5 results for “heroin abuse”

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Research ArticleOpen accessIn the keywordsObservations on the Relationship between Opioid Medications, Illicit Drugs and Heroin Use in Pain PatientsDavid AlanYee, Michelle Marie Hughes, Rabia Samady Atayee et al.Problem statement: Patients on chronic opioid therapy are monitored to detect illicit drug use in order to deter diversion of their prescription opioids and to ensure medication adherence. The addictive potential of opioid drugs and their similar binding sites in the brain may make them potential gateway drugs for each other. Recent reports indicate that oxycodone has a high probability … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 1 · 7 Jun 2011 · 7,961 accessesView PDF Cite

EditorialOpen accessIn the abstractNaloxone as a Harm Reduction Initiative: Misinterpretations of ResearchRichard R. MassattiIn the American Medical Journal, Annahita Beheshti and colleagues review the literature on naloxone use for opioid overdose in West Virginia (Beheshti et al., 2015). The authors cite several of my publications in support of their views on naloxone (Massatti, 2013; Massatti et al., 2014), but many of these citations misinterpret my work by using it to present a counterargument … …Current Research in Medicine, Vol. 7, Issue 1 · 9 Apr 2016 · 8,033 accessesView PDF Cite

Research ArticleOpen accessIn the abstractOpiates Upregulate Adhesion Molecule Expression in Brain MicroVascular Endothelial Cells (BMVEC): Implications for Altered Blood Brain Barrier (BBB) PermeabilityMadhavan P.N. Nair, Supriya D. Mahajan, Jessica L. ReynoldsThe blood-brain barrier (BBB) is an intricate cellular system composed of vascular endothelial cells and perivascular astrocytes that restrict the passage of immunocompetent cells into the central nervous system (CNS). Expression of the adhesion molecules, intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) on brain microvascular endothelial cells (BMVEC) and their interaction with human immunodeficiency virus (HIV-1) … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,614 accessesView PDF Cite

Review ArticleOpen accessAll words, across the recordAn Evaluation of Naloxone Use for Opioid Overdoses in West Virginia: A Literature ReviewAnnahita Beheshti, Landyn Lucas, Tanika Dunz et al.Naloxone is a common treatment option for the reversal of an opioid overdose. The law regulating naloxone varies from state to state and therefore so does the drug’s availability. The state of Rhode Island has legalized naloxone for over-the-counter use while a number of states allow prescriptions to opioid abusers and family members. The medical community as a whole appears … …Current Research in Medicine, Vol. 6, Issue 1 · 9 Jul 2015 · 9,046 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordNeuroendocrine Abnormalities in Drug Abusers and HIV-Infected Individuals: Cortisol Response to Cold Pressor ChallengeMahendra Kumar, Drenna Waldrop-Valverde, Adarsh M. Kumar et al.Although endocrine abnormalities have been reported in HIV-1 infection, the role of risk factors is not understood. Injecting drug use (IDU) is an important risk factor for contracting HIV-infection and studies suggest that substance use may also be associated with endocrine dysfunction. In order to investigate hypothalamic pituitary adrenal (HPA) axis activity in this population, this study investigated cortisol response … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,597 accessesView PDF Cite