12 results for “mutagenic”

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Research ArticleOpen accessEvery word in the titleMutagenic Screening of Crude Oil Fractions Using Modified Ames Test and Allium cepa (Linn) AssayOlufunsho Awodele, Alade Akintonwa, Sunday O. Olayemi et al.Problem statement: Crude oil which may be broadly characterized as paraffinic or naphthenic is a complex mixture of alkanes, cycloalkanes and aromatic hydrocarbons. About 500,000 workers are employed in crude oil exploration and production worldwide. There have been reports of occupational exposure during drilling, pumping and transportation of crude oil, including maintenance of equipment used for these processes. Thus, skin … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Jan 2010 · 8,629 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleAssessment of the Mutagenicity of Some Pharmaceutical EffluentsA. Akintonwa, O. Awodele, A. T. Olofinnade et al.Problem statement: The pharmaceutical industry is a major contributor to industrial wastes globally. Effluents from this industry are usually discharged into the environment and when not properly handled and disposed, they affect both human health and the environment. Approach: This study evaluated the mutagenic potentials of effluents from six pharmaceutical companies in the Lagos province of Nigeria using modified Ames … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 7,509 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleDetermination of the Mutagenicity of 2-aminoanthracene Using Chicken Hepatic S-9 FractionVladimir A. Chistyakov, Alexander V. Usatov, Aleksander I. Klimenko et al.The abundance of potential genotoxins makes it necessary to improve microbial test systems that allow to identify these substances quickly. At the same time, the methodology of metabolic activation of promutagens in vitro is very important. Microsomal preparations of rodents, which are generally used for that, have significant disadvantages associated with the potential health risks of the inducers of the … …OnLine Journal of Biological Sciences, Vol. 18, Issue 4 · 16 Nov 2018 · 7,192 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleIndications of Potential Toxic/Mutagenic Effects of World Trade Center Dust on Human Lung Cell CulturesConstantino G. Lambroussis, Barbara D. Soares, Sergio Perez et al.Problem statement: Respiratory complications have been linked with exposure to dust particulates after the tragedy of September 11th, 2001 at the World Trade Center (WTC) site. Approach: The purpose of these experiments was to investigate the extent of cellular damage resulting from WTC dust exposure. Results: This research project was conducted with human lung fibroblast cells exposed to WTC dust. … …OnLine Journal of Biological Sciences, Vol. 9, Issue 3 · 30 Sep 2009 · 7,394 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsThe Removal of Methyl Red from Aqueous Solutions Using Banana Pseudostem FibersMas Rosemal H. Mas Haris, Kathiresan SathasivamProblem statement: The aim of this study was to investigate the removal of methyl red, a mutagenic monoazo dye, from various aqueous solutions using banana pseudostem fibers of the size 212-350 micron. Approach: The parameters studied were the effect of pH, amount of adsorbent, contact time, concentration of adsorbate and agitation speed. Results: Equilibrium data were fitted to the Langmuir … …American Journal of Applied Sciences, Vol. 6, Issue 9 · 30 Sep 2009 · 8,298 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEffect of Cadmium on Worker Ovary Morphology of Bombus morio (Hymenoptera: Bombini)Fábio Camargo Abdalla, Marina Pedrosa, Caio Eduardo da Costa Domingues, Paulo José BalsamoBees are valuable bioindicators, providing information regarding environmental conditions through different kinds of analyses. Therefore, the effect of cadmium on the morphology of ovaries of Bombus morio workers was used to study a concentration considered environmentally safe (1 ppb) in Brazil. Workers of the same estimated age exposed for 48 h to 1 ppb cadmium showed extensive morphological changes in … …American Journal of Agricultural and Biological Sciences, Vol. 13, Issue 1 · 10 Apr 2018 · 9,140 accessesView PDF Cite

Research ArticleOpen accessIn the abstractChemical Mutagenesis for Improvement of Production of a Biologically Active Extracellular Polymeric Substance by Halomonas xianhensis SUR308Jhuma Biswas, Amal K. PaulA moderately halophilic bacterium, Halomonas xianhensis SUR308 (Genbank Accession No. KJ933394) isolated from solar saltern of Surala, Odisha, India was found to produce significant amount of a biologically active extracellular polymeric substances (EPS). Under optimized cultural conditions, the strain was able to produce 7.05 g L-1 of EPS after 8 days of incubation under shake culture. To enhance the EPS … …Current Research in Microbiology, Vol. 7, Issue 1 · 1 Apr 2016 · 15,918 accessesView PDF Cite

Review ArticleOpen accessIn the abstractSelected Genotoxic Impurities Profiling During WFI Qualification to Control Carcinogenesis in Large Volume ParenteralsMohabbat UllahWater For Injections (WFI) which is the main vehicle of Large Volume Parenterals (LVPs) should be free from trace amount of genotoxic impurities. This review gives emphasis on quantification of genotoxic trace metals during qualification of WFI in LVPs manufacturing unit. According to ICH guidelines, impurities related to drug substances are classified into three main categories: Organic impurities, inorganic (elemental) … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 27 May 2015 · 7,708 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAntioxidant and Antimutagenic Activities of Taif Grape (Vitis vinifera) CultivarsAbdelmegid Ibrahim Fahmi, Mohamed Ahmed Nagaty, Ahmed Mohamed El-ShehawiExtract of grape Vitis vinifera has been reported to exhibit antioxidant and antimutagenic activities and the phenolic compounds play a vital role in determining these activities. Therefore; the objective of the present study was to evaluate the antioxidant and anti-mutagenic activities as well as the phenolic composition of different grape cultivar extracts collected from Taif region. The grape cultivars namely; … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 2 · 20 Jun 2013 · 8,010 accessesView PDF Cite

Research ArticleOpen accessIn the abstractTartaric Acid Modified Rice Hull as a Sorbent for Methylene Blue RemovalSiew-Teng Ong, Pei-Sin Keng, Ai-Wen Chong et al.Problem statement: Improper dye discharge from various industries such as textile, paper, cosmetic and plastics into receiving streams can be one of the sources towards water pollution. The release of these effluents not only causes various disruptions in the ecosystems, but also poses hazard effect as most of the dyes are highly toxic, mutagenic and carcinogenic in nature. Approach: To … …American Journal of Environmental Sciences, Vol. 6, Issue 3 · 30 Jun 2010 · 7,151 accessesView PDF Cite