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10 articles for “arginine”
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Research ArticleOpen accessEvery word in the titleREMEDIAL EFFECTS OF VITAMIN E AND L-ARGININE ON PERIPHERAL NEUROPATHY IN STREPTOZOTOCIN-INDUCED DIABETIC RATSIsmaeel Bin-Jaliah, Samah El-Attar, Eman F. Khaleel et al.It was shown that hyperglycemia in diabetic patients is the main factor of diabetic peripheral neuropathies. Various pathways related to oxidative stress, vascular defect and defective endothelium dependent relaxation have been implicated in the development of diabetic peripheral neuropathy. A substantial number of studies have shown that antioxidant treatment are promising therapeutics that can prevent or correct reduced motor nerve … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 23 Dec 2013 · 8,041 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDihydrobiopterin (BH2): Key Determinant in Influencing Arginine Mediated Endothelial Tolerance and DysfunctionSrinidi Mohan, Harsh Patel, Jorge Bolinaga et al.The redox-sensitive tetrahydrobiopterin (BH4) is an essential cofactor that is required by endothelial Nitric Oxide Synthase (eNOS) for L-arginine (ARG) mediated Nitric Oxide (NO) generation. Oxidation of BH4 causes cofactor insufficiency and uncoupling of eNOS, resulting in product switching from NO to O2⋅– production. Here we tested the hypothesis that eNOS uncoupling is not simply a consequence of BH4 insufficiency, … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 8,348 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCardiac Depression Produced by L-Arginine and Phosphodiestrase Inhibitor on Isolated Mammalian Rabbit Heart: Function of Cyclic Guanosine Monophosphate (cGMP)Hussein F. Sakr, Fahaid Al-Hashem, Mahmoud Al-Khateeb et al.Problem statement: Cyclic guanosine 3',5'-monophosphate cGMP is one the important second messengers that determines the cardiomyocyte activity and its role in healthy and diseased cardiac muscle is still controversial. We are reporting the effect of adding L-arginine, the NO donor that stimulates cGMP production and Sildenafil citrate (phosphodiestrase inhibitor) that inhibits cGMP hydrolyis on isolated rabbit’s heart to answer: Is … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 8,182 accessesView PDFCite
Literature ReviewOpen accessIn the abstractUnraveling NETosis: From Immune Mechanisms to Therapeutic InnovationsAnastasia V. Poznyak, Alexey V. Churov, Gulalek Amanmyradovna Babayeva et al.Neutrophil Extracellular Traps (NETs) are integral to immune responses, serving both protective and pathological roles in inflammatory diseases. Despite increasing recognition of NETs, significant gaps remain in understanding the nuanced mechanisms of NETosis and its implications for health and disease. This review systematically explores NETosis—the formation of NETs—by elucidating the molecular signaling pathways and cellular mechanisms involved. We highlight the … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 21 Feb 2026 · 1,678 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Assessment of Meat Quality Characteristics of Cattle Depending on Breed, Age and Growing Conditions in the Republic of KazakhstanGulzat Oraz, Asan Ospanov, Urishbay Chomanov et al.The results of meat productivity of young cattle of beef breeds (Auliekol, Kazakh Whitehead, Galloway, Hereford) depending on the breed, sex, and age (young bulls, steers-calves, heifers, first-calf cows, adult cattle-cows, bulls, calves) grown in the Western Region of the Republic of Kazakhstan during winter, turning winter (pre-spring), early spring and spring periods are given. The animals were divided into … …OnLine Journal of Biological Sciences, Vol. 22, Issue 2 · 19 May 2022 · 6,940 accessesView PDFCite
Research ArticleOpen accessIn the abstractEcophysiological Studies on Saudi Wild Safflower (Carthamus Oxyacantha Bieb) Seed EcotypesSulaiman Mohammed Al Fadal, Mohammed Abd-Elwahab Al-FredanCarthamus oxyacantha is a widespread wild safflower species in Middle Eastern countries and northwestern India, including Kazakhstan, Turkmenistan and Uzbekistan and the Kingdom of Saudi Arabia. This study was conducted to evaluate and compare four C. oxyacantha ecotypes collected from different regions in the Kingdom of Saudi Arabia, Al-Hassa, Al-Kharaj, Najran and Al- Jouf. Analysis of variance showed significant effects … …American Journal of Environmental Sciences, Vol. 11, Issue 3 · 8 Aug 2015 · 7,562 accessesView PDFCite
EditorialOpen accessIn the abstractNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,737 accessesView PDFCite
Research ArticleOpen accessIn the abstractInhibition of Panton-Valentine Leukocidin Toxin Induced Neutrophil Cell Lysis by Vancoplus in Methicillin-Resistant Staphylococcus Aureus InfectionsManu Chaudhary, Santosh Kumar Patnaik, Anurag PayasiPantone Valentine Leukocidin (PVL) is a cytotoxin associated with virulence of Methicillin-Resistant Staphylococcus aureus (MRSA). This study was undertaken to analyze the prevalence of PVL among MRSA strains and to study the effect of adjuvants (L-lysine, L-arginine, Ethylenediamine Tetraacetic Acid (EDTA) as well as drugs on PVL induced neutrophil cell lysis. Further, in vitro activity of Vancoplus, vancomycin, linezolid, teicoplanin … …American Journal of Infectious Diseases, Vol. 10, Issue 4 · 20 Dec 2014 · 7,106 accessesView PDFCite
Research ArticleOpen accessIn the abstractEFFECTS OF SUPPLEMENTAL LYSINE ON PERFORMANCE, ANTIBODY TITER AND RECTAL TEMPERATURE IN RESPONSE TO A MODIFIED-LIVE VIRAL VACCINE IN NEONATAL CALVESKate Sharon, Glenn Duff, Jeff Dailey et al.Infectious Bovine Rhinotracheitis (IBR), caused by bovine herpesvirus-1, contributes significantly to economic losses in the dairy and beef cattle industry. Lysine has been shown reduce virulence of herpesviruses in felids and humans. Our objective was to evaluate the effects of supplemental lysine on serum IBR antibody titer and rectal temperature in response to a modified-live Intranasal (IN) or Intramuscular (IM) … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 2 · 2 Jun 2014 · 7,606 accessesView PDFCite
Research ArticleOpen accessIn the abstractNutrient and the Mind-Body Axis, in Relation to Omega-3 Fatty Acids and Amino AcidsToru Takahashi, Eri Toda, Ram B. Singh et al.Noncommunicable Diseases (NCDs); obesity, type 2 diabetes mellitus, Cardiovascular Diseases (CVDs) and cancer have become major health problems in both developing and developed countries. Physical inactivity and increased intake of energy rich proinflammatory foods in association with genetic predisposition are common primary risk factors for these problems. Mind-body interactions and mechanisms in relation to hypothalamus neurotransmitters and vagus nerve have … …Current Research in Medicine, Vol. 3, Issue 1 · 17 Feb 2012 · 7,322 accessesView PDFCite