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10 results for “cerebral cortex”
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Research ArticleOpen accessIn the keywordsEffect of New Compound with Antioxidant Potential in the Energy Metabolism of Adults Rats after Pneumococcal MeningitisT. Barichello, Geovana Dagostim Savi, A. P. Panatto et al.Problem statement: In bacterial meningitis, the Streptococcus pneumoniae can modify the cerebro-spinal fluid (CSF) homeostasis and initiation of the host inflammatory response with presence cytokine and leukocyte migration into the subarachnoidal space. Despite the availability of highly effective antibiotics, the disease is often fatal or causes long-term neurological problems in affected patients. Approach: The aim of this study was to … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 2 · 15 Jun 2012 · 7,788 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA Microscopic Study of Language-Related Cortex in AutismEdith López-Hurtado, Jorge J. PrietoImpaired language function is a principle criterion for the diagnosis of autism. The present study of brain from age-matched autistic and control subjects compared brain regions associated with the production and processing of speech. Wernicke's area (Brodmann 22, speech recognition), Broca's area (Brodmann 44, speech production) andthe gyrus angularis (Brodmann 39, reading) from autistic subjects (7-44 years of age) and … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 8,544 accessesView PDFCite
Research ArticleOpen accessIn the abstractWhale Optimized Deep Generative Adversarial Network Based Alzheimer's Stages Detection Using 3D MRI Brain NeuroimagingR. Sampath, M. BaskarAlzheimer's Disease (AD), a common, chronic neurodegenerative condition, is characterized by the loss of neurons and synapses in the cerebral cortex and specific subcortical regions. According to claims from a recent study, AD has a 20% misdiagnosis rate. Therefore, it is essential to create a useful tool to recognize the stages of AD with a lower prediction error rate to … …Journal of Computer Science, Vol. 19, Issue 8 · 4 Aug 2023 · 5,544 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Curcumin and Physical Training on the Brain and Motor Performance of Rats with Cerebral IschemiaKarine Sthéfany Serpa Amaral Dias, Jonas Augusto Ramos, Bruno Mattiello Gomes et al.Brain ischemia is the second most deadly disease in the world and it has already been proven that mild and moderate physical exercises minimize the deleterious effects of this disease on the brain. Curcumin has also been considered a neuroprotective substance. Therefore, the goal of this study was to evaluate the effects of high-resistance training and curcumin on the brain … …Neuroscience International, Vol. 10, Issue 1 · 25 Apr 2019 · 7,765 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Exercise Prior or After Ischemia on the Density of Neurons and Astrocytes in the Brain of RatsLaila Cristina Moreira Damázio, Raphael Teixeira Rocha Melo, Maira de Castro Lima et al.The aim of this study was to analyse the density of astrocytes and neurons in the motor areas of the cortex, striatum and hippocampus of rats that performed exercise before or after cerebral ischemia. A total of 36 Wistar rats were separated into two groups: One that was subjected to Middle Cerebral Artery Occlusion (MCAO) and the other that underwent … …Neuroscience International, Vol. 5, Issue 2 · 14 Jan 2015 · 7,345 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuronal Necrosis Due to a Lethal Epileptic Syndrome Affecting FVB Strain β-Actin Luciferase Transgenic MiceAhmed Shoieb, Rachel Allavena, Abdelazim IbrahimThe FVB is the most often inbred mouse strain used in transgenic research. This strain is recognised to be affected with a disease known as FVB Lethal Epileptic Syndrome (FLES). A case series of FVB mouse lethal epileptic syndrome in a cohort of commercially procured β actin luciferase transgenic FVB mice was diagnosed based on the clinical signs, post-mortem and … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 10 Dec 2014 · 7,482 accessesView PDFCite
Research ArticleOpen accessIn the abstractCoscinium Fenestratum Protects Against Ethanol-Induced Neurodegeneration in Adult Rat BrainWathita Phachonpai, Jintanaporn Wattanathorn, Panakaporn Wannanon et al.Alcoholism is a serious problem throughout the world. Despite intensive efforts to develop novel therapeutics for strategy efficacy against neuronal loss leading to memory impairment in alcoholism is still limited. In view of the pitfalls of psychological dependence and adverse behavioral effects of synthetic drugs, the development of low toxicity and high efficiency medicines derived from natural herbal antioxidants exhibits … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 3 · 16 Aug 2012 · 8,602 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrenatal Exposure to Chronic Ethanol on N Methyl D Aspartate Receptor DistributionM. Taherianfard, B. Geramizadeh, E. Evazi, M. SharifiProblem statement: Effect of chronic exposure to ethanol on NR1 subunit of the NMDA receptor distribution in chick embryo brain chronic ethanol intake leads to the development of dependence on and tolerance to ethanol in both human and animals. The glutamate system plays a major role in mediating ethanol effects on brain and behavior. The aim of the present study … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 4 · 21 Feb 2012 · 7,301 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuroprotective Effect against Cerebral Ischemia of Passiflora foetidaJintanaporn Wattanathorn, Natcha Sattroopinat, Terdthai Tong-Un et al.Problem statement: Although cerebral ischemia induced by stroke has been regarded as the important problem worldwide, the therapeutic efficacy is still inadequate. Since the free radicals are implicated in the pathophysiology of cerebral ischemia, the prophylactic protection against stroke with neuroprotective agent possessing antioxidant effect has gained much attention. Therefore, this study was designed to determine whether the alcoholic extract … …American Journal of Applied Sciences, Vol. 9, Issue 4 · 16 Feb 2012 · 8,242 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Biomechanical Composite Model to Determine Effective Elastic Moduli of the CNS Gray MatterMehdi Khoshgoftar, Siamak Najarian, Farhad Farmanzad et al.Brain tissue is a heterogeneous material with complicated microstructural features. Models based on microstructure can lead to more accurate and physically realistic predictions of mechanical characteristics of brain tissue. A two-step Mori-Tanaka/Voigt homogenization procedure is implemented into a 3D microstructurally-based multi-phase composite model, composed of randomly-oriented elastic axons, dendrites and neuronal cell bodies surrounded by an elastic matrix. The effects … …American Journal of Applied Sciences, Vol. 4, Issue 11 · 30 Nov 2007 · 7,775 accessesView PDFCite