2 results for “four-color flow cytometry”

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Research ArticleOpen accessIn the keywordsCo-expression of Apoptosis-Related Molecules on Activated CD8+ CD38+ T-cells is Associated with HIV-1 Disease ProgressionJosé W. Rodríguez, Luis A. Rodríguez, Griselle Font et al.CD8+ T cells play a major role in controlling HIV-1 infection through the release of soluble lytic and non-lytic antiviral factors. Their decrease or defective function contributes to the HIV-1 disease progression. HIV-1 disease progression has been associated with a remarkable increase of CD38 expression on CD8+ T-cells. It has been also documented that a significant distribution of HIV-specific CD8+T-cells … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,009 accessesView PDF Cite

Research ArticleOpen accessIn the abstractHyper-Ag-specific Ab Production in NC/Nga Mice is not associated with Deletion Polymorphism in the Promotor Region of the FcγRIIB GeneTohru Sakai, Mariko Nakamoto, Emi SutoProblem statement: NC/Nga (NC) mice produced high levels of ovalbumin (OVA)-specific IgG, IgG1 and IgG2a. We previously found deletion polymorphisms in the promoter region of fcgr2b in NC mice. To determine whether this mutation causes a hyper-humoral immune response, we generated congenic BALB/c mice carrying the NC-type fcgr2b allele (NC fcgr2b) and analyzed humoral immune response and FcγRIIB on germinal … …American Journal of Immunology, Vol. 5, Issue 3 · 31 Dec 2009 · 7,364 accessesView PDF Cite