4 results for “cell neoplasm”

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Research ArticleOpen accessPhrase in the titleZeta Chain-Associated Protein-70 Expression is a Prognostic Tool in Mature and Precursor B-Cell NeoplasmNadia E. ElMenshawy, Sherin A. Abd ElAziz, Heba A. El Deghadi et al.Problem statement: The Zeta Chain-Associated Protein (ZAP) is a 70-kDa molecule associated with the zeta chain of the CD3 receptor complex of the lymphocyte population. It plays an important role in signaling initiation, activation T-cell receptor, phosphorylation of multiple downstream targets. So that believed as T. lymphocyte specific .Several studies is gathering that the pattern of expression is not lineage … …Current Research in Medicine, Vol. 2, Issue 1 · 9 Jul 2011 · 7,299 accessesView PDF Cite

Research ArticleOpen accessIn the abstractCell-Based Therapies in the Prevention of Solid Organ Transplant RejectionAdrian E. Morelli, Sherrie J. DivitoProblem statement: Organ transplantation is a life-saving and increasingly common procedure, as it often serves as the only treatment available for end-stage organ disease. Although the constant development of new and more effective immunosuppressive drugs has revolutionized the prevention and treatment of acute graft rejection, these drugs have significant toxicity, greatly increase patient susceptibility to neoplasms and infection and exert … …American Journal of Immunology, Vol. 8, Issue 2 · 26 Jul 2012 · 7,416 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordSelective Susceptibility of Human Bladder Transitional Cell Carcinoma T24 Cells towards NBD PeptideSankari Durairajan, Charles Emmanuel Jebaraj Walter, Kalaiselvi Periyandavan et al.Bladder cancer is a recurrent disease that often develops chemoresistance and is on the rise in developing countries. After diagnosis surgery followed by immunotherapy and/or chemo- radiation therapy are the available treatments. These treatments do not provide protection against disease progression or recurrence thus highlighting the need to identify and develop drugs that are capable of inhibiting bladder cancer. T24 … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 20 Apr 2020 · 7,787 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordThe Tumor/Immune Interface: Clinical Evidence of Cancer Immunosurveillance, Immunoediting and ImmunosubversionMatthew S. Block, Svetomir N. MarkovicProblem statement: The interactions of a malignant tumor with the patient’s immune system are dynamic, multiple and bi-directional. Approach: This article reviews the clinical evidence of the interaction of cancer with immunity with emphasis on recent developments highlighting some of the mechanisms of tumor-mediated regulation of immunity. Results: Most of the time, the immune response to a malignancy acts to … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Mar 2009 · 10,095 accessesView PDF Cite