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6 results for “bioautography”
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Research ArticleOpen accessEvery word in the titleBioautography Guided Identification of Anticandidal Compounds from A. terreus st. 1B. K. Nagaraja, R. Sripathy, C. N. Ramchand, M. SundararamanProblem statement: Saprophytic and soil inhabiting microorganisms are prolific producers of secondary metabolites with wide range of structural and functional diversity. The objective of the current study was to screen and evaluate the anti-candidal properties of soil inhabiting fungi. Approach: Preliminary dual culture assay and bioautography was used to screen the fungi with potential anti-fungal activity and direct detection of … …American Journal of Infectious Diseases, Vol. 7, Issue 4 · 1 Dec 2011 · 7,629 accessesView PDFCite
Research ArticleOpen accessIn the keywordsZerumbone: A Natural Compound with Anti-Cholinesterase ActivityAhmad Bustamam, Siddig Ibrahim, Adel S. Al-Zubairi et al.Herbal dugs could be a new source for inhibitors of acetyl cholinesterase (anti-AChE), the key enzyme in the breakdown of acetylcholine and a new talented approach for the cure of elderly neurologically associated disorders such as Alzheimer’s disease (AD). Zerumbone (ZER) is sesquiterpene from the edible plant, Zingiber zerumbet which is known to possess tremendous biological activities. In this study, … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 3 · 30 Sep 2008 · 9,638 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Crude Aqueous Extract of Piper betle L. and its Antibacterial Effect Towards Streptococcus mutansT. Nalina, Z.H.A. RahimIn this study, the antimicrobial influence of crude aqueous extract of Piper betle L. on Streptococcus mutans (S. mutans) was investigated. The focus of the antimicrobial effects includes the ultrastructure and acid producing properties of S. mutans. Transmission electron microscopy (TEM) was used to determine the effect of the extract on the ultrastructure of S. mutans. Analysis of the effect … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 1 · 31 Mar 2007 · 13,459 accessesView PDFCite
Research ArticleOpen accessIn the abstractBio-Guided Study on Melastoma malabathricum Linn Leaves and Elucidation of its Biological ActivitiesMourouge Saadi Alwash, Nazlina Ibrahim, Wan Yaacob AhmadThe present study aimed to isolate and identify constituents with antibacterial activity from the Methanol extract of Melastoma malabathricum leaves (MMML) through bioassay guided fractionation. Furthermore, the study scoped to evaluate the cytotoxic effects of M. malabathricum leaves fractions for possible protective effect of antoxidative constituents present in the fractions. The MMML extract was fractionated by Vacuum Liquid Chromatography (VLC) … …American Journal of Applied Sciences, Vol. 10, Issue 8 · 24 Jul 2013 · 9,513 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification and Mode of Action of Antibacterial Components from Melastoma malabathricum Linn LeavesMourouge Saadi Alwash, Nazlina Ibrahim, Wan Yaacob AhmadThe present study aimed to assess the antibacterial activity of the methanol extract of Melastoma Malabathricum Leaves (MMML), active fraction of M. Malabathricum Leaves (ML5) and isolated kaempferol-3-O-(2",6"-di-O-p-trans-coumaroyl)-β-glucopyranoside (Kf) and to describe the preliminary mode of action against Gram-positive and Gram-negative bacteria. The MMML extract was fractionated by Vacuum Liquid Chromatography (VLC) to afford M. malabathricum Leaves fractions (ML1-ML6) of … …American Journal of Infectious Diseases, Vol. 9, Issue 2 · 18 Jun 2013 · 12,621 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioassay Guided Isolation of Antibacterial Compounds from Andrographis paniculataAbubakar Sule, Qamar Uddin Ahmed, Othman Abd. Samah et al.Problem statement: Chronic disease-causing bacteria of medical importance have developed resistance to antibiotics, hence, necessitating distinct and constant need for safe and efficient therapeutic agents. Plants are considered potent candidate for this aim. A way out of reducing antibiotic resistance and adverse effects on host is the employment of antibiotic resistance inhibitors of plant origin. Approach: About 5 kg pulverized … …American Journal of Applied Sciences, Vol. 8, Issue 6 · 13 Jun 2011 · 10,025 accessesView PDFCite