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40 results for “multidrug resistant”
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Review ArticleOpen accessPhrase in the titleMultidrug Resistant Microorganisms (MDR) and Biofilm Producers: A Challenge for Hospital Infectious ControlDaniel Lucio, Elizabeth Proaño, Alberto Bustillos et al.Antimicrobial Resistance (AMR) now represents a major threat to contemporary health care, especially in hospitals, where repeated antimicrobial exposure selects for and facilitates the dissemination of Multidrug-Resistant (MDR) microorganisms. Biofilm growth adds another layer of persistence by increasing microbial tolerance, supporting long-term colonization of medical devices, and worsening clinical and economic outcomes. This narrative review synthesizes evidence on MDR biofilm-forming … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 3 · 12 Sep 2026 · 774 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleMultidrug Resistant Uropathogens among Egyptian Pregnant WomenWafaa Salah Metwally, Walid Mohamed ElnagarUrinary Tract Infections (UTIs) in pregnancy is a common medical problem associated with significant increase in the risk of fetal morbidity and mortality. The effective appropriate antimicrobial agent is a major concern as many effective antimicrobial groups cannot be used due to their potential toxicity to the fetus as well as the increasing rates of Multidrug-Resistant (MDR) strain isolation. This … …American Journal of Infectious Diseases, Vol. 15, Issue 4 · 21 Dec 2019 · 7,487 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleDiatrizoate, Iopromide and Iotrolan Enhanced Cytotoxicity of Daunorubicin in Multidrug Resistant K562/adr Cells: Impaired the Mitochondrial and Inhibited the P-Glycoprotein FunctionNitaya Snitwongse Na Ayudhya, Samlee MankhetkornMultidrug resistance was an obstacle in cancer chemotherapy because the cells decreased their intracellular drug accumulation by energy-dependent compounds efflux pumps such as P-glycoprotein (P-gp). This study observed some iodinated radiographic contrast media, diatrizoate, iopromide and iotrolan affected the cellular energetic state and the kinetics of P-gp in drug-sensitive K562 and drug resistant K562/adr cell lines using spectrophotometer and spectrofluorometer. … …American Journal of Applied Sciences, Vol. 6, Issue 3 · 31 Mar 2009 · 7,161 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleMechanistic Insights of Actions of Metal Nanoparticles on Multidrug-Resistant BacteriaSeham S. Alzahrani, Hani Mohammed Ali, Mohamed M. AhmedMultidrug-Resistant bacteria (MDR) are the most serious threat to public health. The number of infections caused by resistant strains is on the rise all over the world. At this time, new techniques for developing antimicrobial drugs are becoming necessary. Metallic Nanoparticles (MNPs) in the biomedical field are one of the most promising methods to overcome antibiotic resistance. Nanoparticles have recently … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 22 Jun 2021 · 6,374 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDetection of tet Gene in Multidrug-Resistant Salmonella spp. Isolates from Layers and Broiler BreedersAgustin Indrawati, Leila Nur Azizah, I Wayan Teguh Wibawan et al.The present study was conducted with the following aims: (i) To detect the multidrug-resistant Salmonella spp. isolates recovered from faeces, litter and drinking water in layers and broiler breeders’ farms and (ii) to carried out the detection of the tet gene. A total of 21 Salmonella isolates were subjected to Polymerase Chain Reaction (PCR) assay to determine the presence of … …American Journal of Animal and Veterinary Sciences, Vol. 15, Issue 2 · 17 Jun 2020 · 7,007 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Effect of a 4th Generation-Cephalosporin Introduction upon the Incidence of Multidrug-Resistant Gram-Negative Bacteria in a Non-Teaching HospitalGuilherme Henrique Campos Furtado, Luciana Baria Perdiz, Eduardo Alexandrino Servolo MedeirosProblem statement: Antimicrobial resistance is a worrisome situation in hospitals around the world and the misuse of certain classes of antimicrobials has contributed for this situation. Approach: We performed a prospective surveillance study on the incidence of multi-drug resistant bacteria before (phase 1) and after (phase 2) the introduction of a 4th-generation cephalosporin in a non-teaching hospital. Results: There was … …American Journal of Infectious Diseases, Vol. 4, Issue 4 · 31 Dec 2008 · 6,876 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIn Vitro Antimicrobial Activity of Modified Lysozyme (Lys 90) and Herbal Extracts Against Multidrug-Resistant Escherichia coliEni Kusumaningtyas, Bagem BR Sembiring, Andriani et al.The emergence of Antimicrobial Resistant (AMR) poses a significant challenge to the poultry farming industry. This study investigated the potential of Lysozyme (Lys), modified Lysozyme (Lys 90), an herbal extract, and their combination (herbs + Lys 90) as alternative antimicrobial agents against Multidrug-Resistant Escherichia coli (MDR-E. coli). Lys 90 was prepared by heating Lys at 90 °C for 20 minutes. … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 1 Dec 2025 · 2,076 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDominant Multidrug-Resistant Bacteria in Five Biggest Hospitals in Asir Region from March to June 2018Mohammed AlmaghrabiThere is a rapid increase in the emergence of multidrug resistance which consider as one of the public health threats in all over the world. MDR was defined as acquired non-susceptibility to at least one agent in three or more antimicrobial categories. The present study aims to determine the dominant multi-drug resistant bacteria in the five biggest hospitals in Asir … …American Journal of Infectious Diseases, Vol. 17, Issue 1 · 9 Mar 2021 · 6,782 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMultidrug-Resistant Bacterial Pathogens Assessment in Canine Ophthalmic InfectionsRicardo Antonio Pilegi Sfaciotte, Lincoln Garcia Coronel, Alessandra Snak et al.The objective of this study was to identify the main microorganisms associated with ophthalmic infections and determine the resistance profile of these isolates against antimicrobial drugs. 26 bacterial isolates from 18 canine ophthalmic infections were submited to the phenotypic resistance profile for 36 drugs of 12 classes of antimicrobials, research of multidrug-resistant strains with importance in public health and detection … …American Journal of Animal and Veterinary Sciences, Vol. 13, Issue 1 · 2 Jan 2018 · 7,275 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCirculation of Multidrug-Resistant (MDR) and Extensively Drug-Resistant (XDR) Mycobacterium Tuberculosis Strains in MexicoCarlos A. Vazquez-Chacon, Armando Martinez-Guarneros, Susana Balandrano Campos et al.Emergence of Extensively Drug-Resistant (XDR) Tuberculosis (TB) is an important public health problem worldwide. In Mexico, the extent of circulation of XDR-TB strains is unknown. Here, the drug-resistance patterns of TB isolates collected in Mexico between 2006 and 2008 were analyzed. Among 137 TB isolates, (58%) were classified as MDR exclusively, (33%) were Pre-XDR and (9%) were assigned as XDR. … …American Journal of Infectious Diseases, Vol. 10, Issue 4 · 7 Jan 2015 · 7,422 accessesView PDFCite