5 results for “pain sensitivity”

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Research ArticleOpen accessPhrase in the titleEffect of Intrahippocampal γ Aminobutyrate B Receptor on Pain Sensitivity during Estrous CycleMahnaz Taherianfard, Rohollah GhorbaniProblem statement: There is a relationship between sexual hormones and pain sensitivity and also a role for hippocampal GABAB receptor in nociception. Therefore, the aim of the present investigation was to evaluate the effect of intrahippocampal injection of GABAB receptor agonist (baclofen) and GABAB receptor antagonist (CGP35348) on pain sensitivity during the estrous cycle. Approach: Forty eight adult female rats … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 3 · 26 Nov 2011 · 7,342 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAn Induced Hematoma in Caudoputamen Nuclei in Rats Causes Central Pain when the Thalamus is also Implicated and the Central Sensitization is Reversed with GabapentinP. P. Lema, P. VachonProblem statement: The objective of this study was to evaluate pain sensitisation in rats following the induction of an intracerebral hemorrhage by injecting a collagenase solution in the caudoputamen nucleus of the right basal ganglia and to evaluate gabapentin as an analgesic for central pain. Approach: Thirty male Sprague-Dawley rats weighing between 175-300 g were used. In a first experiment, … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 1 · 10 Mar 2012 · 8,167 accessesView PDF Cite

Research ArticleOpen accessIn the abstractIn Vitro Interaction of 5-Hydroxytrptamine with Cytosolic Molybdenum Hydroxylases as a Potential Inhibitor for Initial Rates ActivitiesAbdullah M. Al-Mohizea, Abd El-Galil E. Amr, Mohamed A. Al-OmarProblem statement: The role of 5-HT has been investigated in many behavioral activities. Thus, studies using raphe lesion showed that 5-HT is involved in sleep, general activity levels, habituation, aggression, pain sensitivity and morphine analgesia, avoidance behavior, self-stimulation and water consumption. Approach: The metabolic interaction between serotonin (5- hydroxytrptamine) and indole-3-aldehyde and xanthine via aldehyde oxidase (EC 1.2.3.1) and xanthine … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 7,026 accessesView PDF Cite

Research ArticleOpen accessIn the abstractDiagnostic Utility of Nodular Gastritis in Children with Chronic Abdominal Pain Undergoing EndoscopySeddiqe Amini-Ranjbar, Nouzar NakhaeeThis study was aimed to describe the endoscopic picture and laboratory findings in children with chronic abdominal pain and to determine the utility of nodular gastritis in diagnosing HPI in these patients. This prospective study was done between November, 2004 and May, 2007. A total of 70 patients (36 male and 34 female) aged 3-14 years, underwent upper endoscopy. H-pylori … …American Journal of Agricultural and Biological Sciences, Vol. 3, Issue 2 · 30 Jun 2008 · 8,184 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEvaluation of Acute-phase Reactants, Immunologic Markers and other Clinical and Laboratory Parameters in Patients with Pneumonia and Non-pneumonic Lower Respiratory Tract InfectionsJulio Collazos, María del Mar Martínez, Fernando IzquierdoMore efficacious tools to distinguish pneumonia from other acute lower respiratory tract infections (OALRTI) in facilities where radiologic studies are not easily or rapidly available are desirable to select the patients who should undergo chest radiographs, to avoid unnecessary visits to the emergency wards of hospitals and to optimize health resources. To this end we analyzed the relevance of many … …American Journal of Infectious Diseases, Vol. 3, Issue 1 · 31 Mar 2007 · 7,083 accessesView PDF Cite