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28 results for “human bone”

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Research ArticleOpen accessPhrase in the titleClozapine and its Major Stable Metabolites, N-desmethylclozapine and Clozapine N-oxide do not Affect Human Bone Marrow Stromal Cells in vitroAvril Pereira, Brian DeanTreatment of refractory schizophrenia with the atypical antipsychotic drug clozapine is associated with life-threatening agranulocytosis, characterised by a drop in neutrophil count. Theoretically, toxicity may be accounted for by direct action of parent drug or one of its stable metabolites on bone marrow stroma given importance of these cells to neutrophil maturation. Effects of clozapine, N-desmethylclozapine and clozapine N-oxide on … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 1 · 31 Mar 2006 · 7,111 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Effect of the Bone-Plate Whole Spacing on the Interfragmentary StrainBoonthum WongchaiProblem statement: The bone plate is commonly used when human bone fracture occurs. The Inter Fragmentary (IFS) is an important factor for curing human bone fracture and designing the bone plate. The best IFS range from 2-10%.The whole spacing is a factor affecting the IFS that should be taken into account. Approach: This research propose a study on the effect … …Journal of Computer Science, Vol. 8, Issue 1 · 3 Nov 2011 · 6,882 accessesView PDFCite
Case ReportOpen accessIn the keywordsHistopathology of Microbially Induced Corrosion and Cluster Failure of Moderately Rough Surface Oral Implants in a Resident Bone MicrobiotaStephen Nelson, Helen Hu et al.This case report presents as a maxillary "cluster-failure", where six moderately rough-surface oral implants (1-2 microns) were installed to support a full-arch hybrid bridge. Understanding cluster failures requires the acknowledgment of biofilm science that recognizes the persistence of bacterial infection in bone following extraction and the need to bioremediate the bone-bed, by surgical debridement, before implant installation. The patient, a … …Current Research in Dentistry, Vol. 15, Issue 1 · 28 Feb 2024 · 8,486 accessesView PDFCite
Research ArticleOpen accessIn the abstractCytocompatibility and Antimicrobial Properties of Silver Nanoparticles-Loaded AMPs in the Oral CavityYanli Lv, Weikai ZhangPostoperative infection following oral metal implantation is a key factor that affects the success rate of surgery. This infection is mainly caused by bacterial biofilms. Traditional single antibacterial coatings have limitations, including a narrow antibacterial spectrum and poor cytotoxicity or stability. This study combined silver nanoparticles (AgNPs) and the synthetic antimicrobial peptide GL13K using electrostatic self-assembly technology to create a … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 24 Apr 2026 · 1,688 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Role of Living, Resident Bacterial Biofilm Populations in the Osseointegration of Oral ImplantsStephen Nelson, Honghua Hu et al.This study presents a human jawbone model which explains bone health, disease and quality and the osseointegration interphase, at the cell level. Curation of 454 pyrosequencing data obtained from 153 bone, serous-effusion and granulation samples taken from 40 patients during two-stage dental implant installation, revealed a 20 phyla jawbone microbiome with total genera of 387. Multivariate statistical ordination of curated … …Current Research in Dentistry, Vol. 14, Issue 1 · 16 Nov 2023 · 8,251 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Electronic Cigarette E-Liquids on the Adhesion and Growth of Osteoblast CellsAna Carla Lorenz-Vieira, Cesar Augusto Magalhães Benfatti, Mahmoud RouabhiaElectronic cigarettes (E-cigarettes) were designed to replace traditional cigarettes to decrease the harmful effects of smoking. The liquid in e-cigarettes contains different chemicals, such as Propylene Glycol (PG) and Vegetable Glycerin (VG), and may contain nicotine. To be more attractive, e-liquids are supplemented with flavorings. Because vaped e-liquids are shown to be damaging to oral tissues, similar effects could occur … …OnLine Journal of Biological Sciences, Vol. 23, Issue 3 · 29 Apr 2023 · 5,160 accessesView PDFCite
Review ArticleOpen accessIn the abstractMedical Service of RobotsRelly Victoria Virgil PetrescuToday, robots have not only penetrated to create microchips in electronics but also in medicine, where it helps to perform difficult operations, especially where precision is needed and the size is small and any human error could be fatal to the patient. Robots assist the doctor in heart, brain, kidney operations, not to mention bone implants and repair of damaged … …Journal of Mechatronics and Robotics, Vol. 3, Issue 1 · 24 Apr 2019 · 7,549 accessesView PDFCite
Research ArticleOpen accessIn the abstractMechanically Stimulated Osteoblast Cells GrowthRaffaella Aversa, Antonio Apicella, Francesco Tamburrino, Florian Ion Tiberiu PetrescuThe bones need to be built and then permanently restored to keep them functioning properly. Considering the multiple bone functions, their vitality is essential both to maintain the body and move it and to maintain its health and vigor. When most bones begin to age and have no vital function, the man also begins to age, lose water, minerals, electrolytes, … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 2 · 19 Jun 2018 · 7,888 accessesView PDFCite
Research ArticleOpen accessIn the abstractAbout the Internal Structure of a Bone and its Functional RoleAntonio Apicella, Raffaella Aversa, Francesco Tamburrino, Florian Ion Tiberiu PetrescuThe human skeleton has the primary role of supporting all the organs that make up the body and at the same time to protect them permanently. It is made up so that it can hold and hold together all internal human organs, protecting them permanently, but also allowing them to move and exercise all their functionalities. This paper wants to … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 2 · 26 May 2018 · 8,409 accessesView PDFCite
Research ArticleOpen accessIn the abstractStress Analysis of an Artificial Human Elbow Joint: Application of Finite Element AnalysisStephen K. ArmahThe elbow joint is frequently affected by two kinds of arthritis (degenerative arthritis and rheumatoid arthritis) following some kind of injuries. There have been efforts since the eighteenth century by various individuals and organizations in modeling permanent implants for the elbow joint, but some of the prostheses have been disappointing because of lack of understanding of the biomechanics of the … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 1 · 4 Jan 2018 · 9,540 accessesView PDFCite