3 results for “nitrogen heterocyclic”

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Research ArticleOpen accessIn the keywordsAnticancer Activities of Some New Synthesized Thiazolo[3,2-a]Pyrido[4,3-d]Pyrimidine DerivativesAshraf M. Mohamed, Abdel-Galil E. Amr, Musaed A. Alsharari et al.Problem statement: This study describes the synthesis and anticancer activities of a new series of thiazolo[3,2-a]pyrimidines derivatives (2-7) using 3,5-bisarylmethylene-1-methyl-4- piperidone and 4-aryl-8-arylmethelene-6-methylpyrido[4,3-d]pyrimidine-2(1H)thiones as a starting materials. Approach: The antitumor activities of the newly synthesized compounds 4-7 were evaluated utilizing 60 different human tumor cell lines, representing leukemia, melanoma, lung, colon, brain, ovary, breast and prostate as well as kidney. … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 23 Aug 2011 · 10,093 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAnticancer Activity of Some New Synthesized Tetrahydroquinoline and Tetrahydrochromene Carbonitrile DerivativesUsama W. Hawas, Mohamed A. Al-Omar, Abd El-Galil E. Amr, Abu El-Ftouh G. HammamProblem statement: In continuation to our search for new heterocyclic chemistry based anticancer, the suggestion, synthesis, structure elucidation of some naphthalene, chromene and quinoline derivatives 3-7 were realized herein using 3-methylcyclohexanone 1 as a starting material. Approach: The antitumor activities of the newly synthesized compounds 4-7 were evaluated utilizing 60 different human tumor cell lines, representing leukemia, melanoma, lung, colon, … …American Journal of Applied Sciences, Vol. 8, Issue 10 · 14 Sep 2011 · 7,487 accessesView PDF Cite

Research ArticleOpen accessIn the abstractBiodegradation of Phenolic Compounds in Creosote Treated Wood Waste by a Composting Microbial Culture Augmented with the Fungus Thermoascus aurantiacusAbdel E. Ghaly, Bopeng Zhang, Deepika DaveProblem statement: Creosote is used as a wood preservative and water proof agent in railway sleepers, utility poles, buildings foundations and fences and garden furniture. It is a mixture of over 300 hydrocarbons which include 75% polycyclic aromatic hydrocarbons, 2-17% phenolic compounds and 10-18% heterocyclic organic compounds. Exposure to creosote may result in several health problems including damage to kidney, … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 26 Aug 2011 · 9,453 accessesView PDF Cite