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Research ArticleOpen accessIn the keywordsDetection of HCV Components and Pathological Reactions in Apoptotic Hepatocytes from Chronically HCV-infected PatientsViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.Analysis of Hepatitis C Virus (HCV)-infected hepatocytes at the cellular level may contribute to elucidate the mechanisms of HCV pathogenesis. In this work, the presence of HCV components and pathological reactions in apoptotic hepatocytes from chronic HCV-infected patients were studied by electron microscopy and confocal microscopy. Eight samples of liver biopsies from patients with chronic hepatitis C were studied by … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,907 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffect of Lead on the Chlorophyll and Antioxidant Response in the Leaves of Arabidopsis thalianaJun Xing, Cailing Yuan, Hui Yu et al.Lead (Pb) is a non-essential heavy metal element for plants. In this study, the effect of 0.025, 0.05, 0.1, 0.25, and 0.5 g/L Pb on the chlorophyll and antioxidant response was analyzed in the leaves of Arabidopsis thaliana. The results indicate that 0.025 g/L Pb had no significant effect on the fluorescence intensity of chlorophyll. However, 0.05, 0.1, 0.25, and … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 1 · 31 Mar 2024 · 4,628 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEvidences of Apoptosis in Hepatitis C Virus-Infected Hepatocytes and Peripheral Blood Monocuclear Cells in the Absence of Liver InjuryViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.Understanding the mechanism of Hepatitis C Virus (HCV) pathogenesis is an important part of HCV research. In this study, the presence of apoptosis in HCV-infected liver and Peripheral Blood Mononuclear Cells (PBMC) from patients positive for anti-HCV antibodies and negative for serum HCV-RNA was investigated. The samples obtained from 21 patients were studied by in situ Hybridization (ISH), Immunofluorescence, TUNEL … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,975 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEvidences of Hepatitis C Virus Replication in Hepatocytes and Peripheral Blood Monocuclear Cells from Patients Negative for Viral RNA in SerumViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.In this study, we examined the expression of hepatitis C virus (HCV) components in hepatocytes and peripheral blood mononuclear cells (PBMC) from patients positive for anti-HCV antibodies and negative for serum HCV-RNA. The samples obtained from 25 randomly selected patients (13 of 25 patients showed no histological evidences of chronic hepatitis and had normal serum ALAT and GGTP levels) were … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 7,164 accessesView PDFCite
Research ArticleOpen accessIn the abstractAccumulation and Effect of Manganese on Chloroplasts and Antioxidant Responses in Arabidopsis ThalianaJun Xing, Xue Yang, Cailing YuanIn this study, 5-day-old seedlings of Arabidopsis thaliana were exposed to 0, 0.5, and 1.0 mmol/L MnCl₂ for 6 days by using three independent biological replicates. The results indicated that Mn content in roots exhibited a dose-dependent increase with rising external Mn supply. The elevated Mn levels led to significant reductions in the nutrient content of K, Ca, Na, and … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 18 Jul 2026 · 824 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Mercuric Ion on the Oxidant Response and Calcium Ion in the Protoplasts of Arabidopsis ThalianaJun Xing, Rui Wu, Hui Yu et al.As a non-essential element for plant growth and development, the heavy metal mercury (Hg) has significant toxicity to plants. The aim of this study was to investigate the effect of mercuric ion (Hg2+) on the oxidant response and calcium ion (Ca2+) in the protoplasts of Arabidopsis thaliana. The protoplast cells were exposed to 5.0, 10.0, and 20.0 mmol/L Hg2+ for … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 29 Aug 2023 · 4,961 accessesView PDFCite
Research ArticleOpen accessIn the abstractSelective Susceptibility of Human Bladder Transitional Cell Carcinoma T24 Cells towards NBD PeptideSankari Durairajan, Charles Emmanuel Jebaraj Walter, Kalaiselvi Periyandavan et al.Bladder cancer is a recurrent disease that often develops chemoresistance and is on the rise in developing countries. After diagnosis surgery followed by immunotherapy and/or chemo- radiation therapy are the available treatments. These treatments do not provide protection against disease progression or recurrence thus highlighting the need to identify and develop drugs that are capable of inhibiting bladder cancer. T24 … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 20 Apr 2020 · 7,787 accessesView PDFCite
Research ArticleOpen accessIn the abstractPotential of HMEC-1 Line and HUVEC Primary Culture Cells to Study the Neonatal IgG Fc Receptor in vitroLuz Belinda Ortiz-Alegría, Irma Cañedo-Solares, Felipe Vadillo-Ortega et al.The neonatal IgG Fc receptor (FcRn) plays an important role in IgG homeostasis and immunity passive transfer. Fine points regarding these mechanisms, however, are still emerging. In order to obtain information about these phenomena, it is essential to have in vitro models of endothelium that express this receptor. In this study we chose two widely used models of human endothelial … …American Journal of Immunology, Vol. 12, Issue 1 · 21 Mar 2016 · 9,446 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Clean-Green Synthesis of Platinum Nanoparticles Utilizing a Pernicious Weed Lantana (Lantana Camara)Musthafa O. Mavukkandy, Sudip Chakraborty, Tasneem Abbasi, Shahid A. AbbasiA rapid, reproducible single step method is proposed for synthesizing platinum nanoparticles using an invasive weed lantana (Lantana camara, L). The method involves mixing of platinum (VI) solution, lantana leaf extract and ascorbic acid in appropriate concentrations and keeping the mixture at 95°C for 8 min. The collective action of ascorbic acid and leaf extract reduced the chloroplatinic acid to … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 1 · 23 Feb 2016 · 10,447 accessesView PDFCite
Research ArticleOpen accessIn the abstractRal-Binding Protein is Required for the Maturation and Function of Dendritic CellsJozef Borvak, Mukesh Sahu, Varun Joy et al.Problem statement: Dendritic Cells (DCs) integrate responses of innate and adaptive immune system via transmitting pro-inflammatory and regulatory signals to naïve cells within draining lymph nodes. DCs have high capacity for endocytosis, both Clathrin-Dependent (CDE) and Caveolin-Dependent (CvDE). Approach: We have recently shown that ATP-hydrolysis by the multifunctional transporter protein RLIP76 is the primary determinant of the rate of CDE. … …American Journal of Immunology, Vol. 6, Issue 3 · 13 Sep 2010 · 8,095 accessesView PDFCite