10 results for “multiplex PCR”

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Research ArticleOpen accessPhrase in the titleImpact of Multiplex PCR Panel on Reducing Broad-Spectrum Antibiotic Use in Ventilator-Associated PneumoniaMaría Inés Staneloni, Emilio F. Huaier Arriazu et al.The extended use of broad-spectrum antimicrobials contribute to the growing threat of antimicrobial resistance. This study evaluated the impact of a multimodal strategy aiming at reducing the duration of broad-spectrum antimicrobial therapy in Ventilator-Associated Pneumonia (VAP). Conducted in a single Intensive Care Unit (ICU), this quasi-experimental, retrospective study compares a pre-intervention period (08/01/2018-07/01/2019) with an intervention period (08/01/2022-07/01/2023). Adult patients … …American Journal of Infectious Diseases, Vol. 21, Issue 1 · 8 Jul 2025 · 6,589 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsGanoderma Species Associated with Basal Stem Rot Disease of Oil PalmLing-Chie Wong, Choon-Fah J. Bong, A. S. IdrisProblem statement: Basal Stem Rot disease (BSR) is one of the most serious diseases that have been causing major losses in the oil palm industry in Southeast Asia, especially in Malaysia and Indonesia. Several species of Ganoderma have been reported pathogenic to oil palm, however, the diversity and differentiation of the Ganoderma species were not widely studied and the identity … …American Journal of Applied Sciences, Vol. 9, Issue 6 · 19 Mar 2012 · 9,638 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsLack of Association of Glutathione S-transferase Gene Polymorphisms in Iranian Prostate Cancer SubjectsB. Sahar Ansari, R. Vasudevan, M. Mirinargesi et al.Problem statement: Glutathione S-transferase is super family genes that encode enzymes which involve in the detoxification of the cell and protects DNA from damage. Conflicting results was found in several studies in association with GSTT1 and GSTM1 gene polymorphisms and prostate cancer. In this study, we determined the association between the GSTT1 and GSTM1 gene polymorphism and prostate cancer in … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 1 · 31 Mar 2009 · 8,279 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsThrombophilic Genes Mutations in Women with Repeated In-Vitro Fertilization FailureNaglaa Fathy Al Husseini, Ahmad Y. Rezk, Mosad M. Odah et al.Problem statement: Thrombophilia has been recently implicated in early pregnancy loss and IVF implantation failure, by impairing the initial vascularization process occurring at implantation, which is necessary for a successful pregnancy. Approach: The aim of this study is to assess the presence possibility of mutation in thrombophilic genes [Factor V (FV) gene, Prothrombin (PT) gene and Methylenetetrahydrofolate Reductase (MTHFR) gene] … …Current Research in Medicine, Vol. 2, Issue 1 · 29 Mar 2011 · 7,667 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPrevalence of Chlamydia trachomatis and Neisseria gonorrhoeae infections in Republic of Korea: Impacts of Sex, Age, and Testing MethodHyeok-Jin Kwon, Sun-Gyu Kim, Junmin Lee et al.The prevalence of Sexually Transmitted Diseases (STDs) is increasing globally, necessitating a quick and accurate diagnosis method for appropriate treatment selection. An analysis of venereal diseases conducted at U2Bio (Jangwon Medical Foundation, Seoul, Republic of Korea) over a 2-year period showed that Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection rates were related to sex, age, and specimen type. We … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 4 · 29 Oct 2024 · 5,023 accessesView PDF Cite

Research ArticleOpen accessIn the abstractGlutathione S-transferase (T1 & M1) Null Genotypes as Risk Determinants in Sudanese for Developing Type Two Diabetes MellitusGaafar Mahmoud, Hisham Mohamed Abdelrahim, Abed Al Salam Aljahmany, Eltayeb Mohamed Ahmed TayrabGlutathione S-transferases (GSTT1 and GSTM1) are globular proteins responsible for the detoxification of xenobiotics and the prevention of oxidative damage. Functional polymorphisms of the antioxidant glutathione and enzymes have a role in the pathogenicity of T2DM and its complications. The present study is aimed to assess association between GSTM1 and GSTT1 genetic polymorphisms with T2DM in Sudanese people. This case-control … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 16 Oct 2020 · 6,426 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPrevalence of Escherichia Coli in Some Selected Foods and Children Stools with Special Reference to Molecular Characterization of Enterohemorrhagic StrainR. Farhan, S. Abdalla, H. A. Abdelrahaman et al.Escherichia coli is one of the most important etiologic agents of childhood diarrhea that represents a major public health problem in developing countries and now is being recognized as emerging entero-pathogens in the well developed countries. Among the diarrhegenic Escherichia Coli (DEC) this work was focused on the Enterohemorrhagic Escherichia Coli (EHEC) that produce Shigatoxins (Stxs). The infection is mainly … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 23 Dec 2014 · 7,878 accessesView PDF Cite

Research ArticleOpen accessIn the abstractUNUSUAL SPECTRUM OF GENETIC PATHOLOGIES AND NOVEL MUTATIONS IN PWS AND AS PATIENTS DETECTED BY A WIDE CLUSTER OF METHODSLivia Kotysova, Robert Petrovic, Jan ChandogaPrader-Willi and Angelman syndromes are clinically distinct neurodevelopmental genetic disorders that map to 15q11.2-q13 locus. The common phenotypes are attributable to loss of expression of parentally specific imprinted genes inside this region, where the gene function is dependent on parental origin. Initial diagnosis was proved for the years by methylation pattern analyses of the SNRPN exon 1/promoter region within the … …OnLine Journal of Biological Sciences, Vol. 14, Issue 3 · 12 Nov 2014 · 7,013 accessesView PDF Cite

Research ArticleOpen accessIn the abstractGenetic Characterization of a Bovine Breed (Tabapua) Under Artificial Selection Located in the Amazon RegionJose Elivalto Guimaraes Campelo, Marcone Helmer da Silva, Ednaldo da Silva Filho et al.Brazil currently has the biggest commercial bovine cattle population in the world. Several different breeds that come from Europe and India compose it. They are primarily used for dairy and meat production. In Brazil, several high quality genetic background cattle are kept in a condition known as pure breed, meaning no other animal of different genetic background is interbreeding with … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 4 · 30 Jan 2013 · 7,558 accessesView PDF Cite

Short CommunicationsOpen accessAll words, across the recordMolecular Testing for Respiratory Tract Infections May Have Favorable Impact on Real-world Healthcare CostsAzia Evans, Vijay Singh, Pallavi Upadhyay et al.Molecular testing by Polymerase Chain Reaction (PCR) has improved diagnostic performance to inform appropriate treatment. However, its impact on healthcare utilization and costs related to respiratory tract infections are yet to be studied in detail. The aim of this study is to evaluate the costs of healthcare utilization following traditional culture and molecular PCR diagnostic testing for respiratory tract infections. … …American Journal of Infectious Diseases, Vol. 20, Issue 3 · 15 Jan 2025 · 5,264 accessesView PDF Cite