8 results for “chromosomal aberrations”

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Research ArticleOpen accessIn the keywordsAntioxidant and Antimutagenic Activities of Taif Grape (Vitis vinifera) CultivarsAbdelmegid Ibrahim Fahmi, Mohamed Ahmed Nagaty, Ahmed Mohamed El-ShehawiExtract of grape Vitis vinifera has been reported to exhibit antioxidant and antimutagenic activities and the phenolic compounds play a vital role in determining these activities. Therefore; the objective of the present study was to evaluate the antioxidant and anti-mutagenic activities as well as the phenolic composition of different grape cultivar extracts collected from Taif region. The grape cultivars namely; … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 2 · 20 Jun 2013 · 8,010 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsGenotoxic Profile of Motor Garage WorkersNandan M. Shastri, Hemlata PantProblem statement: One way to study the effects on an exposed population is to conduct monitoring studies, using relevant biological parameters with a short term manifestation, such as cytogenetic analysis express the damages to the DNA or to the chromosomes resulting from exposure can be identified. The present study was thus designed to elucidate the effect motor garage environment on … …American Journal of Infectious Diseases, Vol. 7, Issue 3 · 15 Oct 2011 · 8,001 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsAnalysis of the Cytogenetic Status, Genome Instability, and Adaptive Potential of the Kazakh Tobet DogOksana Cherednichenko, Anastassiya Pilyugina, Dinara Azizbekova et al.In recent years, interest in indigenous dog breeds has increased. The Tobet is a unique breed of Kazakh livestock guardian dogs adapted to nomadic pastoralism that developed over thousands of years across Central Asia and Turkestan. Currently, the Tobet breed faces critical endangerment. Its conservation and sustainable breeding require thorough analysis of hereditary characteristics, genome stability, and adaptive potential. In … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 4 · 19 Feb 2026 · 1,891 accessesView PDF Cite

Research ArticleOpen accessIn the abstractProtective Effect of Curcumin Against Hepatic Toxicity Induced by Lithium Carbonate (Li2 Co3)Gehan B.A. Youssef, Ahlam F. Hamoda, Rabab R. Elzoghby et al.The current work was done on four groups of rats (10 for each) to detect the hepato-protective characters of curcumin on the toxicity induced by lithium carbonate. The oral administration of Li2 Co3 for one-month lead to noticeable decrease in the SOD, CAT and GSH while the increase in the GPx and some histological changes in the portal tissues including … …American Journal of Pharmacology and Toxicology, Vol. 14, Issue 1 · 31 Jul 2019 · 7,603 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMutagenic Screening of Crude Oil Fractions Using Modified Ames Test and Allium cepa (Linn) AssayOlufunsho Awodele, Alade Akintonwa, Sunday O. Olayemi et al.Problem statement: Crude oil which may be broadly characterized as paraffinic or naphthenic is a complex mixture of alkanes, cycloalkanes and aromatic hydrocarbons. About 500,000 workers are employed in crude oil exploration and production worldwide. There have been reports of occupational exposure during drilling, pumping and transportation of crude oil, including maintenance of equipment used for these processes. Thus, skin … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Jan 2010 · 8,629 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAssessment of the Mutagenicity of Some Pharmaceutical EffluentsA. Akintonwa, O. Awodele, A. T. Olofinnade et al.Problem statement: The pharmaceutical industry is a major contributor to industrial wastes globally. Effluents from this industry are usually discharged into the environment and when not properly handled and disposed, they affect both human health and the environment. Approach: This study evaluated the mutagenic potentials of effluents from six pharmaceutical companies in the Lagos province of Nigeria using modified Ames … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 7,509 accessesView PDF Cite

Research ArticleOpen accessIn the abstractIdentification of Novel Chromosomal Abnormalities, inv(5)(p13q13) and t(7;18)(q32;q21), Associated with AutismZheng Chen, Xiao-bing Zou, Ya-nan Zhang et al.Autism is a neurodevelopmental disorder defined by impairments in social interaction, communication, as well as restricted and stereotyped behaviors. While the etiology of autism remains largely unknown, the existence of genetic components has been clearly demonstrated in autistic pathogenesis. The incidence of autism is 50-100 fold greater in the population with autistic family history than the general population. Chromosomal abnormalities … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 3 · 30 Sep 2007 · 6,773 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordGenotoxicity through Exposure to Particulate Matter (PM10) at two Sites in the Valle de Aburrá, ColombiaVerónica Estrada-Vélez, Lucelly López-López, Lina María Martínez-Sánchez et al.To establish differences in the genotoxic effect of particulate matter (PM10) in exposed individuals at two sites in the Valle de Aburrá (VA). This was a descriptive cross-sectional study of 2 groups of individuals exposed to 67.7 and 45 µg/m3 of PM10 for a minimum of 8 hours/day. The frequency of Chromosomal Abnormalities (CAs) and the mitotic index were evaluated … …OnLine Journal of Biological Sciences, Vol. 19, Issue 1 · 19 Mar 2019 · 8,368 accessesView PDF Cite