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Research ArticleOpen accessEvery word in the titleInduced Microcracking Affects Osteoblast Attachment on Hydroxyapatite Scaffolds for Tissue EngineeringIan O. Smith, Melissa J. Baumann, Eldon D. CaseBone microdamage caused by routine activity plays an important role in triggering targeted and nontargeted bone remodeling. Targeted remodeling occurs near localized areas of microdamage[1-4]. We hypothesize that bone remodeling may be directly and positively influenced by inducing microcracks in hydroxyapatite (HA) scaffolds for bone tissue engineering. A study by Case et al. showed microcracking in HA discs having >98% … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 3 · 30 Sep 2006 · 6,557 accessesView PDF Cite

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