3 results for “dopaminergic receptors”

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Research ArticleOpen accessEvery word in the titleInvolvement of Microsomal Na+/K+ ATPase Activity in the Mechanism of Action of Dopaminergic D2 ReceptorsAbdulrahim Abu-JayyabProblem statement: Our previous research has shown that mitochondrial ATPase may have a role in the action of dopaminergic D2 receptors. It is therefore, thought of interest to investigate the effect of bromocriptine, sulpiride or their combination on the mitochondrial and microsomal ouabain sensitive and ouabain insensitive Na+/K+-ATPase in the liver of rats. Approach: In vivo treatment was carried out … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 6,974 accessesView PDF Cite

Research ArticleOpen accessIn the abstractDifferent Arrangement of Dopamine Receptors/NMDA Receptors Heterocomplexes in the Brain Regions of a Healthy Male, Female and Audiogenic Seizure-Prone Male RatsGigi Tevzadze, Elene Zhuravliova, Natia Okriashvili et al.Differences in the composition and subcellular localization of heteroreceptors in the brain can trigger central nervous system diseases, including epilepsy and autism. Protein-protein interactions between Dopamine Receptors (DRs) and GLUN2A and GLUN2B subunits are critical mechanisms that regulate dopamine and glutamate coordinated signals. These interactions may be involved in the pathophysiological predisposition of epilepsy. We hypothesized that the specificity of … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 2 · 27 Apr 2022 · 6,104 accessesView PDF Cite

Research ArticleOpen accessIn the abstractTaurine Implicated in Bromocriptine Induced Hallucination: Glycine-Glutamic-Aspartic Implicated in Bromocriptine Induced SchizophreniaAbdulrahim Abu JayyabProblem statement: The literature is reviewed and supports a strong anecdotal relationship between bromocriptine use and psychosis. It is well known that any interference with brain amino acid levels is likely to lead to disorder. Our previous research has shown that bromocriptine produced significant changes in the heart and kidneys amino acid contents. It has been confirmed that the brain … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Mar 2010 · 8,037 accessesView PDF Cite