements of life are: Oxygen, hydrogen, nitrogen and phosphorus. These four elements are found in abundance in both the human body and in animals. There are other elements that compose the human body, but the four we've highlighted participate in all life processes. Besides, these four elements make up ATP chains (molecule), which governs and controls the … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 17 Dec 2016 · 121,931 accessesView PDFCite