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7 results for “elevated plus maze”
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Research ArticleOpen accessIn the keywordsEffects of Aluminium Chloride on Anxiety-Related BehaviourA.A. Buraimoh, S.A. Ojo, J.O. Hambolu, S.S. AdebisiProblem statement: Aluminium is presents in many manufactured foods, medicines and is also added to drinking water for purification purposes. It has the potential to be neurotoxic in human and animals but its contribution in Alzhemer’s disease remains contradictory. Anxiety affects one-eighth of the total population world-wide and has become an important area of research interest in psychopharmacology. Approach: The … …Neuroscience International, Vol. 2, Issue 2 · 27 Feb 2012 · 7,966 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEvaluation of the Anxiolytic and Antidepressant Effects of Alcoholic Extract of Kaempferia parviflora in Aged RatsJintanaporn Wattanathorn, Prasert Pangpookiew, Kittisak Sripanidkulchai et al.To date, the search for novel pharmacotherapy from medicinal plants for psychiatric illnesses has significantly progressed. The present study was performed to evaluate the anxiolytic and antidepressant like activities of the K.parviflora rhizome extract. Aged male Wistar rats were orally administered the alcoholic extract of this plant at various doses ranging from 100, 200 and 300 mg kg-1 BW once … …American Journal of Agricultural and Biological Sciences, Vol. 2, Issue 2 · 30 Jun 2007 · 9,971 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIntranasal Administration of Quercetin Liposome Decreases Anxiety-like Behavior and Increases Spatial MemoryJintanaporn Wattanathorn, Wathita Phachonpai, Aroonsri Priprem, Saengrawee SuthiparinyanontAt present, the effects of quercetin liposome on anxiolytic activity and cognitive function are unclearly known. In this study, male Wistar rats were administered quercetin liposome via intranasal route once daily continually for 4 weeks. The anxiolytic activity and cognitive enhancing effect were determined after single administration, 1, 2, 3 and 4 weeks of treatment using elevated plus maze test … …American Journal of Agricultural and Biological Sciences, Vol. 2, Issue 1 · 31 Mar 2007 · 9,091 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Acute Toxicity and Neuropharmacological Activities of PM-52Wipawee Thukhum-Mee, Jintanaporn Wattanathorn, Supaporn MuchimapuraThe neuropsychological disorders are increasing their importance nowadays. Unfortunately, the therapeutic efficacy is still not in satisfaction level. Therefore, the novel agents that are effective, safe, cheap and easy to approach are in required. Therefore, we aimed to determine the neuropharmacological activities of PM52, the novel herbal supplement. We had developed the PM52, a novel product comprising of Cissampelas pariera … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 2 · 27 May 2013 · 7,351 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Neuropharmacological Activities of Stephania venosa Herb Consumption in Healthy RatsTerdthai Tong-Un, Wathita Phachonpai, Supaporn Muchimapura et al.Public concern on mental health has noticeably increased given the high prevalence of neuropsychiatric disorders especially anxiety and depression. Most of the drugs for these conditions used nowadays have adverse side effects so the need for newer, better-tolerated and more efficacious treatments is remaining high. Growing attention is being paid to traditional herbal medicines. Stephania venosa Spreng (S. venosa; SV) … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 3 · 5 Jul 2012 · 7,677 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of Neuropharmacological Activities of Terminalia Chebula in RatsWathita Phachonpai, Jintanaporn Wattanathorn, Terdthai Tong-un et al.Problem statement: Oxidative stress has been implicated in the pathophysiology of many neurodegenerative diseases such as Alzheimer’s Disease (AD). In traditional practices of Ayurvedic medicine, numerous herbs have been used to treat cognitive disorders. Terminalia Chebula (Combretaceae; TC), is a well-known Ayurvedic herbal remedy which possesses an antioxidant activity. The scientific literature strongly supports its in vitro exerted acetylcholinesterase inhibitory … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 2 · 11 Jun 2012 · 8,295 accessesView PDFCite
Research ArticleOpen accessIn the abstractQuercetin Liposomes via Nasal Administration Reduce Anxiety and Depression-Like Behaviors and Enhance Cognitive Performances in RatsTerdthai Tong-Un, Panakaporn Wannanon, Jintanaporn Wattanathorn, Wathita PhachonpaiProblem statement: At present, the prevalence of neuropsychological disorders particularly anxiety, depression and dementia are increase. Many strategies have been developed in order to increase the efficiency of treatment and decrease side effects. Oxidative stress has been reported to play an important role on various path physiological states. Quercetin is a flavonoid commonly found in fruits and vegetables. It has … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 9,034 accessesView PDFCite